SOD1 is essential for oncogene-driven mammary tumor formation but dispensable for normal development and proliferation

Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma

(2018) Shuai Li et al.   Cell Communication and Signaling

SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation

(2018) Chi Kwan Tsang et al.   MOLECULAR CELL

Sex specific activation of the ERα axis of the mitochondrial UPR (UPRmt) in the G93A-SOD1 mouse model of familial ALS

(2017) Amanjot K Riar et al.   HUMAN MOLECULAR GENETICS

Toward the identification and the targeting of key players of the mitochondrial unfolded protein response (UPRmt) in cancer

(2017) Doris Germain   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

From discovery of the CHOP axis and targeting ClpP to the identification of additional axes of the UPRmt driven by the estrogen receptor and SIRT3

(2017) Timothy C. Kenny et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasis

(2017) T C Kenny et al.   ONCOGENE

The Mitochondrial Unfolded Protein Response as a Non-Oncogene Addiction to Support Adaptation to Stress during Transformation in Cancer and Beyond

(2017) Timothy C. Kenny et al.   Frontiers in Oncology

SOD2 and the Mitochondrial UPR: Partners Regulating Cellular Phenotypic Transitions

(2016) Chenxia He et al.   TRENDS IN BIOCHEMICAL SCIENCES

MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer

(2015) Peter C. Hart et al.   Nature Communications

Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells

(2015) Babu V. Sajesh et al.   Oncotarget

Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research

(2015) Norman Moullan et al.   Cell Reports

HER2-family signalling mechanisms, clinical implications and targeting in breast cancer

(2014) N. Elster et al.   BREAST CANCER RESEARCH AND TREATMENT

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

SOD2 to SOD1 Switch in Breast Cancer

(2014) Luena Papa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets

(2014) N. Kannan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiation Induces Diffusible Feeder Cell Factor(s) That Cooperate with ROCK Inhibitor to Conditionally Reprogram and Immortalize Epithelial Cells

(2013) Nancy Palechor-Ceron et al.   AMERICAN JOURNAL OF PATHOLOGY

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration

(2013) Amit R. Reddi et al.   CELL

Targeting SOD1 reduces experimental non–small-cell lung cancer

(2013) Andrea Glasauer et al.   JOURNAL OF CLINICAL INVESTIGATION

SirT3 Regulates the Mitochondrial Unfolded Protein Response

(2013) L. Papa et al.   MOLECULAR AND CELLULAR BIOLOGY

Manganese Superoxide Dismutase (Sod2) and Redox-Control of Signaling Events That Drive Metastasis

(2012) Nadine Hempel et al.   Anti-Cancer Agents in Medicinal Chemistry

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

Estrogen receptor mediates a distinct mitochondrial unfolded protein response

(2011) L. Papa et al.   JOURNAL OF CELL SCIENCE

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines

(2011) R. Somwar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

(2010) F. Weinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT