Type 2 Diabetes: Multiple Genes, Multiple Diseases

Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis

(2019) Seth A. Sharp et al.   DIABETES CARE

Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes

(2019) Chirag M. Lakhani et al.   NATURE GENETICS

Disease progression and treatment response in data-driven subgroups of type 2 diabetes compared with models based on simple clinical features: an analysis using clinical trial data

(2019) John M Dennis et al.   Lancet Diabetes & Endocrinology

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

(2018) Sílvia Bonàs-Guarch et al.   Nature Communications

Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank

(2018) Nicholas J Thomas et al.   Lancet Diabetes & Endocrinology

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables

(2018) Emma Ahlqvist et al.   Lancet Diabetes & Endocrinology

ISPAD 2018 Consensus Guidelines: The diagnosis and management of monogenic diabetes in children and adolescents

(2018) Andrew T. Hattersley et al.   PEDIATRIC DIABETES

Mice harboring the humanSLC30A8R138X loss-of-function mutation have increased insulin secretory capacity

(2018) Sandra Kleiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis

(2018) Miriam S. Udler et al.   PLOS MEDICINE

BH3-Mimetic Drugs: Blazing the Trail for New Cancer Medicines

(2018) Delphine Merino et al.   CANCER CELL

2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2019

(2018)   DIABETES CARE

A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody–Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy

(2018) Anita L. Grubb et al.   DIABETES CARE

Classification of common human diseases derived from shared genetic and environmental determinants

(2017) Kanix Wang et al.   NATURE GENETICS

DNA Damage and Repair Biomarkers of Immunotherapy Response

(2017) Kent W. Mouw et al.   Cancer Discovery

The Time Is Right for a New Classification System for Diabetes: Rationale and Implications of the β-Cell–Centric Classification Schema

(2016) Stanley S. Schwartz et al.   DIABETES CARE

Identification of type 2 diabetes subgroups through topological analysis of patient similarity

(2015) Li Li et al.   Science Translational Medicine

The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium

(2015) Gonneke Willemsen et al.   Twin Research and Human Genetics

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

(2014) Jason Flannick et al.   NATURE GENETICS

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

(2014) H. Mahdessian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity

(2013) Antigone S. Dimas et al.   DIABETES

Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico

(2013)   NATURE

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study

(2011) P. Almgren et al.   DIABETOLOGIA

Maturity-onset diabetes of the young (MODY): how many cases are we missing?

(2010) B. M. Shields et al.   DIABETOLOGIA

Syndromes of Ketosis-Prone Diabetes Mellitus

(2008) Ashok Balasubramanyam et al.   ENDOCRINE REVIEWS

Clinical implications of a molecular genetic classification of monogenic β-cell diabetes

(2008) Rinki Murphy et al.   Nature clinical practice. Endocrinology & metabolism