Whole blood assay as a model for in vitro evaluation of inflammasome activation and subsequent caspase-mediated interleukin-1 beta release

Phenotype, function, and differentiation potential of human monocyte subsets

(2017) Lisa B. Boyette et al.   PLoS One

CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes

(2016) Wei Hseun Yeap et al.   Scientific Reports

Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability

(2016) Eva Hadadi et al.   Scientific Reports

Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes

(2015) Elena Viganò et al.   Nature Communications

Non-Classical monocytes display inflammatory features: Validation in Sepsis and Systemic Lupus Erythematous

(2015) Ratnadeep Mukherjee et al.   Scientific Reports

ATP-Induced IL-1β Specific Secretion: True Under Stringent Conditions

(2015) Monique Stoffels et al.   Frontiers in Immunology

Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation

(2015) Prajwal Gurung et al.   Scientific Reports

Mechanism of NLRP3 inflammasome activation

(2014) Fayyaz S. Sutterwala et al.   Annals of the New York Academy of Sciences

Localization and Functionality of the Inflammasome in Neutrophils

(2014) Martina Bakele et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Applying caspase-1 inhibitors for inflammasome assays in human whole blood

(2014) Katarzyna Lipinska et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function

(2014) M. G. Ghonime et al.   JOURNAL OF IMMUNOLOGY

FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes

(2014) P. Gurung et al.   JOURNAL OF IMMUNOLOGY

A Critical Role for Human Caspase-4 in Endotoxin Sensitivity

(2014) Y. Kajiwara et al.   JOURNAL OF IMMUNOLOGY

Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developments

(2013) Moritz Haneklaus et al.   CURRENT OPINION IN IMMUNOLOGY

Interleukin-1β triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells

(2013) Mirjam Schenk et al.   IMMUNOLOGY

Proapoptotic Chemotherapeutic Drugs Induce Noncanonical Processing and Release of IL-1  via Caspase-8 in Dendritic Cells

(2013) C. Antonopoulos et al.   JOURNAL OF IMMUNOLOGY

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

(2013) N. Kayagaki et al.   SCIENCE

Interleukin-18 and IL-18 Binding Protein

(2013) Charles A. Dinarello et al.   Frontiers in Immunology

Toward a Refined Definition of Monocyte Subsets

(2013) Loems Ziegler-Heitbrock et al.   Frontiers in Immunology

Impact of Human Granulocyte and Monocyte Isolation Procedures on Functional Studies

(2012) Lu Zhou et al.   Clinical and Vaccine Immunology

TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages

(2012) Yu Qiao et al.   FEBS LETTERS

Caspase-4 Is Required for Activation of Inflammasomes

(2012) G. Sollberger et al.   JOURNAL OF IMMUNOLOGY

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways

(2012) Peter J Murray et al.   NATURE IMMUNOLOGY

ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation

(2012) N Riteau et al.   Cell Death & Disease

Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

(2012) Manuela Rossol et al.   Nature Communications

Serum Amyloid A Activates the NLRP3 Inflammasome via P2X7 Receptor and a Cathepsin B-Sensitive Pathway

(2011) K. Niemi et al.   JOURNAL OF IMMUNOLOGY

A dual negative regulation model of Toll-like receptor 4 signaling for endotoxin preconditioning in human endotoxemia

(2011) Qian Yang et al.   MATHEMATICAL BIOSCIENCES

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

(2011) Stephen J Galli et al.   NATURE IMMUNOLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

A Protective Role for Inflammasome Activation Following Injury

(2011) Akinori Osuka et al.   SHOCK

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Temporal Interleukin-1β Secretion from Primary Human Peripheral Blood Monocytes by P2X7-independent and P2X7-dependent Mechanisms

(2010) Jon R. Ward et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative in vitro stimulation with lipopolysaccharide to study TNFα gene expression in fresh whole blood, fresh and frozen peripheral blood mononuclear cells

(2010) Jiwang Chen et al.   JOURNAL OF IMMUNOLOGICAL METHODS

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

(2009) Petronela Ancuta et al.   BMC GENOMICS

Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes

(2009) C. M. Larsen et al.   DIABETES CARE

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD

Whole-blood culture is a valid low-cost method to measure monocytic cytokines — A comparison of cytokine production in cultures of human whole-blood, mononuclear cells and monocytes

(2008) Camilla T. Damsgaard et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY