Article
Plant Sciences
Damien Hicks
Summary: This account provides comprehensive information on the biology of Corylus avellana L., including its distribution, habitat, interactions with other species, structure and physiology, herbivory and disease, history, and conservation. Hazelnuts in Britain and Ireland grow in a wide range of climates and ecological environments, and support a diverse community of fauna and fungi. They have a regenerative advantage and their pollen and fruit can cause allergic reactions in sensitive individuals. Corylus avellana is native to Europe and western Asia, and was one of the first plants to recolonize Europe after the last glacial period. It has effective gene flow and exhibits morphological variability.
JOURNAL OF ECOLOGY
(2022)
Review
Agronomy
Rosario Nicoletti, Beata Zimowska
Summary: The results of extensive research conducted worldwide in recent decades have shown that endophytic fungi play a crucial role in enhancing plant fitness by promoting growth and acting as defensive mutualists. These properties have potential applications in crop production, especially for tree species like hazelnuts grown extensively in semi-natural environments throughout temperate zones. This paper reviews the available data on the occurrence, ecological roles, and biotechnological applications of endophytic fungi associated with hazelnuts, aiming to provide a reference for future investigations and projects aimed at harnessing the potential of this component of the plant microbiome.
PLANT PROTECTION SCIENCE
(2023)
Review
Agronomy
Rosario Nicoletti, Beata Zimowska
Summary: Results of extensive research conducted worldwide have shown that endophytic fungi play a crucial role in enhancing plant fitness by promoting growth and acting as defensive mutualists. These properties have potential applications in crop production, particularly for tree species like hazelnut that are extensively cultivated in highland regions. This paper provides a review of the available data on the occurrence, ecological roles, and biotechnological applications of endophytic fungi associated with hazelnuts, aiming to support future investigations and projects focused on harnessing the potential of this component of the plant microbiome.
PLANT PROTECTION SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Cornel Balta, Hildegard Herman, Alina Ciceu, Bianca Mladin, Marcel Rosu, Alciona Sasu, Victor Eduard Peteu, Sorina Nicoleta Voicu, Mihaela Balas, Mihaela Gherghiceanu, Anca Dinischiotu, Neli Kinga Olah, Anca Hermenean
Summary: The study aimed to investigate the hepatoprotective effects of Corylus avellana bud extract in a liver fibrosis model on diabetic mice. The extract exhibited a flavonoids content of 6-7% with highlighted presence of hyperoside and chlorogenic acids. Liver fibrosis was induced with CCl4 injections in diabetic mice, resulting in increased oxidative stress, upregulation of TGF-β1/Smad 2/3 signaling pathway, activation of HSCs, and alteration of extracellular matrix. Treatment with the extract restored liver architecture, reduced oxidative stress and collagen deposits, and improved liver function. These findings suggest that Corylus avellana bud extract may have anti-fibrotic effects and could be beneficial in preventing and treating liver fibrosis.
Article
Agriculture, Multidisciplinary
Dilireba Shataer, Jun Li, Xiao-Mei Duan, Liu Liu, Xue-Lei Xin, Haji Akber Aisa
Summary: The study investigated the chemical composition of hazelnut kernels and their potential roles in COX-2 inhibition, antimicrobial effects, and antioxidant activities. Several new compounds were discovered and their absolute configurations were determined. Some of these compounds showed promising inhibitory effects on COX-2 expression and proliferation of Candida albicans, as well as strong antioxidant activity.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Horticulture
Adeyemi Oladapo Aremu, Nqobile P. Hlophe, Johannes Van Staden, Jeffrey F. Finnie
Summary: This review critically evaluates the ethnobotanical uses, nutritional value, phytochemical profiles, and biological activities of the Brachystelma genus. The potential of micropropagation in ensuring the sustainability of Brachystelma species is also assessed. The study finds that while there is anecdotal evidence of the food and medicinal uses of many Brachystelma species, empirical data on their nutritional and phytochemical profiles, as well as their biological activities, are lacking. Further research and optimization of propagation protocols are necessary to address this gap and ensure the sustainability of Brachystelma species.
Article
Chemistry, Multidisciplinary
Aleksandra Cvetanovic Kljakic, Alena Stupar, Milena Terzic, Jelena Bozunovic, Uros Gasic, Gokhan Zengin, Evren Yildiztugay
Summary: The plant species Opopanax hispidus has potential applications in modern medicine and diet, but it has been insufficiently studied. Different extraction methods were used to examine the chemical composition and biological potential of O. hispidus extracts, and it was found that extracts obtained by HAE had the highest content of bioactive compounds and antioxidant activity. Green extraction techniques were found to be more advantageous compared to conventional extraction methods. These extracts can be used as antioxidants, neuroprotectants, antityrosinase agents, and antidiabetic agents while following the principles of sustainable development and green chemistry.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Article
Biochemistry & Molecular Biology
Seom Lee, Chang Ha Park, Jin Kyung Kim, Kyungmin Ahn, Haejin Kwon, Jae Kwang Kim, Sang Un Park, Hyeon Ji Yeo
Summary: This study found that white LEDs are suitable for carotenoid production, while blue LEDs are efficient in increasing the accumulation of phenolics and their biological activities in kale microgreens.
Article
Plant Sciences
Tuba Acet, Cengiz Corbaci, Kadriye Ozcan
Summary: The study found that the extracts of Corydalis oppositifolia and Senecio cilicius have antimicrobial and radical scavenging activities, as well as high levels of flavonoids and phenolic acids. These plants and their extracts have the potential to be used in the treatment of diseases such as diabetes and Alzheimer's disease.
SOUTH AFRICAN JOURNAL OF BOTANY
(2021)
Article
Biochemistry & Molecular Biology
Dasha Mihaylova, Aneta Popova, Ivelina Desseva, Ivayla Dincheva, Yulian Tumbarski
Summary: Sustainability is becoming crucial in the field of food processing and technology, particularly in the characterization of food waste resources. This study provides information on the metabolites of peach peels using GC-MS, shedding light on their biological activities. The distribution patterns and contributions of chemical profile and phenolic compounds in peach peels of different Bulgarian varieties were investigated. The results suggest that free phenolics have the strongest potential, while the peels' extracts show limited ability to inhibit enzymes and moderate antimicrobial activity, indicating the need to find ways to utilize this waste.
Article
Biochemistry & Molecular Biology
Sezen Yilmaz Sarialtin, Ozlem Bahadir Acikara
Summary: This study analyzed the phytochemical content and biological activities of three endemic Scorzonera species in Turkey. The results showed that these plant extracts contained abundant flavonoids and caffeoylquinic acid derivatives, with higher amounts found in the aerial parts of S. coriacea. S. coriacea aerial parts exhibited the strongest inhibitory activities on ABTS and DPPH radicals.
CHEMISTRY & BIODIVERSITY
(2022)
Article
Chemistry, Multidisciplinary
Leilei Zhang, Gokhan Zengin, Gabriele Rocchetti, Ismail Senkardes, Jugreet B. Sharmeen, Mohamad Fawzi Mahomoodally, Tapan Behl, Youssef Rouphael, Luigi Lucini
Summary: In this study, extracts from Rhinanthus angustifolius subsp. grandiflorus were obtained using different extraction techniques and solvents, and evaluated for their antioxidant and enzyme-inhibiting properties. Methanol extracts showed the highest phenolic and flavonoid contents and radical-scavenging antioxidant capacity. Water extracts demonstrated the highest metal chelating activity. Additionally, the extracts showed different enzyme inhibition potentials, with water extracts exhibiting weaker inhibition. This suggests that R. angustifolius is a promising source of natural antioxidants and enzyme inhibitors for pharmaceutical purposes.
APPLIED SCIENCES-BASEL
(2021)
Article
Biochemistry & Molecular Biology
Ceren Emir, Gunes Coban, Ahmet Emir
Summary: This study analyzed the phenolic profiles of methanol extracts from wild Allium ampeloprasum. It found that 3-hydroxybenzoic acid was the major component, while quercetin and kaempferol were notable in certain samples. The study also evaluated the antioxidant activity and content of phenolic and flavonoid compounds, and found that the flowers of the samples had stronger enzyme inhibitory activity. Molecular modeling studies were conducted to understand the relationship between enzyme inhibition and phenolic components. These findings explore the potential usage of A. ampeloprasum in pharmaceutical and nutraceutical fields.
PROCESS BIOCHEMISTRY
(2022)
Article
Plant Sciences
Touka Letaief, Stefania Garzoli, Valentina Laghezza Masci, Jamel Mejri, Manef Abderrabba, Antonio Tiezzi, Elisa Ovidi
Summary: The Tunisian Ziziphus lotus plant was studied, revealing its phytoconstituents and biological activities. The methanolic extract of dried roots showed high levels of phenolics, flavonoids, and tannins, while the aqueous extract of roots exhibited the strongest antioxidant activity. Additionally, the cytotoxic activity against SH-SY5Y cell line was evaluated, with the petroleum ether and dichloromethane extracts of dried roots demonstrating significant activities.
Article
Chemistry, Applied
Shirley L. Sampaio, Spyridon A. Petropoulos, Maria Ines Dias, Carla Pereira, Ricardo C. Calhelha, Angela Fernandes, Camila M. M. Leme, Alexios Alexopoulos, Celestino Santos-Buelga, Isabel C. F. R. Ferreira, Lillian Barros
Summary: This study provides a detailed analysis of non-anthocyanin and anthocyanin phenolic compounds in potato peels from ten colored potato varieties, as well as a comprehensive evaluation of their antioxidant, cytotoxic, and anti-inflammatory potentials. The findings indicate that caffeic acid and caffeoylquinic acid were the most abundant non-anthocyanin phenolics in all samples, along with the presence of O-glycosylated flavonol derivatives and polyamine derivatives. Additionally, acylated anthocyanins were identified in red and purple varieties, with pelargonidin, peonidin, and malvidin being the most prominent aglycones detected. All samples demonstrated antioxidant and antitumor activities, with no observed toxicity, while the Rosemary variety exhibited the highest antioxidant and antitumor effects and was the only sample to show anti-inflammatory activity. These results have significant implications for the food industry in terms of utilizing potato peel as a natural ingredient in novel food and pharmaceutical formulations.
Article
Chemistry, Analytical
Gilda D'Urso, Paola Montoro, Sonia Piacente
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2020)
Article
Food Science & Technology
Paola Montoro, Gabriele Serreli, Katarzyna Angelika Gil, Gilda D'Urso, Adam Kowalczyk, Carlo Ignazio Giovanni Tuberoso
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2020)
Article
Biochemistry & Molecular Biology
Luigi De Masi, Paola Bontempo, Daniela Rigano, Paola Stiuso, Vincenzo Carafa, Angela Nebbioso, Sonia Piacente, Paola Montoro, Riccardo Aversano, Vincenzo D'Amelia, Domenico Carputo, Lucia Altucci
Article
Biochemistry & Molecular Biology
Gilda D'Urso, Jurriaan J. Mes, Paola Montoro, Robert D. Hall, Ric C. H. de Vos
Article
Multidisciplinary Sciences
Manuela Grimaldi, Angelica Palisi, Carmen Marino, Paola Montoro, Anna Capasso, Sara Novi, Mario Felice Tecce, Anna Maria D'Ursi
Article
Chemistry, Analytical
Alfredo Bottone, Paola Montoro, Milena Masullo, Cosimo Pizza, Sonia Piacente
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2020)
Article
Biochemistry & Molecular Biology
Paola Montoro, Gilda D'Urso, Adam Kowalczyk, Carlo Ignazio Giovanni Tuberoso
Summary: Through various complex analytical methods, the bitter component in strawberry tree honey was identified as unedone. This study provides important clues for identifying specific flavor substances in honey.
Article
Biochemistry & Molecular Biology
Monica R. Loizzo, Rosa Tundis, Mariarosaria Leporini, Gilda D'Urso, Rossella Gagliano Candela, Tiziana Falco, Sonia Piacente, Maurizio Bruno, Francesco Sottile
Summary: This study presents a model for reusing almond skin to formulate blackberry jam and investigates its phytochemical profile and bioactivity through various methods. The enriched jam shows antioxidant, hypoglycemic, and hypolipidemic effects, with increased activity after thermal processing.
Article
Food Science & Technology
Maria Assunta Crescenzi, Gilda D'Urso, Sonia Piacente, Paola Montoro
Summary: This study evaluated the potential of using food waste as a source of bioactive metabolites through metabolomic analysis, focusing on fennel waste and identifying various beneficial compounds with anti-inflammatory, antioxidant, and/or immunomodulatory properties. The presence of unique metabolites, such as oxylipins, in fennel waste was also discovered. These findings suggest that food waste could serve as a valuable resource for producing cosmetic and nutraceutical products with bioactive compounds.
Article
Biochemistry & Molecular Biology
Maria Assunta Crescenzi, Gilda D'Urso, Sonia Piacente, Paola Montoro
Summary: Fennel waste, particularly the little stem and leaf, contains bioactive compounds with promising anti-inflammatory activities. Phenolic acids and glycosylated flavonoids are key metabolites that have the ability to inhibit COX-2. Fennel leaf, therefore, should be included in nutraceuticals or functional foods for human consumption due to its potential health benefits.
Article
Biochemistry & Molecular Biology
Maria Assunta Crescenzi, Gilda D'Urso, Sonia Piacente, Paola Montoro
Summary: Seasonality is a crucial environmental factor affecting the metabolome of a plant, thereby leading to variations in the content of metabolites and their biological properties. This study quantified biologically active compounds in F. vulgare waste obtained during different seasons and found that the summer-grown Preludio variety had a higher content of bioactive compounds, resulting in better antioxidant power.
Article
Biochemistry & Molecular Biology
Angela Fadda, Paola Montoro, Gilda D'Urso, Nicoletta Ravasio, Federica Zaccheria, Daniele Sanna
Summary: Bio-based, non-toxic and biodegradable solvents and mechanical extraction were used to extract phenolic-rich oils from myrtle seeds. The oils had different yields, peroxide values, lipid compositions, and total phenolic concentrations depending on the extraction methods and myrtle varieties. The oxidative stability of the oils and the role of phenolic compounds in radical species evolution were also studied.
Article
Plant Sciences
Luigi d'Aquino, Rosaria Cozzolino, Giovanni Nardone, Gianni Borelli, Emilia Gambale, Maria Sighicelli, Patrizia Menegoni, Giuseppe Carlo Modarelli, Juri Rimauro, Elena Chianese, Giuseppe Nenna, Tommaso Fasolino, Gilda D'Urso, Paola Montoro
Summary: The indoor cultivation of basil using artificial lighting is gaining interest. This study compared the effects of white and blue-red light on plant growth, photochemistry, nutrient concentration, and secondary metabolism. The plants grown under white light showed better growth and biomass production compared to those grown under blue-red light. Both light conditions had different effects on nutrient concentration and translocation rate, and no photosynthetic stress was observed. However, leaves grown under white light had higher levels of maximum quantum yield of PSII and electron transport rate. Differences in metabolic patterns, especially phenolic compound concentrations, were detected under the two lighting conditions.
