TNF-α promotes human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells through downregulating P38-mediated Occludin expression

Potential pathological role of pro-inflammatory cytokines (IL-6, TNF-α, and IL-17) in xenotransplantation

(2019) Yanli Zhao et al.   XENOTRANSPLANTATION

Porcine IL-6, IL-1β, and TNF-α regulate the expression of pro-inflammatory-related genes and tissue factor in human umbilical vein endothelial cells

(2018) Hanchao Gao et al.   XENOTRANSPLANTATION

Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning

(2017) Hanchao GAO et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Angiopoietin-1 and angiopoietin-2 protect porcine iliac endothelial cells from human antibody-mediated complement-dependent cytotoxicity through phosphatidylinositide 3-kinase/AKT pathway activation

(2017) Hanchao Gao et al.   XENOTRANSPLANTATION

Human IL-6, IL-17, IL-1β, and TNF-α differently regulate the expression of pro-inflammatory related genes, tissue factor, and swine leukocyte antigen class I in porcine aortic endothelial cells

(2017) Hanchao Gao et al.   XENOTRANSPLANTATION

TNFα alters occludin and cerebral endothelial permeability: Role of p38MAPK

(2017) Yawen Ni et al.   PLoS One

The membrane attack complex as an inflammatory trigger

(2016) B. Paul Morgan   IMMUNOBIOLOGY

Islet-derived damage-associated molecular pattern molecule contributes to immune responses following microencapsulated neonatal porcine islet xenotransplantation in mice

(2016) Takeshi Itoh et al.   XENOTRANSPLANTATION

Initialin vitrostudies on tissues and cells from GTKO/CD46/NeuGcKO pigs

(2016) Whayoung Lee et al.   XENOTRANSPLANTATION

The role of genetically engineered pigs in xenotransplantation research

(2015) David KC Cooper et al.   JOURNAL OF PATHOLOGY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Pig kidney graft survival in a baboon for 136 days: longest life-supporting organ graft survival to date

(2015) Hayato Iwase et al.   XENOTRANSPLANTATION

Immunobiological barriers to xenotransplantation

(2015) David K.C. Cooper et al.   International Journal of Surgery

The need for xenotransplantation as a source of organs and cells for clinical transplantation

(2015) Burcin Ekser et al.   International Journal of Surgery

Complement and Its Receptors: New Insights into Human Disease

(2014) V. Michael Holers   Annual Review of Immunology

Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis

(2014) Xinyang Song et al.   IMMUNITY

Systemic inflammation in xenograft recipients precedes activation of coagulation

(2014) Mohamed B. Ezzelarab et al.   XENOTRANSPLANTATION

Interleukin-4 Induces Up-regulation of Endothelial Cell Claudin-5 through Activation of FoxO1

(2013) Agustin P. Dalmasso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAF6-Dependent Act1 Phosphorylation by the I B Kinase-Related Kinases Suppresses Interleukin-17-Induced NF- B Activation

(2012) F. Qu et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of complement in antibody-mediated rejection in kidney transplantation

(2012) Mark D. Stegall et al.   Nature Reviews Nephrology

Occludin Protein Family: Oxidative Stress and Reducing Conditions

(2011) Ingolf E. Blasig et al.   ANTIOXIDANTS & REDOX SIGNALING

Organ transplantation: historical perspective and current practice

(2011) C.J.E. Watson et al.   BRITISH JOURNAL OF ANAESTHESIA

Current Advances in Retroviral Gene Therapy

(2011) Youngsuk Yi et al.   CURRENT GENE THERAPY

The complement system

(2010) J. Vidya Sarma et al.   CELL AND TISSUE RESEARCH

TNF-  Signals Through PKC /NF- B to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

(2010) C. A. Aveleira et al.   DIABETES

Endothelial Function and Oxidative Stress in Cardiovascular Diseases

(2009) Yukihito Higashi et al.   CIRCULATION JOURNAL

Signaling pathway for TNF-α-induced MMP-9 expression: Mediation through p38 MAP kinase, and inhibition by anti-cancer molecule magnolol in human urinary bladder cancer 5637 cells

(2008) Se-Jung Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia

(2008) Wenlan Liu et al.   JOURNAL OF NEUROCHEMISTRY

In vitroinvestigation of pig cells for resistance to human antibody-mediated rejection

(2008) Hidetaka Hara et al.   TRANSPLANT INTERNATIONAL