microRNA-141 is associated with hepatic steatosis by downregulating the sirtuin1/AMP-activated protein kinase pathway in hepatocytes

miR-141-3p commonly regulates human UGT1A isoforms via different mechanisms

(2018) Naoyuki Tatsumi et al.   Drug Metabolism and Pharmacokinetics

Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance

(2018) Zahra Arab Sadeghabadi et al.   Obesity Research & Clinical Practice

AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development

(2018) Nadia Boudaba et al.   EBioMedicine

MicroRNA-138 Aggravates Inflammatory Responses of Macrophages by Targeting SIRT1 and Regulating the NF-κB and AKT Pathways

(2018) Xiao-Zhi Bai et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Obesity-induced upregulation of miR-361-5p promotes hepatosteatosis through targeting Sirt1

(2018) Zhijian Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Serum microRNA-211 as a biomarker for diabetic retinopathy via modulating Sirtuin 1

(2018) He-Nan Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments

(2017) Hironori Kitade et al.   Nutrients

The association between obesity related adipokines and risk of breast cancer: a meta-analysis

(2017) Yu Gui et al.   Oncotarget

Identification of miR-31-5p, miR-141-3p, miR-200c-3p, and GLT1 as human liver aging markers sensitive to donor-recipient age-mismatch in transplants

(2016) Miriam Capri et al.   AGING CELL

Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid-fed mouse model of cholestasis

(2016) Supriya R. Kulkarni et al.   HEPATOLOGY

SIRT1 and insulin resistance

(2016) Yue Cao et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids

(2016) Takamasa Tobita et al.   PLoS One

Sirtuins and nonalcoholic fatty liver disease

(2016) Fatiha Nassir et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Altered microRNA-9 Expression Level is Directly Correlated with Pathogenesis of Nonalcoholic Fatty Liver Disease by Targeting Onecut2 and SIRT1

(2016) Ran Ao et al.   MEDICAL SCIENCE MONITOR

Differential expression of serum microRNAs in cirrhosis that evolve into hepatocellular carcinoma related to hepatitis B virus

(2015) YOUWEN TAN et al.   ONCOLOGY REPORTS

Serum MicroRNAs as Potential Biomarkers of Primary Biliary Cirrhosis

(2014) Youwen Tan et al.   PLoS One

Dual Role of MicroRNAs in NAFLD

(2013) Sara Ceccarelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential

(2013) Munehiro Kitada et al.   Diabetes & Metabolism Journal

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Uric Acid Stimulates Fructokinase and Accelerates Fructose Metabolism in the Development of Fatty Liver

(2012) Miguel A. Lanaspa et al.   PLoS One

MiR-34, SIRT1, and p53: The feedback loop

(2011) Munekazu Yamakuchi et al.   CELL CYCLE

Current therapeutic strategies in non-alcoholic fatty liver disease

(2011) J. K. Dowman et al.   DIABETES OBESITY & METABOLISM

MicroRNAs and liver disease

(2011) Thomas A. Kerr et al.   Translational Research

microRNAs: Fad or future of liver disease

(2011) Ashley M Lakner   WORLD JOURNAL OF GASTROENTEROLOGY

AMPK and SIRT1: a long-standing partnership?

(2010) Neil B. Ruderman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

SIRT1 regulation of apoptosis of human chondrocytes

(2009) Koji Takayama et al.   ARTHRITIS AND RHEUMATISM

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1

(2009) S. B. Rajamohan et al.   MOLECULAR AND CELLULAR BIOLOGY

A three-dimensional view of the molecular machinery of RNA interference

(2009) Martin Jinek et al.   NATURE

SIRT1 Regulates Hepatocyte Lipid Metabolism through Activating AMP-activated Protein Kinase

(2008) Xiuyun Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY