Article
Clinical Neurology
Anna C. Pfalzer, Kelly H. Watson, Abagail E. Ciriegio, Lisa Hale, Spencer Diehl, Katherine E. McDonell, Cindy Vnencak-Jones, Elizabeth Huitz, Abigail Snow, Marissa C. Roth, Cara S. Guthrie, Heather Riordan, Jeffrey D. Long, Bruce E. Compas, Daniel O. Claassen
Summary: This study provides strong evidence that impairments in executive function occur as early as the second decade of life in individuals with Huntington disease, well before the anticipated motor onset.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Clinical Neurology
Maritza N. Taylor, Sandra Tambi, Neil D. Almeida, Steven B. Housley, Renee M. Reynolds
Summary: Intrameningeal cysts are rare lesions without definitive etiologies that can involve the dura or arachnoid mater. This case study describes a 17-year-old girl with symptoms including neck and back pain, numbness, and weakness, which ultimately led to surgical exploration revealing fluid collection within the dural layers. An intracystic blood patch was performed, resulting in near-complete resolution of the lesion and return of neurologic function.
WORLD NEUROSURGERY
(2022)
Review
Clinical Neurology
Yu-bo Wang, Dan -hua Wang, Shuang-lin Deng
Summary: This paper conducted a systematic review of secondary spinal arachnoid cysts and found that they have diverse etiologies and are difficult to treat. Although fenestration/marsupialization is a common treatment method, the recurrence rate is high. For unresectable cysts, shunting into a body cavity (such as the pleural or peritoneal cavity) may be an alternative therapy.
Article
Clinical Neurology
Giorgia Coratti, Jacopo Lenkowicz, Maria Carmela Pera, Adele D'Amico, Claudio Bruno, Consolato Gulli, Noemi Brolatti, Marina Pedemonte, Laura Antonaci, Martina Ricci, Anna Capasso, Gianpaolo Cicala, Costanza Cutrona, Roberto de Sanctis, Sara Carnicella, Nicola Forcina, Michela Cateruccia, Maria Beatrice Damasio, Luca Labianca, Francesca Manfroni, Antonio Leone, Enrico Bertini, Marika Pane, Stefano Patarnello, Vincenzo Valentini, Eugenio Mercuri
Summary: This study aims to evaluate potential differences in scoliosis progression between treated and untreated type II spinal muscular atrophy (SMA) patients. The results indicate that pharmacological treatment, if initiated early, may slow down the progression of scoliosis in SMA patients.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Clinical Neurology
Maritza N. Taylor, Sandra Tambi, Neil D. Almeida, Steven B. Housley, Renee M. Reynolds
Summary: Background: Intrameningeal cysts are rare lesions that can involve the dura or arachnoid mater. Although spinal arachnoid cysts have been described, little is known about purely dural-based cystic lesions. We present a case of a 17-year-old girl with radiculopathy and myelopathy symptoms, in which extensive investigations failed to identify an obvious etiology. Surgical exploration revealed intradural fluid collection rather than an epidural leak. The patient achieved near-complete resolution of symptoms and neurologic function after an intracystic blood patch.
WORLD NEUROSURGERY
(2022)
Article
Pathology
Tatsuro Maehara, Ayako Yamazaki, Reika Kawabata-Iwakawa, Kohei Fukuoka, Ayumi Akazawa, Naoki Okura, Masahiko Nishiyama, Farshad Nassiri, Justin Z. Wang, Gelareh Zadeh, Kenichiro Kikuta, Hidehiro Oka, Junko Hirato, Hideaki Yokoo, Sumihito Nobusawa
Summary: This study reports previously undescribed lesions in NF1 patients, which were initially thought to be non-neoplastic but were found to be whitish jelly-like masses during surgery. Although histological examination suggested a neoplastic nature, molecular analysis and DNA methylation analysis indicated that these lesions may represent rare hyperplasia of arachnoid trabecular cells associated with NF1.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY
(2023)
Review
Medicine, General & Internal
James B. Badenoch, Isabella Conti, Emma R. Rengasamy, Cameron J. Watson, Matthew Butler, Zain Hussain, Ben Carter, Alasdair G. Rooney, Michael S. Zandi, Glyn Lewis, Anthony S. David, Catherine F. Houlihan, Ava Easton, Benedict D. Michael, Krutika Kuppalli, Timothy R. Nicholson, Thomas A. Pollak, Jonathan P. Rogers
Summary: This systematic review and meta-analysis examined the neuropsychiatric presentations of monkeypox infection and found evidence of severe neurological complications and nonspecific neurological features. However, there is limited evidence regarding the psychiatric presentations or sequelae of the virus.
Article
Clinical Neurology
Alan J. Carson, Laura McWhirter
Summary: This review discusses the application of cognitive behavioral therapy (CBT) in neurological disorders, emphasizing the interrelationship among symptoms, emotions, thoughts, and behaviors, and the potential to reduce symptoms or emotional distress through changing thoughts or behaviors. It also outlines methodological issues in CBT intervention studies and summarizes the evidence base for CBT's use in various neurological disorders.
SEMINARS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Ahmed K. Ahmed, Bhrugun Anisetti, Thien Huynh, Amit Agarwal, Vivek Gupta, Amit Desai, Rahul Singh, Prasanna Vibhute
Summary: This study investigated the demographics and imaging spectrum of spinal extradural arachnoid cysts (SEDACs) and compared them with previous studies. The majority of the cysts were incidental findings, located in the thoracic spine dorsal to the thecal sac, and the most common presenting symptoms were back pain and radiculopathy. Surgical excision may be the best treatment for symptomatic lesions.
Review
Clinical Neurology
A. Karim Ahmed, Alan R. R. Cohen
Summary: The purpose of this review article is to outline the natural history, pathogenesis, anatomic considerations, and surgical decision-making in caring for patients with intracranial arachnoid cysts. A comprehensive review of relevant articles and the author's own experience was conducted. Arachnoid cysts are congenital lesions characterized by specific features. The underlying etiology is not entirely known, and they are associated with various genetic conditions. Most intracranial arachnoid cysts are incidentally found, primarily in the middle cranial fossa. This article provides a comprehensive overview of the management of patients with intracranial arachnoid cysts.
CHILDS NERVOUS SYSTEM
(2023)
Editorial Material
Clinical Neurology
Tshibambe Nathanael Tshimbombu, Seo Ho Song, Diana M. Rojas-Soto, Okitundu-Luwa E-Andjafono Daniel
Summary: The Neuro-Psycho-Pathology Center in the Democratic Republic of Congo is a large neuropsychiatric clinic that aims to integrate various disciplines in order to address the brain and behavioral health needs of Congolese patients. However, due to financial and resource shortages, the center is currently only functioning at 10% of its capacity.
WORLD NEUROSURGERY
(2022)
Article
Multidisciplinary Sciences
Rajan Kashyap, Goi Khia Eng, Sagarika Bhattacharjee, Bhanu Gupta, Roger Ho, Cyrus S. H. Ho, Melvyn Zhang, Rathi Mahendran, Kang Sim, S. H. Annabel Chen
Summary: The study revealed altered brain organization in patients with OCD compared to healthy controls using individual-based approaches to maximize the identification of underlying network-based features specific to the OCD group. This suggests differences in functional architecture in patients with OCD and control groups, indicating potential unique patterns in OCD pathophysiology.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Letizia Maria Cupini, Paolo Calabresi
Summary: Giacomo Balla, an Italian Futurist painter, had a profound interest in neurophysiological and neurological sciences, which greatly influenced his personal painting style. His famous artworks serve as historical records of the neuroscience environment at the turn of the 20th century.
Article
Clinical Neurology
Rinat A. Sufianov, Malika M. Abdumazhitova, Rakhmonzhon R. Rustamov, Roy T. Daniel, Luciano Mastronardi, Gennady E. Chmutin, Marcio S. Rassi, Luis A. B. Borba, Albert A. Sufianov
Summary: This study describes the clinical outcomes of an innovative minimally invasive endoscopic technique for the treatment of middle cranial fossa arachnoid cysts. The use of a mini endoscope allows for better examination and treatment of the cysts, resulting in a high success rate.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Tina Mainka, Jan-Frederik Fischer, Julius Huebl, Alexandra Jung, Dinah Lier, Alexandra Mosejova, Matej Skorvanek, Tom J. de Koning, Andrea A. Kuehn, Peter Freisinger, Athanasia Ziagaki, Christos Ganos
Summary: This study identified a range of neurological and neuropsychiatric symptoms in late-treated PKU adults, including developmental delay, intellectual disability, movement disorders, and neuropsychiatric characteristics. The presence of these symptoms in adults should raise suspicion for PKU, and adherence to treatment can help alleviate symptom severity.
PARKINSONISM & RELATED DISORDERS
(2021)
Letter
Clinical Neurology
Jeremy D. Schmahmann, Mark G. Vangel, Franziska Hoche, Xavier Guell, Janet C. Sherman
Article
Computer Science, Interdisciplinary Applications
Mathew Birdsall Abrams, Jan G. Bjaalie, Samir Das, Gary F. Egan, Satrajit S. Ghosh, Wojtek J. Goscinski, Jeffrey S. Grethe, Jeanette Hellgren Kotaleski, Eric Tatt Wei Ho, David N. Kennedy, Linda J. Lanyon, Trygve B. Leergaard, Helen S. Mayberg, Luciano Milanesi, Roman Moucek, J. B. Poline, Prasun K. Roy, Stephen C. Strother, Tong Boon Tang, Paul Tiesinga, Thomas Wachtler, Daniel K. Wojcik, Maryann E. Martone
Summary: There is a great need for coordination around standards and best practices in neuroscience to address challenges in data science. Developing community standards and gaining their adoption is difficult, as the current landscape is characterized by a lack of robust, validated standards and a plethora of underdeveloped and underutilized standards and best practices. An independent organization, the International Neuroinformatics Coordinating Facility (INCF), is dedicated to promoting data sharing in neuroscience and has implemented procedures for evaluating and endorsing community standards and best practices.
Correction
Computer Science, Interdisciplinary Applications
Mathew Birdsall Abrams, Jan G. Bjaalie, Samir Das, Gary F. Egan, Satrajit S. Ghosh, Wojtek J. Goscinski, Jeffrey S. Grethe, Jeanette Hellgren Kotaleski, Eric Tatt Wei Ho, David N. Kennedy, Linda J. Lanyon, Trygve B. Leergaard, Helen S. Mayberg, Luciano Milanesi, Roman Moucek, J. B. Poline, Prasun K. Roy, Stephen C. Strother, Tong Boon Tang, Paul Tiesinga, Thomas Wachtler, Daniel K. Wojcik, Maryann E. Martone
Article
Clinical Neurology
Holger Hengel, Peter Martus, Jennifer Faber, Hector Garcia-Moreno, Nita Solanky, Paola Giunti, Thomas Klockgether, Kathrin Reetz, Bart P. van de Warrenburg, Luis Pereira de Almeida, Magda M. Santana, Cristina Januario, Patrick Silva, Andreas Thieme, Jon Infante, Jeroen de Vries, Manuela Lima, Ana F. Ferreira, Khalaf Bushara, Heike Jacobi, Chiadi Onyike, Jeremy D. Schmahmann, Jeannette Huebener-Schmid, Matthis Synofzik, Ludger Schoels
Summary: The study found that patients with SCA3 had lower levels of physical activity and alcohol consumption compared to controls. Less physical activity and alcohol abstinence were associated with more severe disease, but did not affect disease progression rates or age of onset.
MOVEMENT DISORDERS
(2022)
Article
Clinical Neurology
He Zhou, Hung Nguyen, Ana Enriquez, Louie Morsy, Michael Curtis, Timothy Piser, Christopher Kenney, Christopher D. Stephen, Anoopum S. Gupta, Jeremy D. Schmahmann, Ashkan Vaziri
Summary: The study utilized wearable sensors to objectively measure motor impairment in SCA patients during gait and balance assessments, distinguishing them from healthy controls. Linear regression models demonstrated moderate-to-strong correlation with SARA and BARS2 scores.
NEUROLOGICAL SCIENCES
(2022)
Article
Biology
Alejandro de la Vega, Roberta Rocca, Ross W. Blair, Christopher J. Markiewicz, Jeff Mentch, James D. Kent, Peer Herholz, Satrajit S. Ghosh, Russell A. Poldrack, Tal Yarkoni
Summary: Neuroscout is an end-to-end platform for analyzing naturalistic fMRI data, which automatically annotates stimuli from multiple ecologically-valid datasets and reduces the burden of reproducible research. Through validating the automatic feature extraction approach, it has the potential to support more robust fMRI research and democratize fMRI research.
Article
Biology
Oliver Rubel, Andrew Tritt, Ryan Ly, Benjamin K. Dichter, Satrajit Ghosh, Lawrence Niu, Pamela Baker, Ivan Soltesz, Lydia Ng, Karel Svoboda, Loren Frank, Kristofer E. Bouchard
Summary: This article introduces the design and implementation principles of a language for neurophysiology data and demonstrates the impact of NWB software in unifying the description of neurophysiology data across different species, enabling the reproducibility, interchangeability, and reusability of the data.
Biographical-Item
Neurosciences
Jeremy D. Schmahmann
JOURNAL OF COMPARATIVE NEUROLOGY
(2023)
Article
Psychiatry
Mai Uchida, Qasim Bukhari, Maura DiSalvo, Allison Green, Giulia Serra, Chloe Hutt Vater, Satrajit S. Ghosh, Stephen V. Faraone, John D. E. Gabrieli, Joseph Biederman
Summary: This study developed a quantitative predictive model for bipolar disorder using machine learning algorithms and clinical data. The predictors included behavioral problems, school functioning, and anxiety/depression and aggression scales. The results have important clinical and scientific implications for assessing the risk of bipolar disorder in children.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Biochemical Research Methods
Rastko Ciric, William H. H. Thompson, Romy Lorenz, Mathias Goncalves, Eilidh E. E. MacNicol, Christopher J. J. Markiewicz, Yaroslav O. O. Halchenko, Satrajit S. S. Ghosh, Krzysztof J. J. Gorgolewski, Russell A. A. Poldrack, Oscar Esteban
Summary: This article introduces TemplateFlow as a publicly available framework for human and non-human brain models. It combines an open database with software to enable scientists to share their resources under FAIR principles, allowing multifaceted brain analyses.
Article
Neurosciences
Usman Mahmood, Zening Fu, Satrajit Ghosh, Vince Calhoun, Sergey Plis
Summary: This research combines the strengths of deep learning and functional connectivity methods, while also addressing their limitations. By introducing a directed graph layer in a deep learning architecture, we propose a highly interpretable model that is able to accurately discriminate different brain network connections, leading to significant improvements in disease and gender prediction.
Article
Clinical Neurology
Nicole M. Eklund, Jessey Ouillon, Vineet Pandey, Christopher D. Stephen, Jeremy D. Schmahmann, Jeremy Edgerton, Krzysztof Z. Gajos, Anoopum S. Gupta
Summary: This study tested the use of wearable sensors and a computer mouse task as reliable and meaningful motor measures for potential use in clinical trials. The results showed that these measures were strongly correlated with patient function and ataxia rating scales, indicating their potential as sensitive motor outcome measures.
BRAIN COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Priyanka Subash, Alex Gray, Misque Boswell, Samantha L. Cohen, Rachael Garner, Sana Salehi, Calvary Fisher, Samuel Hobel, Satrajit Ghosh, Yaroslav Halchenko, Benjamin Dichter, Russell A. Poldrack, Chris Markiewicz, Dora Hermes, Arnaud Delorme, Scott Makeig, Brendan Behan, Alana Sparks, Stephen R. Arnott, Zhengjia Wang, John Magnotti, Michael S. Beauchamp, Nader Pouratian, Arthur W. Toga, Dominique Duncan
Summary: This paper compares four freely available intracranial neuroelectrophysiology data repositories and describes their tools for storage, sharing, and reanalysis, as well as the data standards they implement to facilitate data accessibility and collaboration within the neuroscience community.
Review
Neurosciences
Jeremy D. Schmahmann
Summary: The cerebellum plays a role in cognition and emotion, in addition to motor control. Clinical observations and studies have shown its connectivity with various brain areas involved in autonomic control, sensorimotor integration, vestibular function, and emotions. Understanding the cerebellum's involvement in cognition and emotion is crucial for studying higher order deficits and neuropsychiatric disorders related to cerebellar diseases.
Article
Neurosciences
Michele H. Potashman, Miranda L. Mize, Melissa W. Beiner, Samantha Pierce, Vladimir Coric, Jeremy D. Schmahmann
Summary: This study created a concept library of symptoms and activities impacted by ataxia based on surveys and cognitive debrief data. These concepts were then mapped onto 4 clinical measures of ataxia, showing that ataxia rating scales reflect patient reported symptoms and impact of illness. The results validate the relevance of these scales and emphasize the importance of considering multiple items to represent the totality of the patient experience.