期刊
JOURNAL OF EXPERIMENTAL MEDICINE
卷 216, 期 7, 页码 1471-1473出版社
ROCKEFELLER UNIV PRESS
DOI: 10.1084/jem.20190721
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Members of the MYC family of oncogenes are master regulators of mRNA translation. In this issue of JEM, Singh et al. (https://doi.org/10.1084/jem.20181726) demonstrate that c-Myc governs protein synthesis in lymphoma cells by interfering with SRSF1- and RBM42-mediated suppression of mRNA translation and by altering selection of translation initiation sites.
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