Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice

Insulin resistance and hippocampal dysfunction: Disentangling peripheral and brain causes from consequences

(2019) Claudia A. Grillo et al.   EXPERIMENTAL NEUROLOGY

The BET/BRD inhibitor JQ1 attenuates diabetes-induced cognitive impairment in rats by targeting Nox4-Nrf2 redox imbalance

(2018) Ershun Liang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-214-3p Targets β-Catenin to Regulate Depressive-like Behaviors Induced by Chronic Social Defeat Stress in Mice

(2018) Zhi-Fang Deng et al.   CEREBRAL CORTEX

Isoquercetin attenuates oxidative stress and neuronal apoptosis after ischemia/reperfusion injury via Nrf2-mediated inhibition of the NOX4/ROS/NF-κB pathway

(2018) Yunyi Dai et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The antidepressant effects of rosiglitazone on rats with depression induced by neuropathic pain

(2018) Jian Zong et al.   LIFE SCIENCES

Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between Obesity and Inflammation—Driven Liver and Colorectal Cancers

(2018) Lara Kern et al.   Cancers

Inflammatory mechanisms linking obesity and metabolic disease

(2017) Alan R. Saltiel et al.   JOURNAL OF CLINICAL INVESTIGATION

Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome

(2017) Pei Jiang et al.   Journal of Neuroinflammation

NADPH oxidase in brain injury and neurodegenerative disorders

(2017) Merry W. Ma et al.   Molecular Neurodegeneration

Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis

(2017) Zhan Zhao et al.   Frontiers in Molecular Neuroscience

Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function

(2016) Andreas Daiber et al.   BRITISH JOURNAL OF PHARMACOLOGY

Obesity and Cardiovascular Disease: a Risk Factor or a Risk Marker?

(2016) Taher Mandviwala et al.   Current Atherosclerosis Reports

FKBP5/FKBP51 enhances autophagy to synergize with antidepressant action

(2015) Nils C Gassen et al.   Autophagy

ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms

(2015) Lulu Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Is there a “metabolic-mood syndrome”? A review of the relationship between obesity and mood disorders

(2015) Rodrigo B. Mansur et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Molecular network of neuronal autophagy in the pathophysiology and treatment of depression

(2015) Jack Jia et al.   Neuroscience Bulletin

A review on the effects of Allium sativum (Garlic) in metabolic syndrome

(2015) A. Hosseini et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases

(2014) Li Gan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Novel Therapeutic Targets in Depression and Anxiety: Antioxidants as a Candidate Treatment

(2014) Ying Xu et al.   Current Neuropharmacology

Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults

(2014) Krishnan Bhaskaran et al.   LANCET

Mitochondrial dysfunction and oxidative damage in the brain of diet-induced obese rats but not in diet-resistant rats

(2014) Weiwei Ma et al.   LIFE SCIENCES

Neuroprotective effect of allicin against traumatic brain injury via Akt/endothelial nitric oxide synthase pathway-mediated anti-inflammatory and anti-oxidative activities

(2014) Wei Chen et al.   NEUROCHEMISTRY INTERNATIONAL

Molecular Mechanisms of the Crosstalk Between Mitochondria and NADPH Oxidase Through Reactive Oxygen Species—Studies in White Blood Cells and in Animal Models

(2013) Swenja Kröller-Schön et al.   ANTIOXIDANTS & REDOX SIGNALING

A Systematic Review and Meta-analysis of the Association Between Depression and Insulin Resistance

(2013) C. Kan et al.   DIABETES CARE

Pentamethylquercetin ameliorates fibrosis in diabetic Goto-Kakizaki rat kidneys and mesangial cells with suppression of TGF-β/Smads signaling

(2013) Xin Xin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Beneficial effects ofAllium sativumL. stem extract on lipid metabolism and antioxidant status in obese mice fed a high-fat diet

(2013) Inhye Kim et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Mitochondrial Dysfunction: A Basic Mechanism in Inflammation-Related Non-Communicable Diseases and Therapeutic Opportunities

(2013) Anna Hernández-Aguilera et al.   MEDIATORS OF INFLAMMATION

Increased oxidative stress in obesity: Implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer

(2013) Morihiro Matsuda et al.   Obesity Research & Clinical Practice

Adipokines Mediate Inflammation and Insulin Resistance

(2013) Hyokjoon Kwon et al.   Frontiers in Endocrinology

Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases

(2012) Tomohiro Nakamura et al.   EXPERIMENTAL NEUROLOGY

Obesity increases cerebrocortical reactive oxygen species and impairs brainfunction

(2012) Linnea R. Freeman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Obesity Comorbidity in Unipolar Major Depressive Disorder

(2012) Robert D. Levitan et al.   JOURNAL OF CLINICAL PSYCHIATRY

NADPH Oxidase Mediates Depressive Behavior Induced by Chronic Stress in Mice

(2012) J.-S. Seo et al.   JOURNAL OF NEUROSCIENCE

Oxidative stress and inflammation interactions in human obesity

(2012) Isabel Bondia-Pons et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Allicin ameliorates cognitive deficits ageing-induced learning and memory deficits through enhancing of Nrf2 antioxidant signaling pathways

(2012) Xian-Hui Li et al.   NEUROSCIENCE LETTERS

NADPH oxidases: novel therapeutic targets for neurodegenerative diseases

(2012) Hui-Ming Gao et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Impaired CNS Leptin Action Is Implicated in Depression Associated with Obesity

(2011) Nobuko Yamada et al.   ENDOCRINOLOGY

PPARγ Agonist Improves Neuronal Insulin Receptor Function in Hippocampus and Brain Mitochondria Function in Rats with Insulin Resistance Induced by Long Term High-Fat Diets

(2011) Noppamas Pipatpiboon et al.   ENDOCRINOLOGY

Inflammation, Oxidative Stress, and Obesity

(2011) Alba Fernández-Sánchez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: New pathways that underpin the inflammatory and neuroprogressive pathophysiology

(2011) Michael Maes et al.   JOURNAL OF AFFECTIVE DISORDERS

Metabolic Depression

(2011) Nicole Vogelzangs et al.   JOURNAL OF CLINICAL PSYCHIATRY

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

(2010) Michael Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Autophagy is upregulated in rats with status epilepticus and partly inhibited by Vitamin E

(2009) Lili Cao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Depression and anxiety among US adults: associations with body mass index

(2009) G Zhao et al.   INTERNATIONAL JOURNAL OF OBESITY

Adiponectin Levels and Risk of Type 2 Diabetes

(2009) Shanshan Li et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Attenuation of streptozotocin-induced oxidative stress in hepatic and intestinal tissues of wistar rat by methanolic-garlic extract

(2008) V. Rajani Kanth et al.   ACTA DIABETOLOGICA

Increased oxidative stress in submitochondrial particles into the brain of rats submitted to the chronic mild stress paradigm

(2008) Giancarlo Lucca et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Modulation ofin vivooxidative status by exogenous corticosterone and restraint stress in rats

(2008) Ayesha Zafir et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS