期刊
SEMINARS IN PERINATOLOGY
卷 44, 期 1, 页码 -出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.semperi.2019.07.007
关键词
Congenital diaphragmatic hernia; Cardiac function; Pulmonary hypertension; Echocardiography; Ventricular function
There is increasing evidence that cardiac dysfunction is a key contributor to CDH pathophysiology. Dysfunction in both right and left ventricles is common in the early neonatal period, contributes to clinical disease severity, and is associated with adverse outcomes including death and ECMO use. Early and routine assessment of ventricular function and pulmonary artery pressure may guide individualized clinical decision-making, including use of pulmonary vasodilators, cardiotropes, ECMO, and timing of surgical repair. Minimizing cardiac dysfunction, whether by prenatal, postnatal or perinatal treatment strategies, may lead to improved outcome in CDH. (C) 2019 Elsevier Inc. All rights reserved.
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