CCL21/CCR7 signaling in macrophages promotes joint inflammation and Th17-mediated osteoclast formation in rheumatoid arthritis

The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy

(2018) Georgios L. Moschovakis et al.   Cellular & Molecular Immunology

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7+Progenitors to the Thymus

(2018) Emilie J. Cosway et al.   JOURNAL OF IMMUNOLOGY

IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation

(2018) Shankar Revu et al.   Cell Reports

The Role of Macrophages in the Response to TNF Inhibition in Experimental Arthritis

(2017) Qi-Quan Huang et al.   JOURNAL OF IMMUNOLOGY

Associations between CCL21 gene polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis

(2017) Guomin Li et al.   RHEUMATOLOGY INTERNATIONAL

Th17 Cytokines Regulate Osteoclastogenesis in Rheumatoid Arthritis

(2015) Kyoung-Woon Kim et al.   AMERICAN JOURNAL OF PATHOLOGY

Anti-CCL21 Antibody Attenuates Infarct Size and Improves Cardiac Remodeling After Myocardial Infarction

(2015) Yi Jiang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Ligation of TLR5 Promotes Myeloid Cell Infiltration and Differentiation into Mature Osteoclasts in Rheumatoid Arthritis and Experimental Arthritis

(2014) Seung-jae Kim et al.   JOURNAL OF IMMUNOLOGY

The chemotaxis of M1 and M2 macrophages is regulated by different chemokines

(2014) Wenjuan Xuan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Upregulated baseline plasma CCL19 and CCR7 cell-surface expression on monocytes in early rheumatoid arthritis normalized during treatment and CCL19 correlated with radiographic progression

(2013) T Ellingsen et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort

(2012) John Bowes et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of the CCL21 and CCR7 pathways in rheumatoid arthritis angiogenesis

(2012) Sarah R. Pickens et al.   ARTHRITIS AND RHEUMATISM

TLR5, a Novel and Unidentified Inflammatory Mediator in Rheumatoid Arthritis that Correlates with Disease Activity Score and Joint TNF-  Levels

(2012) N. D. Chamberlain et al.   JOURNAL OF IMMUNOLOGY

oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21

(2012) Thomas Nickel et al.   MEDIATORS OF INFLAMMATION

Characterization of CCL19 and CCL21 in rheumatoid arthritis

(2011) Sarah R. Pickens et al.   ARTHRITIS AND RHEUMATISM

Local expression of interleukin-27 ameliorates collagen-induced arthritis

(2011) Sarah R. Pickens et al.   ARTHRITIS AND RHEUMATISM

SLC/CCR7 Stimulates the Proliferation of BMDCs by the pNF-κB p65 Pathway

(2009) Shuang Zhou et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

CCR 7 Ligands Are Required for Development of Experimental Autoimmune Encephalomyelitis through Generating IL-23-Dependent Th17 Cells

(2009) T. Kuwabara et al.   JOURNAL OF IMMUNOLOGY

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

(2008) Soumya Raychaudhuri et al.   NATURE GENETICS