Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

Translating Immunopeptidomics to Immunotherapy-Decision-Making for Patient and Personalized Target Selection

(2018) Jens Fritsche et al.   PROTEOMICS

Actively personalized vaccination trial for newly diagnosed glioblastoma

(2018) Norbert Hilf et al.   NATURE

The Human Leukocyte Antigen (HLA)-B27 Peptidomein Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion

(2017) Eilon Barnea et al.   MOLECULAR & CELLULAR PROTEOMICS

Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens

(2017) Michael S. Khodadoust et al.   NATURE

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

Tumor Vaccines for Malignant Gliomas

(2017) Visish M. Srinivasan et al.   Neurotherapeutics

The immunopeptidomic landscape of ovarian carcinomas

(2017) Heiko Schuster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Data-Independent Acquisition of HLA Class I Peptidomes on the Q Exactive Mass Spectrometer Platform

(2017) Danilo Ritz et al.   PROTEOMICS

Building proteomic tool boxes to monitor MHC class I and class II peptides

(2017) Frances-Rose Schumacher et al.   PROTEOMICS

Phenotypic Analysis of Organoids by Proteomics

(2017) Alexis Gonneaud et al.   PROTEOMICS

Immunological Aspects of Malignant Gliomas

(2016) Or Cohen-Inbar et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

The Basis of Oncoimmunology

(2016) A. Karolina Palucka et al.   CELL

Mass spectrometry-based antigen discovery for cancer immunotherapy

(2016) Michal Bassani-Sternberg et al.   CURRENT OPINION IN IMMUNOLOGY

Recent advances and future of immunotherapy for glioblastoma

(2016) Neha Kamran et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

MHC class I–associated peptides derive from selective regions of the human genome

(2016) Hillary Pearson et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Leukocyte Antigen (HLA) B27 Allotype-Specific Binding and Candidate Arthritogenic Peptides Revealed through Heuristic Clustering of Data-independent Acquisition Mass Spectrometry (DIA-MS) Data

(2016) Ralf B. Schittenhelm et al.   MOLECULAR & CELLULAR PROTEOMICS

Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy

(2016) Bracha Shraibman et al.   MOLECULAR & CELLULAR PROTEOMICS

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

High-sensitivity HLA class I peptidome analysis enables a precise definition of peptide motifs and the identification of peptides from cell lines and patients’ sera

(2016) Danilo Ritz et al.   PROTEOMICS

Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

(2016) Michal Bassani-Sternberg et al.   Nature Communications

Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens

(2016) Shelly Kalaora et al.   Oncotarget

Carcinogenesis of renal cell carcinoma reflected in HLA ligands: A novel approach for synergistic peptide vaccination design

(2016) Martin G. Klatt et al.   OncoImmunology

The antigenic landscape of multiple myeloma: mass spectrometry (re)defines targets for T-cell-based immunotherapy

(2015) S. Walz et al.   BLOOD

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

The nature of self for T cells—a systems-level perspective

(2015) Diana P Granados et al.   CURRENT OPINION IN IMMUNOLOGY

Concepts of immunotherapy for glioma

(2015) Mira A. Patel et al.   JOURNAL OF NEURO-ONCOLOGY

Simultaneous Quantification of Viral Antigen Expression Kinetics Using Data-Independent (DIA) Mass Spectrometry

(2015) Nathan P. Croft et al.   MOLECULAR & CELLULAR PROTEOMICS

Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

(2015) Michal Bassani-Sternberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Analysis of Major Histocompatibility Complex (MHC) Immunopeptidomes Using Mass Spectrometry

(2015) Etienne Caron et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantifying epitope presentation using mass spectrometry

(2015) Nathan P. Croft et al.   MOLECULAR IMMUNOLOGY

BioGPS: building your own mash-up of gene annotations and expression profiles

(2015) Chunlei Wu et al.   NUCLEIC ACIDS RESEARCH

Glioblastoma multiforme: Pathogenesis and treatment

(2015) Constantinos Alifieris et al.   PHARMACOLOGY & THERAPEUTICS

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Ventromedial hypothalamic neurons control a defensive emotion state

(2015) Prabhat S Kunwar et al.   eLife

Trial Watch: Peptide-based anticancer vaccines

(2015) Jonathan Pol et al.   OncoImmunology

Immunotherapeutic Advancements for Glioblastoma

(2015) Leonel Ampie et al.   Frontiers in Oncology

Cost-efficient high-throughput HLA typing by MiSeq amplicon sequencing

(2014) Vinzenz Lange et al.   BMC GENOMICS

Epidemiologic and Molecular Prognostic Review of Glioblastoma

(2014) J. P. Thakkar et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Vaccine Therapies in Malignant Glioma

(2014) Taemin Oh et al.   Current Neurology and Neuroscience Reports

Peptide vaccines for the treatment of glioblastoma

(2014) Adam M. Swartz et al.   JOURNAL OF NEURO-ONCOLOGY

The nature and extent of contributions by defective ribosome products to the HLA peptidome

(2014) D. Bourdetsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HLA ligandome analysis identifies the underlying specificities of spontaneous antileukemia immune responses in chronic lymphocytic leukemia (CLL)

(2014) Daniel J. Kowalewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cause and Consequence of Cancer/Testis Antigen Activation in Cancer

(2013) Angelique W. Whitehurst   Annual Review of Pharmacology and Toxicology

HLA ligandome tumor antigen discovery for personalized vaccine approach

(2013) Hans-Georg Rammensee et al.   Expert Review of Vaccines

HLA Class I Alleles Are Associated with Peptide-Binding Repertoires of Different Size, Affinity, and Immunogenicity

(2013) S. Paul et al.   JOURNAL OF IMMUNOLOGY

The Effect of Proteasome Inhibition on the Generation of the Human Leukocyte Antigen (HLA) Peptidome

(2013) Elena Milner et al.   MOLECULAR & CELLULAR PROTEOMICS

Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy

(2012) Valérie Dutoit et al.   BRAIN

The cancer antigenome

(2012) Bianca Heemskerk et al.   EMBO JOURNAL

Natural HLA class I ligands from glioblastoma: extending the options for immunotherapy

(2012) Marian Christoph Neidert et al.   JOURNAL OF NEURO-ONCOLOGY

Origin and plasticity of MHC I-associated self peptides

(2011) Danielle de Verteuil et al.   AUTOIMMUNITY REVIEWS

Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain

(2011) Sagar Agarwal et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

The Human Immunopeptidome Project, a Suggestion for yet another Postgenome Next Big Thing

(2011) Arie Admon et al.   MOLECULAR & CELLULAR PROTEOMICS

Identification and characterization of human leukocyte antigen class I ligands in renal cell carcinoma cells

(2011) Barbara Seliger et al.   PROTEOMICS

Direct quantitation of MHC-bound peptide epitopes by selected reaction monitoring

(2011) Chor Teck Tan et al.   PROTEOMICS

Phase I Trial of a Personalized Peptide Vaccine for Patients Positive for Human Leukocyte Antigen–A24 With Recurrent or Progressive Glioblastoma Multiforme

(2010) Mizuhiko Terasaki et al.   JOURNAL OF CLINICAL ONCOLOGY

Soluble plasma HLA peptidome as a potential source for cancer biomarkers

(2010) M. Bassani-Sternberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

(2009) Chunlei Wu et al.   GENOME BIOLOGY

HLA class I supertypes: a revised and updated classification

(2008) John Sidney et al.   BMC IMMUNOLOGY

The cancer biomarker problem

(2008) Charles L. Sawyers   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens

(2008) L. G. Almeida et al.   NUCLEIC ACIDS RESEARCH

Tumor escape mechanisms: potential role of soluble HLA antigens and NK cells activating ligands

(2008) M. Campoli et al.   TISSUE ANTIGENS