Review
Environmental Sciences
Juan P. Munoz, Eduardo Silva-Pavez, Diego Carrillo-Beltran, Gloria M. Calaf
Summary: This study aimed to review glyphosate occurrence and exposure since 2015, considering studies associated with environmental or occupational exposure and the epidemiological assessment of cancer risk. The results showed that herbicide residues were detectable in all spheres of the earth and studies on the population showed an increase in glyphosate concentration in biofluids. However, the reviewed epidemiological studies provided limited evidence for the carcinogenicity of glyphosate, which was consistent with the International Agency for Research on Cancer classification as a probable carcinogen.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Monica Martinez-Haro, Jose Manuel Chinchilla, Pablo R. Camarero, Jose Alberto Vinuelas, Maria Jesus Crespo, Rafael Mateo
Summary: A procedure based on liquid chromatography-high resolution tandem mass spectrometry was developed for the determination of glyphosate in wildlife gastric content. The method was validated and shown to be accurate and precise. The results revealed a higher prevalence of glyphosate in animals from pesticide-treated areas compared to animals from pesticide-free areas.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Agronomy
Ricardo Alcantara-de la Cruz, Hugo E. Cruz-Hipolito, Jose Alfredo Dominguez-Valenzuela, Rafael De Prado
Summary: The Mexican government has decreed a ban on glyphosate starting in 2024, but there are no safer alternatives in the current agricultural setting, leading to potential impacts such as decreased crop yields and increased food prices.
PEST MANAGEMENT SCIENCE
(2021)
Article
Environmental Sciences
Deeksha Rawat, Aarti Bains, Prince Chawla, Ravinder Kaushik, Rahul Yadav, Anil Kumar, Kandi Sridhar, Minaxi Sharma
Summary: With the decreasing farming lands due to the growing human population, agricultural scientists are developing new strategies for effective crop management. However, the excessive use of herbicides to deal with the loss caused by small plants and herbs has raised concerns about its environmental and health effects. Glyphosate, extensively used for the past 40 years with assumed negligible effects, has now been classified as a carcinogenic toxic component by the World Health Organization and banned in 2017. This review discusses the importance of glyphosate monitoring in the food matrix, its environmental and health effects, and advanced analytical techniques for its detection.
Article
Environmental Sciences
Eva Caroline Nunes Rezende, Fernanda Melo Carneiro, Jonathan Ballico de Moraes, Isabela Jube Wastowski
Summary: Glyphosate, as one of the most successful ingredients of agrochemical companies, has been shown to have significant harmful effects on both human and environmental health. Studies indicate that even herbicide concentrations slightly below official safety limits can induce toxic effects. Countries heavily investing in large-scale agriculture are the main contributors to research on glyphosate toxicity, yet concise data supporting the adverse effects of these pesticides on health are lacking, highlighting the need for sustainable global alternatives.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Environmental Sciences
Marie-Helene Bacon, Louise Vandelac, Marc-Andre Gagnon, Lise Parent
Summary: Despite the global discourse on reducing pesticide use, the agricultural sector has witnessed an exponential increase in pesticide usage over the past three decades. Glyphosate-Based Herbicides (GBHs) are the most commonly used pesticides worldwide, including in Canada, where almost 470 million kilograms of glyphosate were sold between 2007 and 2018. In 2017, GBHs accounted for 58% of agricultural pesticide use in Canada. This article examines how the Canadian regulation and scientific assessment of pesticides, particularly GBHs, lag behind other countries due to scientific and regulatory captures by the pesticide industry, compromising public health and environmental protection.
Article
Environmental Sciences
Lisa Buchenauer, Kristin M. Junge, Sven-Bastiaan Haange, Jan C. Simon, Martin von Bergen, Anna-Lena Hoh, Gabriela Aust, Ana C. Zenclussen, Gabriele I. Stangl, Tobias Polte
Summary: Exposure to low-dose glyphosate in mothers has an immunosuppressive effect on their female offspring, which is not observed in the second generation. The altered microbiota composition might mediate this immune response modulation.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biology
Pere Puigbo, Lyydia Leino, Miia J. Rainio, Kari Saikkonen, Irma Saloniemi, Marjo Helander
Summary: Glyphosate, the most widely used agrochemical, was previously considered safe for human microbiota due to the absence of the target enzyme, but recent studies have shown potential risks to human microbiome. Further research is needed to determine the effects of glyphosate on healthy human microbiota.
Article
Public, Environmental & Occupational Health
Karoly Nagy, Roba Argaw Tessema, Istvan Szasz, Tamara Smeirat, Alaa Al Rajo, Balazs Adam
Summary: The study compared the cytogenetic effect of the active ingredient glyphosate and three marketed GBHs on isolated human white blood cells, indicating that the co-formulants in herbicide formulations may interact with the active ingredient, increasing toxicity.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Ecology
Isabela Sousa Prado, Agda Alves da Rocha, Lais Alves Silva, Vinicius Cunha Gonzalez
Summary: Declining bee populations due to pesticides, especially glyphosate-based formulations, negatively impact pollination services and bee behavior. This study found that glyphosate-based formulations are highly toxic to Tetragonisca angustula bees, causing death, motor changes, excessive self-cleaning, and disorientation. Understanding the toxicity and sublethal effects of pesticides on bees is crucial for mitigating their harmful impacts and preserving bee populations and ecological biodiversity.
Review
Food Science & Technology
Fernando Alvarez, Domenica European Food Safety Authority EFSA, Maria Arena, Domenica Auteri, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Federica Crivellente, Mark Egsmose, Gabriella Fait, Franco Ferilli, Varvara Gouliarmou, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Alberto Linguadoca, Christopher Lythgo, Iris Mangas, Laura Padovani, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnes Rortais, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, Laura Villamar-Bouza
Summary: The EFSA reports the conclusions of the peer review carried out by the AGG on the initial risk assessments of the pesticide glyphosate. The review evaluated various uses of glyphosate as a herbicide proposed by the applicants, including pre-sowing, pre-planting, pre-emergence, and post-harvest uses in vegetables and sugar beet, as well as post-emergence use in orchards, vineyards, row vegetables, and railway tracks. Missing information required by the regulatory framework is identified, and concerns are reported.
Article
Biodiversity Conservation
Christopher J. E. Haggerty, Neal T. Halstead, David J. Civitello, Jason R. Rohr
Summary: Certain insecticides were found to increase snail populations that transmit schistosomiasis, while others may improve food production without increasing the risk of the disease. Fertilizers were also shown to have strong positive effects on snail populations, highlighting the need to identify low-risk insecticides to reduce crop pests without increasing schistosomiasis risk.
JOURNAL OF APPLIED ECOLOGY
(2022)
Article
Environmental Sciences
Gulsah Congur
Summary: Glyphosate is commonly used herbicide, but its carcinogenic and genotoxic potential has been extensively investigated worldwide in recent years. The study developed an electrochemical biosensor platform to investigate the interaction between glyphosate and DNA, as well as the synergistic genotoxic effect of glyphosate and 2,4-dichlorophenoxyacetic acid on DNA. Results showed that the herbicide mixture exhibited more genotoxic effect.
ENVIRONMENTAL POLLUTION
(2021)
Article
Ecology
Livia Maria Negrini Ferreira, Michael Hrncir, Danilo Vieira de Almeida, Rodrigo Cupertino Bernardes, Maria Augusta Pereira Lima
Summary: The study showed that realistic concentrations of acephate-based insecticides are harmful to the survival and mobility of stingless bees, while glyphosate-based herbicides are safe for forager bees under realistic concentrations.
Article
Agronomy
Arthur Arrobas Martins Barroso, Thomas Bruno Michelon, Pedro Luis da Costa Aguiar Alves, Heping Han, Qin Yu, Stephen B. Powles, Martin M. Vila-Aiub
Summary: Goosegrass (Eleusine indica) with double Thr-102-Ile + Pro-106-Ser (TIPS) EPSPS mutations shows high resistance to glyphosate, but also incurs a substantial fitness cost. Soybean competition further increases this fitness cost, resulting in 95%, 95%, and 96% reductions in vegetative growth, seed mass, and seed number, respectively. Glyphosate treatment enhances growth in TIPS plants compared to untreated plants. Conversely, moderate glyphosate resistance mutation P106S shows decreased survival rate, vegetative growth, aboveground biomass (34%), seed mass (48%), and number (52%) when treated with glyphosate alone. However, under the combined effects of soybean competition and field-recommended glyphosate dose, both P106S and TIPS plants have significantly limited vegetative growth, aboveground biomass, seed mass, and number (≤99%).
PEST MANAGEMENT SCIENCE
(2022)