Synthesis of 4,5-disubstituted-1H-1,2,3-triazoles

Click chemistry based multicomponent approach in the synthesis of spirochromenocarbazole tethered 1,2,3-triazoles as potential anticancer agents

(2019) Pramod V. Chavan et al.   BIOORGANIC CHEMISTRY

Recent Advancements in 1,4-Disubstituted 1H-1,2,3-Triazoles as Potential Anticancer Agents

(2018) Kashmiri Lal et al.   Anti-Cancer Agents in Medicinal Chemistry

Metal-free site selective cross-coupling of pyridines with secondary phosphine chalcogenides using acylacetylenes as oxidants

(2018) Boris A. Trofimov et al.   CHEMICAL COMMUNICATIONS

Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer

(2018) Andrea Bistrović et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel triazoles of 3-acetylbetulin and betulone as anticancer agents

(2018) Ewa Bębenek et al.   MEDICINAL CHEMISTRY RESEARCH

A Mild Multi-Component Reaction for the Synthesis of 4,5-Disubstituted 1H-1,2,3-Triazoles from Phosphonium Salts, Aldehydes, and Sodium Azide

(2018) Qin-Pei Wu et al.   SYNTHESIS-STUTTGART

Mechanism of copper-free Sonogashira reaction operates through palladium-palladium transmetallation

(2018) Martin Gazvoda et al.   Nature Communications

Novel pyrimidine-2,4-dione–1,2,3-triazole and furo[2,3-d]pyrimidine-2-one–1,2,3-triazole hybrids as potential anti-cancer agents: Synthesis, computational and X-ray analysis and biological evaluation

(2017) Tomislav Gregorić et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A rapid synthesis of 2-substituted 1,2,3- triazole-1-oxide derivative starting from 4-(methyl)isonitrosoacetophenone and its Ni(II) complex: Characterization, DNA binding and cleavage properties

(2017) Ramazan Gup et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis of tetrafluoroethylene- and tetrafluoroethyl-containing azides and their 1,3-dipolar cycloaddition as synthetic application

(2017) Svatava Voltrová et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Design, synthesis and biological evaluation of ciprofloxacin tethered bis-1,2,3-triazole conjugates as potent antibacterial agents

(2016) Rama Kant et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of water soluble chitosan derivatives with halogeno-1,2,3-triazole and their antifungal activity

(2016) Qing Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Highly Efficient Cycloaddition Reaction of 1,3-Diynes with Sodium Azide: A New Way to 5-Substituted-4-acetylene-1H-1,2,3-triazoles

(2016) Jia-Liang Tang et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Pd-catalyzed ligand-free C(5)–H arylation of 1,4-disubstituted 1,2,3-triazoles promoted by microwaves

(2016) Fen Zhao et al.   SYNTHETIC COMMUNICATIONS

Synthesis, anti-inflammatory, bactericidal activities and docking studies of novel 1,2,3-triazoles derived from ibuprofen using click chemistry

(2016) Kishore Kumar Angajala et al.   SpringerPlus

Design and synthesis of novel 1,2,3-triazole–pyrimidine–urea hybrids as potential anticancer agents

(2015) Li-Ying Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluation of novel 4,5-disubstituted 2H-1,2,3-triazoles as cis-constrained analogues of combretastatin A-4

(2015) Nikhil R. Madadi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

(E)-2-(4-Arylbut-1-en-3-yn-1-yl)chromones as Synthons for the Synthesis of Xanthone-1,2,3-triazole Dyads

(2015) Hélio M. T. Albuquerque et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Peptide Triazole Inactivators of HIV-1 Utilize a Conserved Two-Cavity Binding Site at the Junction of the Inner and Outer Domains of Env gp120

(2015) Rachna Aneja et al.   JOURNAL OF MEDICINAL CHEMISTRY

One-Pot, Three-Component Reaction Using Modified Julia Reagents: A Facile Synthesis of 4,5-Disubstituted 1,2,3-(NH)-Triazoles in a Wet Organic Solvent

(2015) Huihui Chai et al.   ACS Combinatorial Science

Beyond click chemistry – supramolecular interactions of 1,2,3-triazoles

(2014) Benjamin Schulze et al.   CHEMICAL SOCIETY REVIEWS

Calamitic liquid crystals of 1,2,3-triazole connected to azobenzene: synthesis, characterisation and anisotropic properties

(2014) Subramanian Balamurugan et al.   LIQUID CRYSTALS

Aryl-palladium-NHC complex: efficient phosphine-free catalyst precursors for the carbonylation of aryl iodides with amines or alkynes

(2014) Chunyan Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Click Chemistry for Drug Development and Diverse Chemical–Biology Applications

(2013) Prakasam Thirumurugan et al.   CHEMICAL REVIEWS

Palladium-, ligand-, and solvent-free synthesis of ynones by the coupling of acyl chlorides and terminal alkynes in the presence of a reusable copper nanoparticle catalyst

(2013) Weijiang Sun et al.   GREEN CHEMISTRY

Click Chemistry in Peptide-Based Drug Design

(2013) Huiyuan Li et al.   MOLECULES

Microwave-Assisted Azide-Alkyne Cycloaddition in Water Using a Heterogeneous Cu-Catalyst

(2013) Katharina Jacob et al.   SYNTHETIC COMMUNICATIONS

Catalytic activity of palladium acyclic diaminocarbene complexes in the synthesis of 1,3-diarylpropynones via Sonogashira reaction: cross- versus homo-coupling

(2013) Dmitry S. Ryabukhin et al.   TETRAHEDRON LETTERS

Dual-functional click-triazole: a metal chelator and immobilization linker for the construction of a heterogeneous palladium catalyst and its application for the aerobic oxidation of alcohols

(2012) Guofu Zhang et al.   CHEMICAL COMMUNICATIONS

A highly active magnetically recoverable nano ferrite-glutathione-copper (nano-FGT-Cu) catalyst for Huisgen 1,3-dipolar cycloadditions

(2012) R. B. Nasir Baig et al.   GREEN CHEMISTRY

Click Dendrimers and Triazole-Related Aspects: Catalysts, Mechanism, Synthesis, and Functions. A Bridge between Dendritic Architectures and Nanomaterials

(2011) Didier Astruc et al.   ACCOUNTS OF CHEMICAL RESEARCH

Click Chemistry Finds Its Way into Covalent Porous Organic Materials

(2011) Thierry Muller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 1,2,3-Triazole-Fused Heterocycles via Intramolecular Azide-Alkyne Cycloaddition Reactions

(2011) Krishna Majumdar et al.   SYNTHESIS-STUTTGART

Tandem Knoevenagel-[3+2] cycloaddition-elimination reactions: one-pot synthesis of 4,5-disubstituted 1,2,3-(NH)-triazoles

(2011) Thanasekaran Ponpandian et al.   TETRAHEDRON LETTERS

Synthesis and cytotoxicity evaluation of novel 1,4-disubstituted 1,2,3-triazoles via CuI catalysed 1,3-dipolar cycloaddition

(2010) Jyothi Vantikommu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Facile One-Pot Synthesis of 4,5-Disubstituted 1,2,3-(NH)-Triazoles through Sonogashira Coupling/1,3-Dipolar Cycloaddition of Acid Chlorides, Terminal Acetylenes, and Sodium Azide

(2009) Jihui Li et al.   ORGANIC LETTERS

Microwave dielectric heating in synthetic organic chemistry

(2008) C. Oliver Kappe   CHEMICAL SOCIETY REVIEWS

Copper-FreeSonogashira Coupling of Acid Chlorides with Terminal Alkynes in the Presence of a Reusable Palladium Catalyst: An Improved Synthesis of 3-Iodochromenones (=3-Iodo-4H-1-benzopyran-4-ones)

(2008) Pravin R. Likhar et al.   HELVETICA CHIMICA ACTA

Construction of Linear Polymers, Dendrimers, Networks, and Other Polymeric Architectures by Copper‐Catalyzed Azide‐Alkyne Cycloaddition “Click” Chemistry

(2008) Jeremiah A. Johnson et al.   MACROMOLECULAR RAPID COMMUNICATIONS