Review
Biochemistry & Molecular Biology
Marie Closset, Katia Cailliau, Sylvain Slaby, Matthieu Marin
Summary: This review compiles scientific data on the neurotoxicity of aluminium contamination on the nervous system of aquatic organisms, highlighting its potential effects such as oxidative stress, changes in acetylcholinesterase activity, and neurotransmitter levels. However, the impacts of aluminium exposure on the early stages of aquatic vertebrate development are poorly described.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
M. Dolores Molina, Dema Abduljabbar, Anna Guixeras, Susanna Fraguas, Francesc Cebria
Summary: This study reports the complete repertoire of LIM-HD genes in Schmidtea mediterranea. The results show that these genes play crucial roles in the cephalic ganglia, digestive system, and regeneration of planarians, controlling the restoration and maintenance of cell identity and patterning.
Review
Cell Biology
Carmen Falcone
Summary: The central nervous system (CNS) in vertebrates exhibits incredible diversity at multiple levels. Astrocytes, a type of glial cell, play a crucial role in regulating various features of the CNS, but their definition and research in vertebrates are still limited. This article elucidates the current understanding of astrocytes and astrocyte-like cells in vertebrates, expanding our knowledge of their evolution and relevance to the structure and function of the vertebrate brain.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Review
Neurosciences
Maria Vitoria Nava Moura, Gabriel Mesquita da Conceicao Bahia, Marcio Goncalves Correa, Maiza Amanda Araujo Sarges, Thais Alves Lobao, Erica Miranda Sanches, Karen R. H. Matos Oliveira, Anderson Manoel Herculano, Carlomagno Pacheco Bahia
Summary: This systematic review investigated the neuroprotective effects of crude extracts, compounds, and isolated molecules obtained from plants on central nervous system injuries. The results showed promising effects on brain and spinal cord, including antioxidant activity improvement, inflammatory response modulation, tissue preservation, and motor and cognitive recovery.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Laurence A. Lemaire, Chen Cao, Peter H. Yoon, Juanjuan Long, Michael Levine
Summary: By studying the brain maps of swimming tadpoles of Ciona, researchers have identified cell types and functional regions associated with the vertebrate hypothalamus, providing evidence that the hypothalamus predates the evolution of the vertebrate brain.
Article
Chemistry, Multidisciplinary
Wenqiang Ding, Shuang Wang, Jiaxiang Gu, Lei Yu
Summary: Selenium functions as selenoprotein in the human body, with the brain being one of the most abundant organs of selenoprotein. It plays a crucial role in maintaining brain redox homeostasis, regulating signal transduction pathways, and neuroimmune regulation. Nano-selenium has attracted attention due to its high bioavailability and low toxicity, and it has great potential in biomedical applications for the nervous system. Recent research on selenoprotein and nano-selenium has become a new focus in understanding the important functions of selenium in the human nervous system.
CHINESE CHEMICAL LETTERS
(2023)
Article
Mathematics
Mohammed Balubaid, Osman Taylan, Mustafa Tahsin Yilmaz, Ehsan Eftekhari-Zadeh, Ehsan Nazemi, Mohammed Alamoudi
Summary: The Central Nervous System (CNS) is a vital part of the nervous system that comprises the brain and spinal cord. Researchers have proposed a modified version of a neuronal model using a quadratic-based modeling called Digital Spiking Silicon Neuron (DSSN), which can imitate the basic behaviors of the original model. The hardware implementation of the new model shows high similarity with the original model in terms of neuronal behaviors, as well as achieving higher frequency and lower cost conditions.
Article
Behavioral Sciences
Juliet L. Kroll, Thomas Ritz
Summary: Accumulating behavioral evidence suggests that asthma is associated with cognitive deficits. A literature review was conducted to identify studies examining potential central nervous system (CNS) contributions to cognition in asthma. The review discusses the general understanding of the CNS in asthma, proposes a working model linking neural influences of asthma pathology with cognition, and highlights the clinical significance of CNS and neurocognitive sequelae in asthma.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Biochemistry & Molecular Biology
Adele Leggieri, Chiara Attanasio, Antonio Palladino, Paolo de Girolamo, Carla Lucini, Livia D'Angelo
Summary: This study investigates the age-dependent regulation of col4a1 and col25a1 in the brain of Nothobranchius furzeri and reveals their increased expression during aging. The findings also suggest a difference in the expression patterns of col4a1 and col25a1 between this species and mammals. These results encourage further research on the role of these collagen proteins in the biology of the vertebrate brain, aging, and neurodegenerative diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Oncology
Kimberly D. Miller, Quinn T. Ostrom, Carol Kruchko, Nirav Patil, Tarik Tihan, Gino Cioffi, Hannah E. Fuchs, Kristin A. Waite, Ahmedin Jemal, Rebecca L. Siegel, Jill S. Barnholtz-Sloan
Summary: Brain and other CNS tumors are highly fatal cancers in the United States, with different incidence rates and survival rates among different races and age groups. Survival disparities, especially in childhood tumors, highlight the importance of providing more resources to advance research and understand the reasons behind differences in brain tumor occurrence, especially among rarer subtypes and understudied populations.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)
Review
Pharmacology & Pharmacy
Ko-Ting Chen, Kuo-Chen Wei, Hao-Li Liu
Summary: Focused ultrasound combined with microbubbles enables precise, transient, reversible, and noninvasive opening of the blood-brain barrier. This technology enhances the penetration of therapeutic agents in the central nervous system, while also modulating local immunity and neuronal activity.
Review
Biochemistry & Molecular Biology
Tinh Thi Nguyen, Peter Baumann, Oliver Tuescher, Sandra Schick, Kristina Endres
Summary: The gut and the brain communicate through various channels and interactions, collectively known as the gut-brain axis. The aging of the enteric nervous system (ENS) in the gut can lead to gastrointestinal dysfunction and contribute to age-related diseases of the brain. Understanding the mechanisms of the aging ENS can provide insights into the diagnosis and treatment of neurodegenerative diseases like Alzheimer's and Parkinson's.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Nanoscience & Nanotechnology
Tianyou Liu, Qinglian Xie, Zaiquan Dong, Qiang Peng
Summary: The treatment of central nervous system disorders is challenging due to the presence of the blood-brain barrier (BBB). Nanoparticles-based drug delivery systems have shown great potential in overcoming the BBB and treating CNS diseases. This article summarizes the recent progress in nanoparticles-based systems for CNS delivery and discusses the prerequisites, drawbacks, and challenges of nanocarriers in this field, such as protein corona formation.
Article
Biodiversity Conservation
Quansheng Fu, Xianhan Huang, Jacob B. Landis, Pengju Liu, Lijuan Li, Zhenyu Lv, Juntong Chen, Hengchang Wang, Jiahui Chen, Xuelong Jiang, Yi Jin, Hang Sun, Tao Deng
Summary: The study found that in Yunnan Province, China, family size is a good predictor of extinction risk among vascular plants and terrestrial vertebrates. Extinction risk is related to evolutionary history at the family level.
GLOBAL ECOLOGY AND CONSERVATION
(2021)
Article
Engineering, Environmental
Zhiling Wu, Xianchun Tang, Hongbin Chen
Summary: Research on invertebrates in drinking water demonstrated that their abundance and taxa are influenced by seasonality and treatment processes, with rotifers, nematodes, and crustaceans being dominant. Efficient removal of invertebrates was observed in the sedimentation tank, but more propagation and leakage occurred in the sand and BAC filters, particularly in the latter. The proportion of endogenous invertebrates gradually increased along the treatment process.
FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
One R. Pagan, Erica Montgomery, Sean Deats, Daniel Bach, Debra Baker
NEUROCHEMICAL RESEARCH
(2015)
Article
Neurosciences
Daniel J. Bach, Matthew Tenaglia, Debra L. Baker, Sean Deats, Erica Montgomery, One R. Pagan
NEUROSCIENCE LETTERS
(2016)
Article
Developmental Biology
One R. Pagan
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
(2017)
Article
Neurosciences
David Schwarz, Damaris Bloom, Rocio Castro, One R. Pagan, C. A. Jimenez-Rivera
CURRENT NEUROPHARMACOLOGY
(2011)
Article
Pharmacology & Pharmacy
Amanda L. Rowlands, One R. Pagan
EUROPEAN JOURNAL OF PHARMACOLOGY
(2008)
Article
Pharmacology & Pharmacy
One R. Pagan, Amanda L. Rowlands, Angela L. Fattore, Tamara Coudron, Kimberly R. Urban, Apurva H. Bidja, Vesna A. Eterovic
EUROPEAN JOURNAL OF PHARMACOLOGY
(2009)
Article
Developmental Biology
One R. Pagan, Debra Baker, Sean Deats, Erica Montgomery, Matthew Tenaglia, Clinita Randolph, Dharini Kotturu, Christopher Tallarida, Daniel Bach, Galia Wilk, Scott Rawls, Robert B. Raffa
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
(2012)
Article
Biochemistry & Molecular Biology
Kannan Sivaprakasam, One R. Pagan, George P. Hess
JOURNAL OF MEMBRANE BIOLOGY
(2010)
Article
Neurosciences
O. R. Pagan, S. Deats, D. Baker, E. Montgomery, G. Wilk, M. Tenaglia, J. Semon
Article
Behavioral Sciences
One R. Pagan, Amanda L. Rowlands, Mahrukh Azam, Kimberly R. Urban, Apurva H. Bidja, Danielle M. Roy, Ryan B. Feeney, Lilly K. Afshari
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2008)
Article
Behavioral Sciences
Debra Baker, Sean Deats, Peter Boor, James Pruitt, One R. Pagan
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2011)
Article
Pharmacology & Pharmacy
P. A. Ferchmin, One R. Pagan, Henning Ulrich, Ada C. Szeto, Richard M. Hann, Vesna A. Eterovic
Article
Neurosciences
One R. Pagan, Kannan Sivaprakasam, Robert E. Oswald
JOURNAL OF NEUROSCIENCE RESEARCH
(2007)
Article
Neurosciences
One R. Pagan, Amanda L. Rowlands, Kimberly R. Urban
NEUROSCIENCE LETTERS
(2006)