Article
Urology & Nephrology
Kate Lyden, Robert Boucher, Guo Wei, Na Zhou, Jesse Christensen, Glenn M. Chertow, Tom Greene, Srinivasan Beddhu
Summary: The study tested the feasibility of reducing sedentary behavior in patients with chronic kidney disease, showing that intervention can reduce sedentary time and increase walking time effectively in the short term, but the effects diminished over time.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Urology & Nephrology
Guillermo Navarro Blackaller, Jonathan S. Chavez-Iniguez, Elsa Edith Carreon-Bautista, Francisco Javier Gonzalez-Torres, Miroslava Villareal-Contreras, Jose Roberto Barrientos Avalos, Pablo Maggiani Aguilera, Francisco Romo Rosales, Torres Mayorga Jose Antonio, Juan Alberto Gomez Fregoso, Jorge Isaac Michel Gonzalez, Guillermo Garcia-Garcia
Summary: Thyroid hormones can affect kidney function. The study aimed to evaluate the effects of LVX on proteinuria and eGFR in patients with CKD. LVX significantly reduced proteinuria and improved eGFR in the study.
KIDNEY INTERNATIONAL REPORTS
(2021)
Article
Urology & Nephrology
Li Li, Xin Zheng, Jin Deng, Junlin Zhou, Jihong Ou, Tao Hong
Summary: This meta-analysis suggests that ferric citrate, an iron-based phosphate binder, is an effective and safe treatment option for CKD patients with hyperphosphatemia and anemia. It may also be a cost-effective alternative.
Article
Urology & Nephrology
Jessica Kendrick, Zhiying You, Emily Andrews, Heather Farmer-Bailey, Kerrie Moreau, Michel Chonchol, Cortney Steele, Wei Wang, Kristen L. Nowak, Nayana Patel
Summary: This study showed that increasing serum bicarbonate levels does not improve vascular function in patients with CKD and normal bicarbonate levels.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Nutrition & Dietetics
Steven Pratscher, Angela M. Mickle, John G. Marks, Harold Rocha, Felix Bartsch, Jeffrey Schmidt, Lazaro Tejera, Steven Garcia, Carlo Custodero, Federlin Jean, Cynthia Garvan, Alisa J. Johnson, Ralisa Pop, Anthony Greene, Adam J. Woods, Roland Staud, Roger B. Fillingim, Andreas Keil, Kimberly T. Sibille
Summary: Chronic pain can impact mental and physical health, but interventions such as intermittent fasting and glucose administration can improve learning and memory abilities and increase neuroplasticity in older adults. This pilot study tested the feasibility and acceptability of combining intermittent fasting and glucose administration with a recognized pain treatment activity, showing that it was successful and providing evidence to move forward with a larger clinical trial.
Review
Urology & Nephrology
Jonathan W. Bazeley, Jay B. Wish
Summary: This article discusses the diagnostic criteria and treatment principles for iron deficiency in individuals with chronic kidney disease, as well as the advantages and disadvantages of oral and intravenous iron agents. The potential risk of 6H syndrome associated with intravenous iron therapy is emphasized.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2022)
Article
Urology & Nephrology
Iain Bressendorff, Ditte Hansen, Morten Schou, Charlotte Kragelund, My Svensson, Bahram Hashemi, Tilde Kristensen, Marie Houmaa Vrist, Rikke Borg, Birgitte Tougaard, Kristine Borg, Henrik Oder Hjortkjaer, Cathrine Helgestad Kristiansen, Nicholas Carlson, Mohammad Nasiri, Haseem Ashraf, Andreas Pasch, Lisbet Brandi
Summary: This study aimed to investigate whether oral magnesium supplementation could slow the progression of vascular calcification in patients with CKD. However, the results showed that magnesium supplementation did not slow the progression of vascular calcification in CKD, despite an increase in plasma magnesium level.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Psychiatry
Harald Baekkelund, Pal Ulvenes, Suzette Boon-Langelaan, Espen Ajo Arnevik
Summary: This study is the first randomized controlled trial for the treatment of complex dissociative disorders. The results showed that stabilizing group treatment did not produce immediate significant effects, but the treatment was associated with improvements in psychological functioning.
Article
Oncology
Lauren P. Wallner, Paul Abrahamse, Joan G. Gargaro, Archana Radhakrishnan, Megan A. Mullins, Lawrence C. An, Jennifer J. Griggs, Anne F. Schott, John Z. Ayanian, Anne E. Sales, Steven Katz, Sarah T. Hawley
Summary: The multi-level intervention ConnectedCancerCare (CCC) showed promise in improving patient knowledge, patient-provider communication, and encouraging patients to engage with their primary care provider early in the survivorship period among women with early-stage breast cancer. Deploying CCC in medical oncology practices was feasible and intervention content was acceptable.
BREAST CANCER RESEARCH AND TREATMENT
(2021)
Article
Transplantation
Annabel Biruete, Corinne E. Metzger, Neal X. Chen, Elizabeth A. Swallow, Curtis Vrabec, Erica L. Clinkenbeard, Alexander J. Stacy, Shruthi Srinivasan, Kalisha O'Neill, Keith G. Avin, Matthew R. Allen, Sharon M. Moe
Summary: This study compared the effects of ferric citrate (FC) and intravenous iron sucrose in rats with moderate chronic kidney disease (CKD). The results showed that FC treatment improved phosphorus homeostasis, some iron-related parameters, and the production and cleavage of FGF23. However, neither iron treatment had a significant effect on cardiovascular calcification and bone.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Medicine, General & Internal
Ling-Yu Qi, Jing-Wen Yang, Shi-Yan Yan, Jian-Feng Tu, Yan-Fen She, Ying Li, Li-Li Chi, Bang-Qi Wu, Cun-Zhi Liu
Summary: Acupuncture is a promising therapy for irritable bowel syndrome (IBS), and this pilot study demonstrates clinically meaningful improvement in IBS symptoms with acupuncture treatment. However, there were no significant differences in efficacy among different acupuncture methods.
Article
Nutrition & Dietetics
Lara Caldiroli, Simone Vettoretti, Silvia Armelloni, Deborah Mattinzoli, Masami Ikehata, Paolo Molinari, Carlo Alfieri, Piergiorgio Messa, Giuseppe Castellano
Summary: This study compared the effects of low protein and normal protein diets on the nutritional status and metabolic complications related to the progression of kidney damage in older patients with advanced chronic kidney disease. The results showed that the low protein diet may have greater benefits on the progression of kidney disease and some of its metabolic complications.
FRONTIERS IN NUTRITION
(2022)
Article
Psychology, Multidisciplinary
Kenichi Asano, Masao Tsuchiya, Yoko Okamoto, Toshiyuki Ohtani, Toshihiko Sensui, Akihiro Masuyama, Ayako Isato, Masami Shoji, Tetsuya Shiraishi, Eiji Shimizu, Chris Irons, Paul Gilbert
Summary: The study shows that group compassion-focused therapy (CFT) has good feasibility for treatment-resistant depression (TRD) in Japanese clinical settings. It significantly reduces depressive symptoms and increases self-compassion.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Environmental Sciences
Mina Ghahrchi, Abbas Rezaee
Summary: The integrated electro-catalytic ozonation process using Fe-EDTA combined with electrocoagulation significantly enhances COD removal efficiency in landfill leachate, ultimately reducing sludge production.
Article
Urology & Nephrology
Susan P. Y. Wong, Taryn Oestreich, David K. Prince, J. Randall Curtis
Summary: This study assessed the feasibility and acceptability of a decision aid on conservative kidney management (CKM) among patients with advanced chronic kidney disease (CKD) and their family members. Results showed that the decision aid increased the discussion of CKM with healthcare providers for patients and their family members. This aid may serve as a useful adjunct to the currently available educational tools on treatments for advanced CKD.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2023)
Article
Urology & Nephrology
Alejandro Y. Meraz-Munoz, Nivethika Jeyakumar, Bin Luo, William Beaubien-Souligny, Rahul Chanchlani, Edward G. Clark, Ziv Harel, Abhijat Kitchlu, Javier A. Neyra, Michael Zappitelli, Glenn M. Chertow, Amit X. Garg, Ron Wald, Samuel A. Silver
Summary: Patients with a history of MI who survived AKI were less likely to receive prescriptions for cardiovascular drugs within 1 year of hospital discharge. This association was most pronounced in patients with stages 2 and 3 AKI.
KIDNEY INTERNATIONAL REPORTS
(2023)
Article
Endocrinology & Metabolism
Jelle M. Beernink, Frederik Persson, Niels Jongs, Gozewijn D. Laverman, Glenn M. Chertow, John J. V. McMurray, Anna Maria Langkilde, Ricardo Correa-Rotter, Peter Rossing, C. David Sjostrom, Robert D. Toto, David C. Wheeler, Hiddo J. L. Heerspink
Summary: This study aimed to determine whether the benefits of dapagliflozin varied by background glucose-lowering therapy (GLT) in patients with type 2 diabetes and chronic kidney disease (CKD). The results demonstrated consistent effects of dapagliflozin on both primary and secondary endpoints across different baseline GLT classes or combinations. Therefore, dapagliflozin has significant clinical implications in reducing kidney and cardiovascular events.
Article
Medicine, General & Internal
Marika M. Cusick, Rebecca L. Tisdale, Glenn M. Chertow, Douglas K. Owens, Jeremy D. Goldhaber-Fiebert
Summary: Adding SGLT2 inhibitors to CKD screening can be cost-effective, with a one-time screening at age 55 having an ICER of $86,300 per QALY gained, reducing the incidence of kidney failure. Screening every 10 years from age 35 to 75 costs less than $100,000 per QALY gained.
ANNALS OF INTERNAL MEDICINE
(2023)
Article
Oncology
Simon John Christoph Soerensen, Maria E. Montez-Rath, Iona Cheng, Scarlett Lin Gomez, Debora L. Oh, Christian Jackson, Jinhui Li, David Rehkopf, Glenn M. Chertow, Marvin E. Langston, Calyani Ganesan, Alan C. Pao, Benjamin I. Chung, John T. Leppert
Summary: This study evaluated the association between groundwater exposures and kidney cancer incidence and identified several groundwater constituents associated with kidney cancer. Public health efforts to reduce the burden of kidney cancer should consider groundwater constituents as environmental exposures that may be associated with the incidence of kidney cancer.
Article
Urology & Nephrology
Shuchi Anand, Maria Montez-Rath, Meri Varkila, Xue Yu, Martha Block, Stephanie Brillhart, Amanda Leppink, Patti Hunsader, Douglas K. Owens, Glenn M. Chertow, Julie Parsonnet, Geoffrey A. Block
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Urology & Nephrology
Calyani Ganesan, Malorie Holmes, Sai Liu, Maria Montez-Rath, Simon Conti, Timothy C. C. Chang, Colin R. Lenihan, Xingxing S. S. Cheng, Glenn M. Chertow, John T. Leppert, Alan C. C. Pao
Summary: Background: Kidney stone disease is common and can lead to complications in kidney transplant recipients. This study found that approximately 2% of kidney transplant recipients were diagnosed with a kidney stone in the first 3 years after transplantation. Risk factors for kidney stone events included a history of kidney stones and longer dialysis vintage.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Glenn M. Chertow, Ricardo Correa-Rotter, Priya Vart, Niels Jongs, John J. V. McMurray, Peter Rossing, Anna Maria Langkilde, C. David Sjostrom, Robert D. Toto, David C. Wheeler, Hiddo J. L. Heerspink
Summary: In the DAPA-CKD trial, dapagliflozin was found to reduce the risk of kidney and cardiovascular events in patients with chronic kidney disease and albuminuria. The treatment effect of dapagliflozin was consistent regardless of baseline cardiovascular medication use.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Review
Physiology
Fengyun Wang, Lixin Zhou, Amity Eliaz, Chang Hu, Xinhua Qiang, Li Ke, Glenn Chertow, Isaac Eliaz, Zhiyong Peng
Summary: Acute kidney injury (AKI) and chronic kidney disease (CKD) are associated with high morbidity and mortality. Galectin-3 (Gal3), a protein with proinflammatory and profibrotic properties, has been implicated in the development and progression of both AKI and CKD. Elevated Gal3 levels in the serum of AKI and CKD patients and its association with CKD progression have been observed. Gal3 is also associated with AKI incidence in critically ill patients, and blocking Gal3 has shown promising results in reducing AKI incidence and mortality in animal models.
FRONTIERS IN PHYSIOLOGY
(2023)
Letter
Medicine, General & Internal
Priya Vart, Niels Jongs, David C. Wheeler, Hiddo J. L. Heerspink, Anna Maria Langkilde, Glenn M. Chertow
Letter
Medicine, General & Internal
Vikram Fielding-Singh, Matthew W. Vanneman, Arden M. Morris, Glenn M. Chertow, Eugene Lin
Summary: This cohort study examines the relationship between patient characteristics and the time interval between hemodialysis and surgery in end-stage kidney disease patients.
Meeting Abstract
Transplantation
Hiddo Lambers Heerspink, David C. Wheeler, Niels Jong, Ricardo Correa-Rotter, Peter Rossing, Ronald Gansevoort, John Mcmurray, Anna Maria Langkilde, Robert Toto, Glenn Chertow
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Meeting Abstract
Transplantation
Bertrand Knebelmann, Kate Bramham, Kieran Mccafferty, Mohamad Zaidan, Pablo Antonio Urena Torres, Vincent Audard, Jean Jacques Boffa, Thomas Powell, Nauman Shahid, Diego Echeverri, Christopher Provenzano, John Bauman, Aurelia Zamauskaite, Irisz Delestre-Levai, Yuan Yang, Silva Krause, Anna Carolina Ferreira, Ogo Egbuna, Glenn Chertow
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Meeting Abstract
Transplantation
Margaret Yu, Priya Vart, Hiddo Lambers Heerspink, Niels Jong, Ricardo Correa-Rotter, John Mcmurray, Peter Rossing, Anna Maria Langkilde, Robert Toto, David C. Wheeler, Glenn Chertow
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Meeting Abstract
Transplantation
Zhiyan Zhang, Hiddo Lambers Ileerspink, Glenn Chertow, Ricardo Correa-Rotter, Antonio Gasparrini, Niels Jong, Anna Maria Langkilde, Malcolm Mistry, John Mcmurray, Peter Rossing, Robert Toto, Priya Vart, Dorothea Misch, David C. Wheeler, Ben Caplin
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Meeting Abstract
Medicine, Research & Experimental
Halimat Afolabi, Bing Zhang, Michelle O'Shaughnessy, Glenn Chertow, Richard Lafayette, Vivek Charu
LABORATORY INVESTIGATION
(2023)