Stress-Induced Changes in the Lipid Microenvironment of β-(1,3)-D-Glucan Synthase Cause Clinically Important Echinocandin Resistance in Aspergillus fumigatus

Candida albicans gains azole resistance by altering sphingolipid composition

(2018) Jiaxin Gao et al.   Nature Communications

The paradoxical effect of echinocandins in Aspergillus fumigatus relies on recovery of the β-1,3-glucan synthase Fks1.

(2016) Veronika Loiko et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical implications of globally emerging azole resistance inAspergillus fumigatus

(2016) Jacques F. Meis et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Amphotericin B Resistance in Aspergillus terreus Is Overpowered by Coapplication of Pro-oxidants

(2015) Michael Blatzer et al.   ANTIOXIDANTS & REDOX SIGNALING

Echinocandin Resistance in Candida

(2015) David S. Perlin   CLINICAL INFECTIOUS DISEASES

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Ballgown bridges the gap between transcriptome assembly and expression analysis

(2015) Alyssa C Frazee et al.   NATURE BIOTECHNOLOGY

Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus

(2015) Robert Altwasser et al.   PLoS One

TOR Complex 2-Ypk1 Signaling Maintains Sphingolipid Homeostasis by Sensing and Regulating ROS Accumulation

(2014) Brad J. Niles et al.   Cell Reports

Elevated Chitin Content Reduces the Susceptibility of Candida Species to Caspofungin

(2012) Louise A. Walker et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The changing epidemiology of healthcare-associated candidemia over three decades

(2012) Daniel Diekema et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Topological and Mutational Analysis of Saccharomyces cerevisiae Fks1

(2012) Michael E. Johnson et al.   EUKARYOTIC CELL

CRS-MIS inCandida glabrata: sphingolipids modulate echinocandin-Fks interaction

(2012) Kelley R. Healey et al.   MOLECULAR MICROBIOLOGY

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Candida glabrataMutants Demonstrating Paradoxical Reduced Caspofungin Susceptibility but Increased Micafungin Susceptibility

(2011) Kelley R. Healey et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mitochondria and Fungal Pathogenesis: Drug Tolerance, Virulence, and Potential for Antifungal Therapy

(2011) Miguel Shingu-Vazquez et al.   EUKARYOTIC CELL

Current perspectives on echinocandin class drugs

(2011) David S Perlin   Future Microbiology

Transcriptional Regulation of Chitin Synthases by Calcineurin Controls Paradoxical Growth of Aspergillus fumigatus in Response to Caspofungin

(2010) J. R. Fortwendel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2

(2010) Michael J. Dagley et al.   MOLECULAR MICROBIOLOGY

Effect of Candida glabrata FKS1 and FKS2 Mutations on Echinocandin Sensitivity and Kinetics of 1,3- -D-Glucan Synthase: Implication for the Existing Susceptibility Breakpoint

(2009) G. Garcia-Effron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria

(2009) Yasushi Tamura et al.   JOURNAL OF CELL BIOLOGY

The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria

(2009) Christof Osman et al.   JOURNAL OF CELL BIOLOGY

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

Breakthrough Aspergillus fumigatus and Candida albicans Double Infection during Caspofungin Treatment: Laboratory Characteristics and Implication for Susceptibility Testing

(2008) M. C. Arendrup et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Correlating Echinocandin MIC and Kinetic Inhibition of fks1 Mutant Glucan Synthases for Candida albicans: Implications for Interpretive Breakpoints

(2008) G. Garcia-Effron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Gain-of-Function Mutation in the Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Increased Fluconazole Resistance in a ClinicalCandida albicansIsolate

(2008) Nico Dunkel et al.   EUKARYOTIC CELL