Article
Environmental Sciences
Jun Li, Liang Xu, Yihui Zhou, Ge Yin, Yan Wu, Guo-Li Yuan, Xinyu Du
Summary: This study investigated the role of waste disposal in the Tibetan plateau as a local source of short-chain chlorinated paraffins (SCCPs), finding a significant release of SCCPs from waste disposal and extra release of volatile SCCPs from open-burning dumpsites. Urbanization and badly-managed landfills have been contributing to the presence of contemporary POPs in the Tibetan Plateau.
Article
Environmental Sciences
Hongmei Hu, Jianli Qu, Meirong Zhao, Pengfei Wu, Wenbin Zhu, Yongdong Zhou, Hangbiao Jin
Summary: The study found that in the East China Sea, the concentrations of short chain chlorinated paraffins (SCCPs) in both seawater and marine organisms varied within a certain range, indicating potential trophic magnification of SCCPs in the marine food web. It was suggested that hydrophobicity is the major factor influencing the bioaccumulation of SCCPs.
MARINE POLLUTION BULLETIN
(2021)
Article
Environmental Sciences
Lixin Yang, Yinping Liu, Ze Cui, Yongmao Zhang, Jianbo Zhang, Kaoqi Lian
Summary: This study used a metabolomics approach to investigate the toxicity of SCCPs in rats, finding that high-dose SCCP exposure resulted in liver and kidney injury, affecting pathways related to energy metabolism, amino acid metabolism, glycerophospholipid metabolism, nucleotide metabolism, and vitamin B metabolism. Fluctuating levels of phospholipids and nucleotides may contribute to the neurotoxicity of SCCPs, while down regulation of folic acid induced by SCCPs may lead to malformations during early development in laboratory animals.
ENVIRONMENTAL RESEARCH
(2021)
Article
Engineering, Environmental
Yingxin Wu, Jiahui Wu, Zhuohao Wu, Jingyan Zhou, Lingli Zhou, Yang Lu, Xiaowen Liu, Wencheng Wu
Summary: This study investigated the distribution and microbial responses of short-chain chlorinated paraffins (SCCPs) in groundwater beneath a chlorinated paraffins production plant. Results showed SCCPs were predominantly distributed in hotspots in groundwater, originating from CP synthesis. The microbial community in groundwater responded to the contamination by forming a co-occurrence network and potentially cooperated to achieve the dechlorination and mineralization of SCCPs.
Article
Environmental Sciences
Huijuan Li, Duo Bu, Yan Gao, Nali Zhu, Jing Wu, Xiangfeng Chen, Jianjie Fu, Yawei Wang, Aiqian Zhang, Guibin Jiang
Summary: In alpine regions of the southeastern Tibetan Plateau, short chain chlorinated paraffins (SCCPs) show a clear altitudinal gradient in lichen samples, with a high bioconcentration factor.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2021)
Article
Environmental Sciences
Qiaofeng Ai, Peixuan Zhang, Lirong Gao, Xin Zhou, Yang Liu, Di Huang, Lin Qiao, Jiyuan Weng, Minghui Zheng
Summary: This study investigated the concentrations, congener group profiles, and air-soil exchange of short-chain and medium-chain chlorinated paraffins in a contaminated area in Zhoushan, China. The results showed that CPs were found at higher concentrations in soil samples near shipyards, with chlorinated decane and undecane and penta-, hexa-, and hepta-chlorinated CPs being enriched in the air samples. SCCPs and MCCPs dominated the air-soil exchange.
Article
Engineering, Environmental
Quanyun Ye, Qingmei Song, Jingyan Zhou, Yingxin Wu, Yue Zhou, Jie Zhang, Wencheng Wu
Summary: Short chain chlorinated paraffins (SCCPs) have adverse effects on soil organisms and humans. This study investigated the behavior and fate of SCCPs during advanced oxidation processes (AOPs) in contaminated soil. Results showed that the SCCPs could be effectively degraded within 120 hours by four common oxidants. The relative abundance of certain SCCP congeners increased while others decreased after the oxidation treatment. DFT calculations explained these observations and showed that chlorine atomic percentage had a significant negative correlation with the degradation of SCCP congeners.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Environmental Sciences
Takashi Fujimori, Masahiro Ogura, Akifumi Eguchi, Masaki Takaoka
Summary: The metal sodium dispersion method effectively dechlorinated wax samples containing SCCPs, achieving a destruction efficiency of over 99.999%. Variations in the wax's initial concentrations and Na/wax ratios did not impact the results. The main reaction products in the reaction liquid were identified as aliphatic compounds after dechlorination.
Article
Environmental Sciences
Wenjie Ding, Zixuan Zhao, Yudan Zheng, Rui Wang, Zeyao Zhang, Ziyang Zhang, Xiangdong Wang, Shali Yu, Lei Liu, Rongrong Huang, Xinyuan Zhao, Qiyun Wu
Summary: In this study, SCCP exposure was shown to induce astrocyte proliferation and activation via the JAK2/STAT3 signaling pathway. These findings contribute to the understanding of the molecular mechanism underlying SCCP-induced neurotoxicity.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Engineering, Environmental
Jianzhong Yu, Qing Tang, Ge Yin, Weifang Chen, Jitao Lv, Lingxiangyu Li, Chenghao Zhang, Yunxiang Ye, Xijiao Song, Xueping Zhao, Tao Tang, Changpeng Zhang, Lixi Zeng, Zhenlan Xu
Summary: This study investigates the absorption and translocation mechanisms of short chain chlorinated paraffins (SCCPs) in plants. The research finds that SCCPs are strongly absorbed by roots but have limited translocation to shoots. The hydrophobicity and molecular size of SCCPs influence their uptake and translocation. A temperature and metabolic inhibitor inhibit the root uptake of SCCPs, supporting the involvement of an active energy-dependent process. SCCPs at environmentally relevant concentrations do not impact root morphology and chlorophyll contents, but they do cause changes in cellular ultrastructure and increase superoxide dismutase activity.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Environmental Sciences
Jingwen Huang, Lei Zhao, Yumeng Shi, Xiaowen Zeng, Wenwen Sun, Xianglong Zhao, Ruqing Liu, Qizhen Wu, Guanghui Dong, Da Chen, Xiaotu Liu
Summary: The present study quantified and profiled short-chain chlorinated paraffins (SCCPs), medium-chain chlorinated paraffins (MCCPs), and long-chain chlorinated paraffins (LCCPs) in PM2.5 samples collected from 96 schools in the Pearl River Delta of South China. The concentrations of SCCPs, MCCPs, and LCCPs ranged from 0.832-109, 1.02-110, and 0.173-17.4 ng/m3, respectively, with a detection rate over 90%. The dominant congener groups were C13Cl6-8, C14Cl7-8, and C18Cl7-9 for SCCPs, MCCPs, and LCCPs, respectively. Seasonal and spatial variations were observed, with higher concentrations of SCCPs and MCCPs in summer and higher concentrations of LCCPs in winter. Exposure risk assessment suggested no significant health risk from exposure to PM2.5-associated chlorinated paraffins.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Jakub Tomasko, Ondrej Parizek, Jana Pulkrabova
Summary: This study selected clothing as the research object because it is produced in large quantities worldwide and is worn for long periods in direct contact with human skin. Short- and medium-chain chlorinated paraffins (SCCPs and MCCPs) were found in all samples, with higher concentrations in garments with a substantial proportion of synthetic fibers. The effect of washing in the washing machine varied among individual samples.
ENVIRONMENTAL POLLUTION
(2023)
Article
Engineering, Environmental
Weifang Chen, Xingwang Hou, Xiaowei Mao, Suning Jiao, Linfeng Wei, Yaotian Wang, Jiyan Liu, Guibin Jiang
Summary: This study elaborates the comprehensive environmental transformation of short-chain chlorinated paraffins (SCCPs) in a rice seedling exposure system. The selected congener of SCCPs, CP-4, was quickly absorbed, translocated, and phytovolatilized by seedlings. The transformation of CP-4 was mainly attributed to degradation by rhizosphere microorganisms, root exudates, and abiotic factors, with a majority being phytotransformed by rice seedlings. A total of 61 transformation products were identified through complex pathways.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Nobuyasu Hanari, Takeshi Nakano
Summary: Chlorinated paraffins (CPs) are industrial chemicals primarily used in metalworking fluids. Short-chain chlorinated paraffins (SCCPs) are a famous environmental pollutant, and reliable quantification of SCCPs has been a critical issue due to the large number of SCCP isomers. This study developed a novel SCCP formulation as a candidate reference material and evaluated the reliability of gas chromatography mass spectrometry (GC/MS) and liquid chromatography mass spectrometry (LC/MS) methods. The results showed comparable concentrations of SCCPs from GC and LC, indicating the effectiveness of the candidate reference material for quantification and evaluation.
Article
Engineering, Environmental
Yang Wu, Shutao Gao, Xiangying Zeng, Yi Liang, Zhiyang Liu, Lixiong He, Jing Yuan, Zhiqiang Yu
Summary: This study collected indoor dust in Wuhan, China and investigated the occurrence and composition of chlorinated paraffins (CPs) as well as the potential human health risks through dust ingestion and dermal absorption. The results showed that CPs with different carbon chain lengths and chlorine contents were present in indoor dust, with medium-chain CPs being the main components. Based on the measured concentrations, the human health risks posed by CPs to local residents were limited.
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
(2023)
Article
Chemistry, Multidisciplinary
Qiao Xue, Xian Liu, Wenxiao Pan, Aiqian Zhang, Jianjie Fu, Guibin Jiang
Summary: This study investigated the allosteric effect of the S protein of SARS-COV-2 and found that binding of ACE2 caused movement and exposure of certain regions. It was also observed that SARS-COV-2 has higher binding affinity to ACE2 compared to SARS-COV due to a specific mutation. These findings provide a theoretical basis for understanding SARS-COV-2 infection and developing detection tools.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Engineering, Environmental
Ben Yu, Lin Yang, Hongwei Liu, Cailing Xiao, Duo Bu, Qiangying Zhang, Jianjie Fu, Qianggong Zhang, Zhiyuan Cong, Yong Liang, Ligang Hu, Yongguang Yin, Jianbo Shi, Guibin Jiang
Summary: This study provides direct evidence from mercury isotopes to reveal the distinct patterns of transboundary transport of atmospheric mercury to the Tibetan Plateau shaped by landforms and climates, which is critical for understanding the biogeochemical cycling of mercury in high-altitude regions.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Biochemical Research Methods
Huizhi Li, Ri Wu, Qiongzheng Hu, Xiangfeng Chen, T-W Dominic Chan
Summary: A new integrated matrix deposition device with synchronous solvent nebulization was developed for MALDI-mass spectrometry imaging, improving efficiency and quality in imaging of protein and small metabolite distributions in mouse brain tissue sections. The device demonstrated enhanced sensitivity and image quality compared to conventional methods, showing its utility in MALDI-MSI applications.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Article
Engineering, Environmental
Kai Huang, Yili Li, Duo Bu, Jie Fu, Meilin Wang, Wei Zhou, Luyao Gu, Yilin Fu, Zhiyuan Cong, Boyuan Hu, Jianjie Fu, Aiqian Zhang, Guibin Jiang
Summary: This study investigated the occurrence and trophic transfer of short-chain PFASs in a terrestrial food chain and found that PFASs exhibit biomagnification in the food chain. The study also suggested that bird feathers can serve as indicators of PFAS exposure.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Mei Zhao, Limei Luo, Yongxian Guo, Binglu Zhao, Xiangfeng Chen, Xingang Shi, Mashooq Khan, Jin-Ming Lin, Qiongzheng Hu
Summary: This study presents a novel amylase sensor based on pH paper strips for quantitative detection of AMS. The sensor showed high sensitivity with a detection limit of 0.017 U/mL and excellent specificity. It was successfully used for distinguishing amylase levels in healthy individuals and acute pancreatitis patients.
Article
Biochemical Research Methods
H-T Kitty Wong, Xiangfeng Chen, Ri Wu, Y-L Elaine Wong, Y-L Winnie Hung, T-W Dominic Chan
Summary: This study evaluates three dissociation methods, including collision-induced dissociation (CID), electron capture dissociation (ECD), and electronic excitation dissociation (EED), for the dissociation of doubly charged glycans. It found that CID of magnesiated glycans and EED of sodiated glycans can provide extensive structural information.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Article
Biochemical Research Methods
H. -T. Kitty Wong, Simin Zhang, T. -y Lui, D. Hu, T. -W. Dominic Chan, Xiangfeng Chen
Summary: This study systematically compared three dissociation methods, collision-induced dissociation (CID), electron capture dissociation (ECD), and electronic excitation dissociation (EED), for structural characterization of doubly charged glycopeptide. The results showed that EED of magnesiated species could be used as a one-step dissociation method for comprehensive structural analysis of glycopeptides.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Article
Engineering, Environmental
Jie Fu, Kehan Fu, Boyuan Hu, Wei Zhou, Yilin Fu, Luyao Gu, Qinghua Zhang, Aiqian Zhang, Jianjie Fu, Guibin Jiang
Summary: This study investigated the sources and environmental behavior of organophosphate esters (OPEs) in the Arctic, specifically in proglacial and ocean sediments. The results showed lower concentrations of OPEs in proglacial sediments compared to ocean sediments, indicating different sources and influences. Proglacial sediments were predominantly affected by long-range atmospheric transport (LRAT), while ocean sediments were influenced by LRAT, oceanic transport, and human activities.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Analytical
T. -Y. Lui, Xiangfeng Chen, Simin Zhang, Danna Hu, T. -W. Dominic Chan
Summary: Reproducible peptide oxidation was observed using a homebuilt LMJ-SSP platform. The oxidation was induced by liquid-solid electrification processes during droplet drying on a solid surface. To minimize oxidation, decreasing water content in the sample solution, avoiding hydroxyl-functionalized substrates, and adding an antioxidant to the sample solution were recommended. These findings are applicable to MS methods involving drying micro-liters of sample solution on suitable substrates.
ANALYTICAL CHEMISTRY
(2023)
Editorial Material
Engineering, Environmental
Xuezhi Yang, Haonan Wen, Yue Lin, Haiyan Zhang, Yin Liu, Jianjie Fu, Qian Liu, Guibin Jiang
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
Xian Liu, Yunhe Guo, Wenxiao Pan, Qiao Xue, Jianjie Fu, Guangbo Qu, Aiqian Zhang
Summary: This study proposes a deep learning model based on the graph convolutional network (GCN) that can predict the effect of exogenous substances on the transcriptional expression of the ACE2 gene. Compared to other machine learning models, it achieves an area under receiver operating characteristic curve (AUROC) of 0.712 and 0.703 on the validation and internal test set, respectively. Additionally, qPCR experiments provide supporting evidence for indoor air pollutants identified by the GCN model. The proposed methodology can be applied to predict the effect of environmental chemicals on the gene transcription of other virus receptors as well.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Ya-xin Hao, Min-li Yang, Xiang-feng Chen, Feng Zhang, Na Li, Mu-yi He, Mei-xia Xu
Summary: A magnetic molecularly imprinted polymer (MMIP) coupled nanospray ion source was developed for analysis of cephalosporin antibiotics in food samples. The device combines the advantages of high extraction efficiency of MSPE, unique selectivity of MIPs, and fast analysis speed of AIMS. The developed methods showed high sensitivities, good linearity, and precision with recoveries ranging from 72.6% to 115.5% in milk, egg, and beef samples.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Biochemical Research Methods
T. -W. Dominic Chan, Xiangfeng Chen, Simin Zhang, H. -T. Kitty Wong, T. -y Lui, Danna Hu
Summary: A performance enhanced CaptiveSpray differential ion mobility device was designed and constructed by incorporating a circular channel and a gas flow homogenizing channel (GFHC) between the CaptiveSpray ion source and planar differential ion mobility spectrometry (DMS). The optimal flared entrance greatly reduces gas flow velocity at the inlet region, which assists in reducing disparities between the minimum and maximum gas velocity along the x-axis. The circular electrode with channels along the x-and y-axis focuses the incoming ions from the CaptiveSpray source into the DMS channel, leading to substantial signal enhancement with a concomitant reduction of the peak width in the ionogram.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Article
Environmental Sciences
Huijuan Li, Jinpeng Chen, Tao Sun, Ru-Song Zhao, Xiangfeng Chen, Jianjie Fu
Summary: This study scientifically assesses the environmental risks of secondary CPs caused by reclaimed water and sludge disposal. It examines the occurrences of SCCPs and MCCPs in a sewage treatment plant, finding that sorption onto sludge is the main fate of CPs in wastewater treatment.
Article
Geosciences, Multidisciplinary
Shichang Kang, Yulan Zhang, Pengfei Chen, Junming Guo, Qianggong Zhang, Zhiyuan Cong, Susan Kaspari, Lekhendra Tripathee, Tanguang Gao, Hewen Niu, Xinyue Zhong, Xintong Chen, Zhaofu Hu, Xiaofei Li, Yang Li, Bigyan Neupane, Fangping Yan, Dipesh Rupakheti, Chaman Gul, Wei Zhang, Guangming Wu, Ling Yang, Zhaoqing Wang, Chaoliu Li
Summary: This study presents a systematic dataset of carbonaceous aerosols from the Third Pole region, including aerosols, glaciers, snow cover, precipitation, and lake sediment. The dataset provides valuable insights into the linkages between atmospheric pollutants and cryospheric changes.
EARTH SYSTEM SCIENCE DATA
(2022)
