The clinical application of gene editing: ethical and social issues

Gene therapy for sickle cell disease: An update

(2018) Selami Demirci et al.   CYTOTHERAPY

Gene modification therapies: views of parents of people with Down syndrome

(2018) Marsha Michie et al.   GENETICS IN MEDICINE

A need for better understanding is the major determinant for public perceptions of human gene editing.

(2018) Tristan McCaughey et al.   HUMAN GENE THERAPY

Survey on the perception of germline genome editing among the general public in Japan

(2018) Masato Uchiyama et al.   JOURNAL OF HUMAN GENETICS

Genome editing to 're-write' wrongs

(2018) Mary Ellen Perry et al.   NATURE REVIEWS DRUG DISCOVERY

Stakeholder-driven, consensus development methods to design an ethical framework and guidelines for engaged research

(2018) Giselle Corbie-Smith et al.   PLoS One

Gene therapy comes of age

(2018) Cynthia E. Dunbar et al.   SCIENCE

Hurdles in gene therapy regulatory approval: a retrospective analysis of European Marketing Authorization Applications

(2018) Marta Carvalho et al.   DRUG DISCOVERY TODAY

A CRISPR focus on attitudes and beliefs toward somatic genome editing from stakeholders within the sickle cell disease community

(2018) Anitra Persaud et al.   GENETICS IN MEDICINE

How the genome-edited babies revelation will affect research

(2018) David Cyranoski et al.   NATURE

In utero CRISPR-mediated therapeutic editing of metabolic genes

(2018) Avery C. Rossidis et al.   NATURE MEDICINE

One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans

(2017) Heidi C. Howard et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Transferring embryos with genetic anomalies detected in preimplantation testing: an Ethics Committee Opinion

(2017) Judith Daar et al.   FERTILITY AND STERILITY

Genome editing in clinical genetics: points to consider—a statement of the American College of Medical Genetics and Genomics

(2017) ACMG Board of Directors   GENETICS IN MEDICINE

Impairment Experiences, Identity and Attitudes Towards Genetic Screening: the Views of People with Spinal Muscular Atrophy

(2017) Felicity K. Boardman et al.   Journal of Genetic Counseling

Correction of a pathogenic gene mutation in human embryos

(2017) Hong Ma et al.   NATURE

Gene Therapy in a Patient with Sickle Cell Disease

(2017) Jean-Antoine Ribeil et al.   NEW ENGLAND JOURNAL OF MEDICINE

What Do We Really Think About Human Germline Genome Editing, and What Does It Mean for Medicine?

(2017) Kiran Musunuru et al.   Circulation-Cardiovascular Genetics

The science of stakeholder engagement in research: classification, implementation, and evaluation

(2017) Melody S. Goodman et al.   Translational Behavioral Medicine

Should you edit your children’s genes?

(2016) Erika Check Hayden   NATURE

Genome editing comes of age

(2016) Jin-Soo Kim   Nature Protocols

Editing policy to fit the genome?

(2016) R. Isasi et al.   SCIENCE

Family and professionals underestimate quality of life across diverse cultures and health conditions: systematic review

(2015) Thomas F. Crocker et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

CCR5 deficiency predisposes to fatal outcome in influenza virus infection

(2015) A. Falcon et al.   JOURNAL OF GENERAL VIROLOGY

Oversight of human inheritable genome modification

(2015) Rosario Isasi et al.   NATURE BIOTECHNOLOGY

Brave New Genome

(2015) Eric S. Lander   NEW ENGLAND JOURNAL OF MEDICINE

TALEN-Mediated Gene Mutagenesis in Rhesus and Cynomolgus Monkeys

(2014) Hailiang Liu et al.   Cell Stem Cell

Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing

(2014) Qiurong Ding et al.   CIRCULATION RESEARCH

The expressivist objection to prenatal testing: The experiences of families living with genetic disease

(2014) Felicity Kate Boardman   SOCIAL SCIENCE & MEDICINE

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

(2013) Hui Yang et al.   CELL

What does it mean to be genomically literate?: National Human Genome Research Institute Meeting Report

(2013) Belen Hurle et al.   GENETICS IN MEDICINE

ASSESSING THE IMPACTS OF CITIZEN DELIBERATIONS ON THE HEALTH TECHNOLOGY PROCESS

(2013) Julia Abelson et al.   INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE

Global Burden of Sickle Cell Anaemia in Children under Five, 2010–2050: Modelling Based on Demographics, Excess Mortality, and Interventions

(2013) Frédéric B. Piel et al.   PLOS MEDICINE

Having a son or daughter with Down syndrome: Perspectives from mothers and fathers

(2011) Brian G. Skotko et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Self-perceptions from people with Down syndrome

(2011) Brian G. Skotko et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Having a brother or sister with Down syndrome: Perspectives from siblings

(2011) Brian G. Skotko et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Chemokine control of West Nile virus infection

(2011) Jean K. Lim et al.   EXPERIMENTAL CELL RESEARCH

Eliciting ethical and social values in health technology assessment: A participatory approach

(2011) Yvonne Bombard et al.   SOCIAL SCIENCE & MEDICINE

With new prenatal testing, will babies with Down syndrome slowly disappear?

(2009) B. G Skotko   ARCHIVES OF DISEASE IN CHILDHOOD

Genetic selection for deafness: the views of hearing children of deaf adults

(2009) C Mand et al.   JOURNAL OF MEDICAL ETHICS

Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

(2009) Aron M. Geurts et al.   SCIENCE

‘You Say You’re Happy, but…’: Contested Quality of Life Judgments in Bioethics and Disability Studies

(2008) Sara Goering   Journal of Bioethical Inquiry