Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury from Oxidative Stress by Regulating Succinate, Lysophospholipid Metabolism, and ROS Scavenging System

2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation

(2017) Borja Ibanez et al.   EUROPEAN HEART JOURNAL

Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species

(2017) Mary Board et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Astragaloside IV for Experimental Focal Cerebral Ischemia: Preclinical Evidence and Possible Mechanisms

(2017) Hui-Lin Wang et al.   Oxidative Medicine and Cellular Longevity

Comprehensive metabolomics identified lipid peroxidation as a prominent feature in human plasma of patients with coronary heart diseases

(2017) Jianhong Lu et al.   Redox Biology

Therapies targeting lipid peroxidation in traumatic brain injury

(2016) Tamil Selvan Anthonymuthu et al.   BRAIN RESEARCH

Succinate metabolism: a new therapeutic target for myocardial reperfusion injury

(2016) Victoria R. Pell et al.   CARDIOVASCULAR RESEARCH

Choline and dimethylglycine produce superoxide/hydrogen peroxide from the electron transport chain in liver mitochondria

(2016) Ryan J. Mailloux et al.   FEBS LETTERS

Comprehensive Metabolomic Characterization of Coronary Artery Diseases

(2016) Yong Fan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Metabolic Alterations Induce Oxidative Stress in Diabetic and Failing Hearts: Different Pathways, Same Outcome

(2015) David Roul et al.   ANTIOXIDANTS & REDOX SIGNALING

Global and Regional Patterns in Cardiovascular Mortality From 1990 to 2013

(2015) Gregory A. Roth et al.   CIRCULATION

Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice

(2015) Wei-Jian Zhang et al.   MEDIATORS OF INFLAMMATION

Astragaloside IV inhibits migration and invasion in human lung cancer A549 cells via regulating PKC-α-ERK1/2-NF-κB pathway

(2014) Xudong Cheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

HIF-1α Signaling Activation by Post-Ischemia Treatment with Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury

(2014) Jingwen Si et al.   PLoS One

Astragaloside IV prevents acute kidney injury in two rodent models by inhibiting oxidative stress and apoptosis pathways

(2013) Dingkun Gui et al.   APOPTOSIS

Myocardial Conditioning

(2013) Michel Ovize et al.   CIRCULATION RESEARCH

Astragaloside IV protects heart from ischemia and reperfusion injury via energy regulation mechanism

(2013) Lei Tu et al.   MICROCIRCULATION

Astragaloside IV Stimulates Angiogenesis and Increases Nitric Oxide Accumulation via JAK2/STAT3 and ERK1/2 Pathway

(2013) Shi-Guang Wang et al.   MOLECULES

The innate immune response in reperfused myocardium

(2012) L. Timmers et al.   CARDIOVASCULAR RESEARCH

Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis

(2012) Ralf Gold et al.   NEW ENGLAND JOURNAL OF MEDICINE

Astragaloside IV Inhibits Oxidative Stress-Induced Mitochondrial Permeability Transition Pore Opening by Inactivating GSK-3βvia Nitric Oxide in H9c2 Cardiac Cells

(2012) Yonggui He et al.   Oxidative Medicine and Cellular Longevity

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Effect of astragaloside IV on hepatic glucose-regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin

(2009) Lin Lv et al.   PHYTOTHERAPY RESEARCH

Dichloromethane as a Solvent for Lipid Extraction and Assessment of Lipid Classes and Fatty Acids from Samples of Different Natures

(2008) Elena Cequier-Sánchez et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

(2008) T. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Measurement of ischaemia-reperfusion in patients with intermittent claudication using NMR-based metabonomics

(2008) Stefan A. Coolen et al.   NMR IN BIOMEDICINE