Downregulation of FOXO3a by DNMT1 promotes breast cancer stem cell properties and tumorigenesis
出版年份 2019 全文链接
标题
Downregulation of FOXO3a by DNMT1 promotes breast cancer stem cell properties and tumorigenesis
作者
关键词
-
出版物
CELL DEATH AND DIFFERENTIATION
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-07-11
DOI
10.1038/s41418-019-0389-3
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- FOXO family in regulating cancer and metabolism
- (2018) Jian Ma et al. SEMINARS IN CANCER BIOLOGY
- FoxO transcription factors in cancer metabolism
- (2018) Raj Kumar Yadav et al. SEMINARS IN CANCER BIOLOGY
- The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance
- (2018) Shang Yao et al. SEMINARS IN CANCER BIOLOGY
- Critical role of FOXO3a in carcinogenesis
- (2018) Ying Liu et al. Molecular Cancer
- The FOXO3/PGC-1β signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma
- (2017) Motofumi Kumazoe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self-renewal of breast cancer stem cells
- (2017) N Yang et al. ONCOGENE
- FoxM1: Repurposing an oncogene as a biomarker
- (2017) Deeptashree Nandi et al. SEMINARS IN CANCER BIOLOGY
- DNA Methylation in Cancer and Aging
- (2016) M. Klutstein et al. CANCER RESEARCH
- Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth
- (2016) R. Pathania et al. CANCER RESEARCH
- Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells
- (2016) K Tominaga et al. ONCOGENE
- FOXO3 is essential for CD44 expression in pancreatic cancer cells
- (2016) M Kumazoe et al. ONCOGENE
- NF-κB–driven suppression of FOXO3a contributes to EGFR mutation-independent gefitinib resistance
- (2016) Ching-Feng Chiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer
- (2016) C Gong et al. Oncogenesis
- Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner
- (2015) V. V. Prabhu et al. CANCER RESEARCH
- FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells
- (2015) Ai-hua Gong et al. CANCER RESEARCH
- FOXO3a modulates WNT/β-catenin signaling and suppresses epithelial-to-mesenchymal transition in prostate cancer cells
- (2015) Hao Liu et al. CELLULAR SIGNALLING
- The miR-134 attenuates the expression of transcription factor FOXM1 during pluripotent NT2/D1 embryonal carcinoma cell differentiation
- (2015) Yan Chen et al. EXPERIMENTAL CELL RESEARCH
- Essential roles of FoxM1 in Ras-induced liver cancer progression and in cancer cells with stem cell features
- (2015) Dragana Kopanja et al. JOURNAL OF HEPATOLOGY
- CD44 is functionally crucial for driving lung cancer stem cells metastasis through Wnt/β-catenin-FoxM1-Twist signaling
- (2015) Jie Su et al. MOLECULAR CARCINOGENESIS
- A role for cancer stem cells in therapy resistance: Cellular and molecular mechanisms
- (2015) Monica Cojoc et al. SEMINARS IN CANCER BIOLOGY
- DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis
- (2015) Rajneesh Pathania et al. Nature Communications
- An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation
- (2015) Linda Smit et al. Oncotarget
- FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2
- (2015) Yeri Lee et al. PLoS One
- Enriched CD44+/CD24− population drives the aggressive phenotypes presented in triple-negative breast cancer (TNBC)
- (2014) Fei Ma et al. CANCER LETTERS
- The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma
- (2014) Shu-Bin Gao et al. JOURNAL OF HEPATOLOGY
- Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance
- (2014) Hariharan Easwaran et al. MOLECULAR CELL
- DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2
- (2014) H Lopez-Bertoni et al. ONCOGENE
- The mTOR Pathway Controls Cell Proliferation by Regulating the FoxO3a Transcription Factor via SGK1 Kinase
- (2014) Shunsuke Mori et al. PLoS One
- FOXM1: A key oncofoetal transcription factor in health and disease
- (2014) Laura Bella et al. SEMINARS IN CANCER BIOLOGY
- Brief Reports: A Distinct DNA Methylation Signature Defines Breast Cancer Stem Cells and Predicts Cancer Outcome
- (2014) Rita El Helou et al. STEM CELLS
- DNA Methyltransferases: A Novel Target for Prevention and Therapy
- (2014) Dharmalingam Subramaniam et al. Frontiers in Oncology
- The roles of FOXM1 in pancreatic stem cells and carcinogenesis
- (2013) Ming Quan et al. Molecular Cancer
- Foxm1 transcription factor is required for the initiation of lung tumorigenesis by oncogenic KrasG12D
- (2013) I-C Wang et al. ONCOGENE
- FOXO3a loss is a frequent early event in high-grade pelvic serous carcinogenesis
- (2013) K Levanon et al. ONCOGENE
- Targeting cancer stem cells to suppress acquired chemotherapy resistance
- (2013) S J Vidal et al. ONCOGENE
- Foxo3a Expression Is a Prognostic Marker in Breast Cancer
- (2013) Ying Jiang et al. PLoS One
- Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells
- (2012) Hsing-Chen Tsai et al. CANCER CELL
- FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer
- (2011) Hany Onsy Habashy et al. BREAST CANCER RESEARCH AND TREATMENT
- FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis
- (2011) Nu Zhang et al. CANCER CELL
- Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia
- (2011) Sylvain Thépot et al. CELL CYCLE
- FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer
- (2011) C T Karadedou et al. ONCOGENE
- Highly Phosphorylated FOXO3A Is an Adverse Prognostic Factor in Acute Myeloid Leukemia
- (2010) S. M. Kornblau et al. CLINICAL CANCER RESEARCH
- Low expression of Foxo3a is Associated with Poor Prognosis in Ovarian Cancer Patients
- (2009) Min Fei et al. CANCER INVESTIGATION
- Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature
- (2009) Emmanuelle Charafe-Jauffret et al. CANCER RESEARCH
- A New Fork for Clinical Application: Targeting Forkhead Transcription Factors in Cancer
- (2009) J.-Y. Yang et al. CLINICAL CANCER RESEARCH
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer
- (2009) U. B. McGovern et al. MOLECULAR CANCER THERAPEUTICS
- ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation
- (2008) Jer-Yen Yang et al. NATURE CELL BIOLOGY
- The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
- (2008) A. Dubrovska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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