期刊
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
卷 589, 期 -, 页码 4-9出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.abb.2015.08.024
关键词
Metabonomics research; Sample preparation; Data pre-treatment
资金
- National Natural Science Foundation of China [21375144, 21175149, 91439102]
- Ministry of Science and Technology of China [2012CB934004]
Metabonomics is a powerful approach for biomarker discovery and an effective tool for pinpointing endpoint metabolic effects of external stimuli, such as pathogens and disease development. Due to its wide applications, metabonomics is required to deal with various biological samples of different properties. Hence sample preparation and corresponding data pre-treatment become important factors in ensuring validity of an investigation. In this review, we summarize some recent developments in metabonomics sample preparation and data-pretreatment procedures. (C) 2015 Elsevier Inc. All rights reserved.
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