期刊
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
卷 602, 期 -, 页码 69-79出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.abb.2016.02.029
关键词
Small angle X-ray scattering; Complex structural analysis; Intrinsically disordered proteins; Advanced sample environments; Hybrid biostructural analysis
资金
- Novo Nordisk Fonden [NNF13OC0006661] Funding Source: researchfish
Solution small angle X-ray scattering from biological macromolecules (BioSAXS) plays an increasingly important role in biostructural research. The analysis of complex protein mixtures, dynamic equilibriums, intrinsic disorder and evolving structural processes is facilitated by SAXS data, either in standalone applications, or with SAXS taking a prominent role in hybrid biostructural analysis. This is not the least due to the significant advances in both hardware and software that have taken place in particular at the large-scale facilities. Here, recent developments and the future potential of BioSAXS are reviewed, exemplified by numerous examples of elegant applications to challenging systems. (C) 2016 The Author. Published by Elsevier Inc.
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