Article
Immunology
Alessandra Beni, Sara Mazzilli, Elisabetta Bellino, Giorgio Costagliola, Elena Ferretti, Pier Luigi Lopalco, Lara Tavoschi, Diego Giampietro Peroni
Summary: Children with chronic conditions may face challenges in receiving additional vaccinations, such as inadequate knowledge among healthcare providers and low coverage of recommended vaccines. The review of national immunization plans presents an opportunity to address these issues and improve vaccination rates for this vulnerable population.
Article
Public, Environmental & Occupational Health
Michele Sorrentino, Michelangelo Mercogliano, Federica Esposito, Agostina Maria Lamberti, Gaetano Buonocore, Carla Riganti, Maria Triassi, Raffaele Palladino
Summary: This study assesses the HPV vaccination uptake and its correlates among medical students and identifies barriers, knowledge, and attitudes towards HPV vaccination. The findings suggest that an active and up-to-date call strategy and extending the free-of-charge offer are essential measures to improve vaccination uptake.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Infectious Diseases
Lynn Williams, Karen Deakin, Allyson Gallant, Susan Rasmussen, David Young, Nicola Cogan
Summary: The decision to accept influenza vaccination in patients with chronic respiratory conditions is influenced by multiple sociodemographic and psychological factors. Future interventions should provide clear and transparent information about side effects and be tailored to patients with chronic respiratory conditions. Interactions between patients and their healthcare providers play a crucial role in helping patients address concerns and feel confident in vaccination.
INFLUENZA AND OTHER RESPIRATORY VIRUSES
(2021)
Article
Biotechnology & Applied Microbiology
Sawsan Mubarak, Hadeel Alghawrie, Bayan Qaddumi
Summary: This study examines the knowledge, attitudes, concerns, behaviors, and barriers related to seasonal influenza vaccination among healthcare workers in the oncology setting during the COVID-19 pandemic. The study found that the coverage rates for seasonal influenza vaccination showed a significant increase from 2019 (65%) to 2020 (81%), despite the challenges posed by the pandemic. Furthermore, the participants expressed a strong willingness to receive the vaccine in the autumn of 2021 and exhibited good knowledge about it.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2023)
Article
Immunology
Yi Xu, Min Ting Alicia See, Fazila Aloweni, Chun Hui Fion Koh, Cheng Gaik Irene Tan, Xiao Hui Xin, Wee Hoe Gan, Lian Leng Low, Su Fee Lim
Summary: The study aimed to explore the factors influencing vaccine uptake and the impact of COVID-19 on vaccine uptake among community-dwelling older adults in Singapore. Living arrangement was found to be a significant contributing factor, with those living alone more likely to be vaccinated. Key enablers for vaccine uptake included avoidance of infection and transmission, as well as healthcare professionals' advice, while barriers included concerns about side effects, vaccine effectiveness, and lack of information. Greater public health efforts and information provision by healthcare professionals are needed to encourage vaccine uptake, especially during COVID-19.
Article
Public, Environmental & Occupational Health
Md Zakiul Hassan, Tahmina Shirin, Mahbubur Rahman, A. S. M. Alamgir, Nusrat Jahan, Md Abdullah Al Jubayer Biswas, Sazzad Hossain Khan, Md Ahmed Khairul Basher, Md Ariful Islam, Kamal Hussain, Md Nazrul Islam, Md Arif Rabbany, Md Azizul Haque, Shishir Ranjan Chakraborty, Syeda Rukhshana Parvin, Mahmudur Rahman, Fahmida Chowdhury
Summary: The study aims to investigate the effects of interventions on influenza vaccine awareness and supply availability among healthcare workers in Bangladesh, as well as their knowledge, perceptions, barriers, and motivators for vaccine uptake. Using a cluster randomized controlled trial approach at four hospitals, the study seeks to inform the development of a context-specific strategy to enhance influenza vaccination rates among Bangladeshi healthcare workers.
Article
Public, Environmental & Occupational Health
Ines Cherif, Ghassen Kharroubi, Leila Bouabid, Adel Gharbi, Aicha Boukthir, Nissaf Ben Alaya, Afif Ben Salah, Jihene Bettaieb
Summary: The study found a low vaccination rate among Tunisian healthcare workers, highlighting the importance of tailored education programs targeting this population.
Article
Biotechnology & Applied Microbiology
Qinwen Luo, Lin Gan, Yu Xiong, Qin Li, Tao Chen, Xiaojun Tang
Summary: The study found that over half of healthcare workers in Chongqing had good knowledge and positive attitudes towards influenza and its vaccine, but only a small percentage had actually received the vaccine last year. Various strategies such as educational training and on-site vaccination are needed to improve overall vaccination coverage.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Infectious Diseases
Alexander Domnich, Donatella Panatto, Elena Pariani, Christian Napoli, Maria Chironna, Ilaria Manini, Caterina Rizzo, Andrea Orsi, Giancarlo Icardi
Summary: This study aimed to compare the relative vaccine effectiveness of MF59-adjuvanted trivalent vaccine and non-adjuvanted quadrivalent vaccine against severe laboratory-confirmed influenza. The results showed that the MF59-adjuvanted vaccine was more effective in preventing severe acute respiratory infection.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Immunology
Fionnuala Cox, Catherine King, Anne Sloan, David J. Edgar, Niall Conlon
Summary: The majority of patients receiving IgRT understood and received influenza vaccination. However, many patients were not aware that vaccination was recommended for co-habitants, with only 24% of households having full vaccine coverage. Individuals who received advice on vaccinating household members had higher uptake rates.
JOURNAL OF CLINICAL IMMUNOLOGY
(2021)
Article
Immunology
Ibrahim M. Gosadi, Basem Zogel, Samar Alfaifi, Faisal Abusageah, Khalid M. Hakami, Taif Zogel, Tahani Altubayqi, Afnan Darsi, Ghaida Almuhaysin, Ali Ghalibi, Mohammed Alhazmi, Khulud Mahla
Summary: This study investigated the influenza vaccine uptake rates and barriers to its uptake among healthy subjects and patients with chronic diseases in the Jazan region of Saudi Arabia. The results showed that only a history of being diagnosed with a chronic disease was associated with ever receiving the influenza vaccine. The main barrier identified was fear of side effects, while healthcare workers had a limited role in motivating patients to have the vaccine.
Article
Public, Environmental & Occupational Health
I. Tsiligianni, I Bouloukaki, G. Papazisis, A. Paganas, E. Chatzimanolis, M. Kalatharas, I. Platakis, I. Tirodimos, T. Dardavesis, Z. Tsimtsiou
Summary: Insufficient adult vaccination coverage rates remain an international challenge. This study explored vaccination coverage and predictors of vaccine uptake in Greece and found that perception of disease risk, concerns about side-effects and efficacy, and mistrust in pharmaceutical companies were common factors associated with vaccine uptake. The strongest predictor of vaccination status was the doctor's recommendation, and being well-informed about each vaccine also influenced uptake.
Article
Public, Environmental & Occupational Health
Lisa P. Spees, Caitlin B. Biddell, Rebekah S. M. Angove, Kathleen D. Gallagher, Eric Anderson, Ashley Christenbury, Gabrielle Rocque, Stephanie B. Wheeler
Summary: Despite interventions to increase COVID-19 vaccination, differences in uptake persist, indicating that these interventions may not address barriers faced by certain populations. A survey of chronically ill patients demonstrated that informational and attitudinal barriers were more prevalent than logistical or structural access barriers, and attitudinal barriers were associated with vaccine uptake. Interventions should target attitudinal barriers among patients with chronic illness, particularly those without a usual source of care.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Pengchao Li, Khezar Hayat, Minghuan Jiang, Zhaojing Pu, Xuelin Yao, Yamin Zou, Krizzia Lambojon, Yifan Huang, Jinghua Hua, Hanri Xiao, Fulei Du, Li Shi, Panpan Zhai, Wenjing Ji, Zhitong Feng, Yilin Gong, Yu Fang
Summary: This study aims to increase influenza vaccination coverage in Chinese adults aged 60 and above using a video-led educational intervention conducted by medical students.
Article
Immunology
Kailey Hughes, Donald B. Middleton, Mary Patricia Nowalk, Goundappa K. Balasubramani, Emily T. Martin, Manjusha Gaglani, H. Keipp Talbot, Manish M. Patel, Jill M. Ferdinands, Richard K. Zimmerman, Fernanda P. Silveira
Summary: This study evaluated the vaccine effectiveness against influenza hospitalization among immunocompromised adults during the 2017-2018 influenza season. The results showed that while immunocompromised adults had a higher vaccination rate, their protection against influenza was lower, with a vaccine effectiveness of 33% in the overall adult population. Further research is needed to assess vaccine effectiveness among different immunocompromising conditions and explore ways to improve effectiveness for immunocompromised individuals.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Endocrinology & Metabolism
Paola Caruso, Maurizio Gicchino, Miriam Longo, Lorenzo Scappaticcio, Ferdinando Campitiello, Katherine Esposito
Summary: In this article, a case of a 39-year-old man with diabetes who developed severe soft tissue infection and osteomyelitis after undergoing major amputation for wet gangrene of both the foot and ankle is reported.
JOURNAL OF DIABETES INVESTIGATION
(2022)
Article
Endocrinology & Metabolism
Antonietta Maio, Maria Ida Maiorino, Miriam Longo, Lorenzo Scappaticcio, Vlenia Pernice, Paolo Cirillo, Paola Caruso, Vanda Amoresano Paglionico, Giuseppe Bellastella, Katherine Esposito
Summary: The study compared the levels of EPCs and sexual function changes during the menstrual cycle in women with T1DM and healthy women, finding lower EPCs levels and sexual function scores in diabetic women, particularly in the ovulatory phase.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Medicine, General & Internal
Marco Trabucco Aurilio, Maria Ida Maiorino, Francesco Saverio Mennini, Lorenzo Scappaticcio, Miriam Longo, Claudia Nardone, Luca Coppeta, Simone Gazzillo, Raffaele Migliorini, Giuseppe Bellastella, Dario Giugliano, Katherine Esposito
Summary: The study aimed to estimate the average number of claims for social security benefits from workers with diabetes-related disability in Italy. A nationwide retrospective cohort study using the database of the Italian Social Security Institute found a significant increase in both the number of applications and approvals for such benefits from 2009 to 2019, primarily represented by ordinary incapacity benefits for workers aged 51-60.
Article
Cardiac & Cardiovascular Systems
Magalie Ladouceur, Alexander Van De Bruaene, Robert Kauling, Werner Budts, Jolien Roos-Hesselink, Sandra Villagra Albert, Inmaculada Sanchez Perez, Berardo Sarubbi, Flavia Fusco, Pastora Gallego, Maria-Jose Rodriguez-Puras, Judith Bouchardy, Coralie Blanche, Tobias Rutz, Katja Prokselj, Fabien Labombarda, Laurence Iserin, Tom Wong, Michael A. Gatzoulis
Summary: The aim of this study was to investigate the occurrence of major adverse ventricular arrhythmias and related events in adults with a systemic right ventricle (sRV) and develop a stratification tool. The results showed that sudden cardiac death remains a devastating cause of death in this patient population. A prediction model based on clinical, electrocardiographic, and echocardiographic parameters was developed to estimate the risk of major adverse ventricular arrhythmias and identify high-risk patients who may benefit from primary prevention ICD implantation.
EUROPEAN HEART JOURNAL
(2022)
Review
Cardiac & Cardiovascular Systems
Raffaella Marzullo, Magalie Ladouceur, Gianpiero Gaio, Mario Giordano, Maria Giovanna Russo, Berardo Sarubbi
Summary: The increased trend of pregnancy among women with Congenital Heart Disease (CHD) has led to a growing demand for specialized care. Maternal CHD, especially in cases of Systemic Right Ventricle (SRV), may pose additional risks and challenges during pregnancy. Current literature lacks conclusive evidence on the feasibility and long-term effects of successful pregnancies in women with SRV.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Respiratory System
Berardo Sarubbi, Gabriella Farina, Diego Colonna, Anna Correra, Emanuele Romeo, Giovanni Domenico Ciriello, Guido Oppido, Maria Giovanna Russo
Summary: Placement of traditional transvenous ICD system in low-weight children is challenging due to vessel size and other anatomical constraints. Subcutaneous array leads combined with an abdominally placed ICD device are a potential alternative with minimal surgical trauma. This case series presents successful implantation of SFCD in low-weight children, showing good compliance and no complications or sustained ventricular arrhythmias requiring shocks.
MONALDI ARCHIVES FOR CHEST DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Flavia Fusco, Giancarlo Scognamiglio, Assunta Merola, Angela Iannuzzi, Michela Palma, Nicola Grimaldi, Berardo Sarubbi
Summary: Sacubitril/valsartan reduces hospitalization rate and mortality in heart failure patients and shows potential benefits in patients with a systemic right ventricle. This study demonstrates that the drug is well tolerated and improves systolic function, clinical status, and cardiac remodeling in this patient population.
CIRCULATION-HEART FAILURE
(2023)
Article
Endocrinology & Metabolism
Paola Caruso, Maria Ida Maiorino, Lorenzo Scappaticcio, Chiara Porcellini, Rita Matrone, Paolo Cirillo, Margherita Macera, Maurizio Gicchino, Maria Teresa Vietri, Giuseppe Bellastella, Nicola Coppola, Katherine Esposito
Summary: This study aimed to evaluate PTH levels in individuals with diabetic foot ulcers (DFU) and investigate the relationship between PTH levels and osteomyelitis (OM) in this population. The results showed that PTH levels were lower in DFU patients with OM compared to those without OM, and alkaline phosphatase levels were higher in the OM group. OM and alkaline phosphatase levels were independent predictors of PTH levels in this selected population.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Editorial Material
Endocrinology & Metabolism
Paola Caruso, Maria Ida Maiorino, Giuseppe Bellastella, Katherine Esposito, Dario Giugliano
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Review
Biochemistry & Molecular Biology
Michele Cerasuolo, Irene Di Meo, Maria Chiara Auriemma, Francesca Trojsi, Maria Ida Maiorino, Mario Cirillo, Fabrizio Esposito, Rita Polito, Anna Maria Colangelo, Giuseppe Paolisso, Michele Papa, Maria Rosaria Rizzo
Summary: Neurodegeneration is a complex process involving multiple mechanisms, with diseases like Parkinson's, multiple sclerosis, Alzheimer's, prion diseases, and ALS being examples. Iron overload has been identified as a potential cause of neurodegeneration, with dysregulated iron metabolism and increased oxidative stress being common in these diseases. Alzheimer's, in particular, shows increased iron content in vulnerable brain regions, leading to mitochondrial alterations and lack of antioxidant defenses. Iron metabolism and ferroptosis play a significant role in diabetes-induced cognitive decline, and iron chelators offer a promising therapeutic approach.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Cardiac & Cardiovascular Systems
Berardo Sarubbi, Giovanni Domenico Ciriello, Giovanni Papaccioli, Anna Correra, Emanuele Romeo, Nicola Grimaldi, Diego Colonna, Michela Palma
Summary: Subcutaneous implantable cardioverter defibrillators (S-ICD) are a safe alternative for complex congenital heart disease (CHD) patients with previously implanted pacemaker (PM) devices. They help avoid abandoned leads or life-threatening lead extraction. However, there are important issues regarding testing and programming that need to be addressed during implantation.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Article
Endocrinology & Metabolism
Dario Giugliano, Miriam Longo, Lorenzo Scappaticcio, Paola Caruso, Maurizio Gicchino, Michela Petrizzo, Giuseppe Bellastella, Maria Ida Maiorino, Katherine Esposito
Summary: The study aimed to assess the metabolic benefits of simplifying complex insulin regimens in patients with inadequately controlled type 2 diabetes. Results showed that simplification of treatment might be a durable option for at least half of patients.
Meeting Abstract
Public, Environmental & Occupational Health
G. D. Mauro, A. Mascolo, M. Longo, M. I. Maiorino, L. Scappaticcio, G. Bellastella, K. Esposito, A. Capuano
