Novel liquid-liquid extraction and self-emulsion methods for simplified isolation of extra-virgin olive oil phenolics with emphasis on (-)-oleocanthal and its oral anti-breast cancer activity

The Biological Activities of Oleocanthal from a Molecular Perspective

(2018) Kok-Lun Pang et al.   Nutrients

The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment

(2017) Nehad M. Ayoub et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Extraction of phenolic compounds from virgin olive oil by deep eutectic solvents (DESs)

(2016) Aránzazu García et al.   FOOD CHEMISTRY

The biological activities of natural lignans from olives and virgin olive oils: A review

(2016) Alicia López-Biedma et al.   Journal of Functional Foods

Oleocanthal Enhances Amyloid-β Clearance from the Brains of TgSwDI Mice and in Vitro across a Human Blood-Brain Barrier Model

(2015) Hisham Qosa et al.   ACS Chemical Neuroscience

Mediterranean diet and other lifestyle factors in relation to 20-year all-cause mortality: a cohort study in an Italian population

(2015) Federica Prinelli et al.   BRITISH JOURNAL OF NUTRITION

New drugs from ancient natural foods. Oleocanthal, the natural occurring spicy compound of olive oil: a brief history

(2015) Morena Scotece et al.   DRUG DISCOVERY TODAY

Preparative isolation of oleocanthal, tyrosol, and hydroxytyrosol from olive oil by HPCCC

(2015) Hamid-Reza Adhami et al.   FOOD CHEMISTRY

Quantitative analysis of pungent and anti-inflammatory phenolic compounds in olive oil by capillary electrophoresis

(2015) Isabella Vulcano et al.   FOOD CHEMISTRY

Olive Oil-derived Oleocanthal as Potent Inhibitor of Mammalian Target of Rapamycin: Biological Evaluation and Molecular Modeling Studies

(2015) Mohammad A. Khanfar et al.   PHYTOTHERAPY RESEARCH

One-Step Semisynthesis of Oleacein and the Determination as a 5-Lipoxygenase Inhibitor

(2014) Konstantina Vougogiannopoulou et al.   JOURNAL OF NATURAL PRODUCTS

Olive Phenolics as c-Met Inhibitors: (-)-Oleocanthal Attenuates Cell Proliferation, Invasiveness, and Tumor Growth in Breast Cancer Models

(2014) Mohamed R. Akl et al.   PLoS One

Olive secoiridoids and semisynthetic bioisostere analogues for the control of metastatic breast cancer

(2013) Belnaser A. Busnena et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Oleocanthal Inhibits Proliferation and MIP-1α Expression in Human Multiple Myeloma Cells

(2013) M. Scotece et al.   CURRENT MEDICINAL CHEMISTRY

Pinoresinol Inhibits Proliferation and Induces Differentiation on Human HL60 Leukemia Cells

(2013) Maria Vittoria Sepporta et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Oleuropein and oleacein may restore biological functions of endothelial progenitor cells impaired by angiotensin II via activation of Nrf2/heme oxygenase-1 pathway

(2013) Andrzej Parzonko et al.   PHYTOMEDICINE

Direct Measurement of Oleocanthal and Oleacein Levels in Olive Oil by Quantitative 1H NMR. Establishment of a New Index for the Characterization of Extra Virgin Olive Oils

(2012) Evangelia Karkoula et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Modulation of Tau Protein Fibrillization by Oleocanthal

(2012) Maria Chiara Monti et al.   JOURNAL OF NATURAL PRODUCTS

p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis

(2011) P. Khanal et al.   CARCINOGENESIS

A comparison of antioxidant activities of oleuropein and its dialdehydic derivative from olive oil, oleacein

(2011) Monika Czerwińska et al.   FOOD CHEMISTRY

(−)-Oleocanthal as a c-Met Inhibitor for the Control of Metastatic Breast and Prostate Cancers

(2011) Ahmed Elnagar et al.   PLANTA MEDICA

Cytotoxic and EGFR tyrosine kinase inhibitory activities of aglycone derivatives obtained by enzymatic hydrolysis of oleoside-type secoiridoid glucosides, oleuropein and ligustroside

(2010) Masafumi Kikuchi et al.   Journal of Natural Medicines

Alzheimer's-associated Aβ oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal

(2009) Jason Pitt et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

tabAnti-HER2 (erbB-2) oncogene effects of phenolic compounds directly isolated from commercial Extra-Virgin Olive Oil (EVOO)

(2008) Javier A Menendez et al.   BMC CANCER