Article
Chemistry, Applied
Syrine Dimassi, Nicolas Tabary, Feng Chai, Cedric Zobrist, Jean-Christophe Hornez, Frederic Cazaux, Nicolas Blanchemain, Bernard Martel
Summary: This study investigates the influence of treatment time of electrospun chitosan nanofibers in dopamine bath on polydopamine coating and biomimetic deposition of hydroxyapatite. The scaffolds showed promising cytocompatibility and induced biomineralization in vitro, making them potential candidates for bone regeneration applications. Characterization by FTIR, SEM, XRD, and SEM-EDS confirmed the formation of apatitic phase particles on the surface of the scaffolds.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Applied
Bikendra Maharjan, Jeesoo Park, Vignesh Krishnamoorthi Kaliannagounder, Ganesh Prasad Awasthi, Mahesh Kumar Joshi, Chan Hee Park, Cheol Sang Kim
Summary: This study addressed the insufficient mechanical strength of natural hydrogel scaffolds in bone tissue engineering by incorporating regenerated cellulose nanofibers into chitosan hydrogel. The resulting rCL/CS composite scaffold showed improved compressive strength, biomineralization, and pre-osteoblast cell viability. The enhanced osteogenic differentiation ability of rCL/CS composite scaffold suggests its promise as a three-dimensional bio-scaffold for bone tissue engineering.
CARBOHYDRATE POLYMERS
(2021)
Article
Biotechnology & Applied Microbiology
Elisa Roldan, Neil D. Reeves, Glen Cooper, Kirstie Andrews
Summary: This study evaluated the suitability of gelatin as the sole material to manufacture tissue engineering scaffolds. The gelatin-based electrospun scaffolds exhibited comparable mechanical properties to various human tissues, suggesting their potential application in tissue engineering.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Sneh Gautam, Shiv Dutt Purohit, Hemant Singh, Amit Kumar Dinda, Pravin D. Potdar, Chhavi Sharma, Chia -Fu Chou, Narayan Chandra Mishra
Summary: Bone tissue engineering has received attention for the treatment of bone injury. A tri-polymer scaffold (PCL-gelatin-chitosan) was fabricated through electrospinning and treated with nanohydroxyapatite. The modified scaffold showed a uniform distribution of nanohydroxyapatite particles on the surface of fibers.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Polymer Science
Zahra Moazzami Goudarzi, Tayebeh Behzad, Laleh Ghasemi-Mobarakeh, Mahshid Kharaziha
Summary: The study demonstrated that the addition of ACNF significantly improved the tensile strength of PCL/Gel scaffold, while reducing the degradation rate. Incorporation of ACNF showed no cytotoxic effects and promoted cell proliferation.
Review
Chemistry, Physical
Zahra Ebrahimvand Dibazar, Lei Nie, Mehdi Azizi, Houra Nekounam, Masoud Hamidi, Amin Shavandi, Zhila Izadi, Cedric Delattre
Summary: Bone tissue engineering combines biomaterials, cells, and bioactive agents to provide advanced treatment options. Scaffolds play a central role, and precise design and fabrication of structures that closely resemble bone tissue have shown promising results. The use of nanotechnology and nanomaterials in scaffolds allows for tailored physicochemical properties and improved interactions with cells and surrounding tissues. Polymeric and carbon nanofibers have attracted attention due to their similarity to bone extracellular matrix and high surface-to-volume ratio. Mineralized nanofibers have shown potential in enhancing bone healing in tissue engineering applications.
Article
Biotechnology & Applied Microbiology
Xiaoyu Wu, Su Ni, Ting Dai, Jingyan Li, Fang Shao, Chun Liu, Jiafeng Wang, Shijie Fan, Yadong Tan, Linxiang Zhang, Qiting Jiang, Hongbin Zhao
Summary: Researchers developed a PCL/Gelatin composite electrospun membrane with bubble-shaped nanofibrous structures, which improved biomineralization ability by increasing surface roughness and promoting mineralization. The membrane exhibited excellent cell compatibility and adhesion, and it effectively promoted vascularization and bone regeneration. The sustained-release of tetramethylpyrazine showed excellent drug release efficiency.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Polymer Science
Kristina Peranidze, Tatiana V. Safronova, Nataliya R. Kildeeva
Summary: Currently, the field of tissue engineering is focused on developing polymer-based materials with suitable microenvironments for cell attachment, differentiation, and proliferation. The biomimicking approach aims to create biocompatible and bioactive materials that mimic the structural features of the natural extracellular matrix. This study discusses promising fibrous materials for bone tissue regeneration obtained through electrospinning techniques, including natural and synthetic polymers combined with bioactive inorganic materials.
Article
Materials Science, Composites
Elham Sadeghi, Seyed Mojtaba Zebarjad, Farzaneh Khademi, Elham Bagherzadeh
Summary: In this study, PCL/Ge/HA core-shell nanocomposites were produced using coaxial electrospinning method. The resulting nanofibrous scaffolds showed good mechanical properties and biological activity, making them promising candidates for bone scaffolds.
POLYMER COMPOSITES
(2022)
Article
Materials Science, Multidisciplinary
Yasuhiro Ikegami, Muhammad Shafiq, Shinichi Aishima, Hiroyuki Ijima
Summary: Injuries to the nervous system have significant impact worldwide. Artificial nerve guidance conduits (NGCs) provide a promising solution for nerve reconstruction but need to replicate the in vivo microenvironment. This study developed heparin/growth factors (GFs)-immobilized artificial NGCs, which showed successful retention and bioactivity of nerve growth factor (NGF). The NGCs demonstrated good stability and biocompatibility in vivo, suggesting their potential in nerve regeneration and tissue engineering.
ADVANCED FIBER MATERIALS
(2023)
Article
Chemistry, Applied
Tanmay Bharadwaj, Shreya Chrungoo, Devendra Verma
Summary: Chitosan-based thermosensitive bioink has great potential for bone tissue engineering due to its excellent biocompatibility and gelation at physiological temperature without the need for crosslinkers. However, it has limitations in terms of low mechanical strength, poor printability, and low post-printing cell viability. This study incorporated self-assembled nanofibrous aggregates and nanohydroxyapatite into chitosan-based bioinks to improve their printability, mechanical properties, and cell viability. The optimized nanocomposite bioink showed good printability, high cell viability, low water uptake, and degradation in the presence of lysozyme. The bioink also exhibited a suitable elastic modulus and enhanced cellular activity in osteogenic media.
CARBOHYDRATE POLYMERS
(2024)
Article
Biochemistry & Molecular Biology
Soroush Ahmadi, Ahmad Hivechi, S. Hajir Bahrami, Peiman B. Milan, Seyedeh Sara Ashraf
Summary: This study developed chitosan/gelatin nanofiber membranes with sustained release capacity to prevent infection by delivering cinnamon extract (CE) in the implanted site. The incorporation of CE enhanced the properties of the nanofibers, including degradation behavior, antibacterial activity, and biocompatibility. The extract release profile showed a burst release in the first 6 hours, followed by a controlled release in the next 138 hours.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Sakchi Bhushan, Sandhya Singh, Tushar Kanti Maiti, Ankita Das, Ananya Barui, Leena R. Chaudhari, Meghnad G. Joshi, Dharm Dutt
Summary: Cell-free and cell-loaded constructs are used to repair critical-sized bone defects, with interest in enhancing three-dimensional scaffolds with free radical scavenging materials. In this study, CG-CNPs nanocomposite scaffolds with improved physico-chemical, mechanical, and biological properties were fabricated using freeze-drying. These scaffolds showed cyto-friendly behavior, antimicrobial activity, and demonstrated the best characteristics in terms of porosity, weight loss, compressive modulus, and Ca/P ratio. Therefore, the CG-CNP2 scaffolds are highly biocompatible and suitable for bone defect repair.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Multidisciplinary Sciences
Hesham R. El-Seedi, Noha S. Said, Nermeen Yosri, Hamada B. Hawash, Dina M. El-Sherif, Mohamed Abouzid, Mohamed M. Abdel-Daim, Mohammed Yaseen, Hany Omar, Qiyang Shou, Nour F. Attia, Xiaobo Zou, Zhiming Guo, Shaden A. M. Khalifa
Summary: The use of gelatin and gelatin-blend polymers for the synthesis of electrospun nanofibers has brought about a revolution in the biomedical field. Gelatin, despite variations in processing technology, is a versatile biopolymer. Electrospinning is an efficient and cost-effective technique for manufacturing gelatin electrospun nanofibers (GNFs), which have high porosity, large surface area, and biocompatibility. However, some limitations, such as rapid degradation and poor mechanical strength, can be overcome through cross-linking, leading to improved biological properties and various biomedical applications of GNFs.
Review
Biochemistry & Molecular Biology
Sakshi Priya, Unnati Batra, B. N. Samshritha, Sudhanshu Sharma, Akash Chaurasiya, Gautam Singhvi
Summary: Nanofibers are fibrous nanocarriers that can be synthesized from various materials, including natural polymers. Natural polysaccharides-based nanofibers have gained attention in pharmaceutical and biomedical applications due to their biocompatibility, biodegradability, non-toxicity, and economic advantages. However, there is a lack of research on the scale-up and advanced therapeutic delivery of nanofibers.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Narayanan Akshaya, Prakash Prasith, Balakrishnan Abinaya, Badrinath Ashwin, S. Chandran, Nagarajan Selvamurugan
Summary: The study confirmed that valproic acid (VA) has osteoinductive properties at both the cellular and molecular levels, promoting osteoblast differentiation and mineralization in mouse mesenchymal stem cells (mMSCs) through activation of key signaling pathways. This suggests potential applications for VA in bone therapeutics.
CURRENT MOLECULAR PHARMACOLOGY
(2021)
Article
Engineering, Biomedical
K. Mohamed Abudhahir, R. Murugesan, R. Vijayashree, N. Selvamurugan, Tze-Wen Chung, A. Moorthi
Summary: This study focuses on the wound healing process and aims to develop new wound dressings to overcome the drawbacks of conventional ones. The synthesized Zn-Ws particles show potential for antimicrobial and wound healing applications in skin tissue engineering, indicating promising prospects for clinical use.
JOURNAL OF BIOMATERIALS APPLICATIONS
(2021)
Article
Engineering, Biomedical
Mohamed Abudhahir, Azeena Saleem, Pragyan Paramita, Sukumar Dinesh Kumar, Chung Tze-Wen, Nagarajan Selvamurugan, Ambigapathi Moorthi
Summary: The biocomposite scaffold synthesized in this study by combining PCL, Ws, and Cu exhibited micro-fibrous surface morphology and showed potential for promoting bone formation.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2021)
Article
Medicine, Research & Experimental
N. Akshaya, N. Srinaath, M. Rohini, R. Ilangovan, N. Selvamurugan
Summary: In this study, the authors investigated the role of PTH-responsive miR-290 in the regulation of Runx2-mediated MMP-13 expression in rat osteoblastic cells. The results suggested that miR-290 may serve as a molecular marker or target for bone and bone-related diseases.
CURRENT MOLECULAR MEDICINE
(2022)
Article
Materials Science, Biomaterials
Soubhagya Attayil Sukumaran, Balagangadharan Kalimuthu, Nagarajan Selvamurugan, Prabaharan Mani
Summary: The microporous films composed of chitosan, gelatin and magnesium oxide nanoparticles demonstrated improved swelling behavior, mechanical strength, antimicrobial activity, biocompatibility, bioactivity, and cell migration ability, making them a potential dermal substitute for wound healing applications.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2022)
Article
Biochemistry & Molecular Biology
R. Mohanapriya, R. L. Akshaya, N. Selvamurugan
Summary: Osteoblast differentiation is a crucial process in skeletal development and bone remodeling, and its regulation involves various non-coding RNAs. Circular RNAs and microRNAs can directly or indirectly regulate the expression of osteoblast marker genes and interact with mRNAs. Understanding these regulatory mechanisms can provide valuable insights for diagnosing and treating bone and bone-related disorders.
Article
Biochemistry & Molecular Biology
Kanagaraj Gomathi, Muthukumar Rohini, Nicola C. Partridge, Nagarajan Selvamurugan
Summary: This study demonstrated the transcriptional regulation of MMP13 by TGF-beta 1 via Runx2 acetylation in rat osteoblastic cells, contributing to the knowledge of events presiding bone metabolism.
BIOLOGICAL CHEMISTRY
(2022)
Review
Biochemical Research Methods
Dharmaraj Saleth Sidharthan, Ranganathan Abhinandan, Kalimuthu Balagangadharan, Nagarajan Selvamurugan
Summary: The dynamic biology of bone provides abundant biomolecular targets, where delivery of nucleic acids can enhance regeneration. Advances in nanomaterials offer effective transfection tools, while CRISPR and DNA nanostructures show great potential in regenerative medicine.
BIOTECHNOLOGY JOURNAL
(2022)
Article
Engineering, Biomedical
A. S. Soubhagya, K. Balagangadharan, N. Selvamurugan, D. Sathya Seeli, M. Prabaharan
Summary: A novel type of porous three-dimensional film CCMPBG was fabricated using the freeze-drying method, showing improved biocompatibility, antimicrobial activity and wound closure ability, making it an effective dressing material for wound therapy.
JOURNAL OF BIOMATERIALS APPLICATIONS
(2022)
Article
Cell Biology
R. Hari Krishnan, Lakshana Sadu, Udipt Ranjan Das, Sneha Satishkumar, S. Pranav Adithya, I Saranya, R. L. Akshaya, N. Selvamurugan
Summary: This review article introduces the function of p300 in osteoblast differentiation. As a factor with histone acetyltransferase activity, p300 plays an important role in regulating histones and transcription factors. The article also highlights the regulation of p300 at posttranscriptional and non-coding RNA levels, which may have an indirect influence on bone formation.
Review
Biotechnology & Applied Microbiology
Abinaya Shanmugavadivu, Kalimuthu Balagangadharan, Nagarajan Selvamurugan
Summary: Bone relies on the close interaction between blood vessels and bone cells for formation and healing. Angiogenesis is critical for bone regeneration as it delivers oxygen, nutrients, and growth factors. Flavonoids have shown potential in promoting bone regeneration due to their bioactivity, low cost, availability, and minimal toxicity. Further research is needed to investigate their delivery strategies and clinical efficacy.
BIOTECHNOLOGY AND BIOENGINEERING
(2022)
Review
Biochemistry & Molecular Biology
Lakshana Sadu, R. Hari Krishnan, R. L. Akshaya, Udipt Ranjan Das, Sneha Satishkumar, N. Selvamurugan
Summary: Exosomes play a crucial role in bone remodeling and breast cancer bone metastasis, and have the potential to serve as biomarkers or delivery vehicles for the diagnosis and treatment of breast cancer bone metastasis.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ganesh Harini, S. Shree Ganesh, Ramprasad Anushikaa, Ramanathan Bharathi, Sankaranarayanan Aravind, Kumari Vatsala, Abinaya Shanmugavadivu, Nagarajan Selvamurugan
Summary: This study evaluated the anticancer effect of veratric acid (VA) on highly invasive triple-negative breast cancer (TNBC), using polydopamine nanoparticles (nPDAs) as a drug carrier for sustained release. The pH-sensitive nano-formulations of VA-loaded nPDAs showed good colloidal stability and sustained release, targeting tumor cells. The VA-nPDAs exhibited higher antiproliferative effects and induced apoptosis in MDA-MB-231 cells compared to free VA, indicating the potential of VA as an anticancer agent.
CHEMISTRY & BIODIVERSITY
(2023)
Review
Materials Science, Multidisciplinary
Ganesh Harini, Ramanathan Bharathi, Aravind Sankaranarayanan, Abinaya Shanmugavadivu, Nagarajan Selvamurugan
Summary: In recent years, the use of nanomaterials in tissue engineering has increased significantly. Nanostructured scaffolds with cells provide a supportive environment similar to natural bone microarchitecture and regulate cell functions for tissue development. Chitosan, a promising biomaterial, has remarkable qualities but lacks mechanical strength. Combinations of chitosan with other biomaterials, such as bioceramics, can overcome this limitation. The review article discusses the use of bioinert, bioresorbable, and bioactive nanoceramics-reinforced chitosan scaffolds in bone tissue engineering and highlights their advantages and challenges in bone defect regeneration.
MATERIALS ADVANCES
(2023)
Review
Chemistry, Multidisciplinary
Aravind Sankaranarayanan, Anushikaa Ramprasad, S. Shree Ganesh, Harini Ganesh, Bharathi Ramanathan, Abinaya Shanmugavadivu, Nagarajan Selvamurugan
Summary: Nanogels are hydrogel nanoparticles with porous structure, combining the advantages of hydrogels and nanoparticles. They have attracted attention in bone tissue engineering for growth factor transport and cell adhesion. Nanogels can encapsulate various drugs, enhance their stability, and hinder enzymatic breakdown. They act as carriers for controlled release, mechanical support, and osteogenesis in bone tissue regeneration. This review highlights the potential of nanogel-based scaffolds in bone tissue engineering.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
