Effects of partial vascular occlusion on irisin responses to loaded muscle contractions

The purpose of the study was to determine the effects of partial vascular occlusion on irisin responses. Eight males completed trials of light (30% 1-repetition maximum (1RM)) resistance exercise (single biceps curls and calf presses) with partial vascular occlusion (LRO), moderate resistance (70% 1RM) with no occlusion (MR), and occlusion only (00). Blood was collected before, after, and 15 min after exercise. Changes in circulating irisin were more affected during LRO than MR and 00 trials.