Article
Chemistry, Applied
Xuan Zhang, Hongshan Liang, Jing Li, Bin Li
Summary: This study successfully fabricated processable and edible high internal phase Pickering emulsions (HIPPEs) and investigated their properties. The results showed that the properties of HIPPEs could be controlled by adjusting the concentration of GCCPs and centrifuging speed, and they exhibited good stability and processability.
FOOD HYDROCOLLOIDS
(2022)
Article
Nanoscience & Nanotechnology
Lu Tang, Jing Liao, Hongjie Dai, Yushan Liu, Huihua Huang
Summary: The study produced pineapple cellulose nanocrystals (PCNCs) from different sections of pineapple through sulfuric acid hydrolysis, and found variations in crystallinity and thermal stability among PCNCs from pineapple core, pulp, leaf, and peel, which also affected the stability of the Pickering emulsions.
Article
Chemistry, Physical
Parinaz Ataeian, Lucig Aroyan, Waleed Parwez, Kam C. Tam
Summary: This study investigated the capability of cellulose nanocrystals (CNCs) in stabilizing Pickering emulsions during temperature-induced phase transition. CNC-stabilized emulsions were found to be more stable than sodium dodecyl sulfate (SDS)-stabilized emulsions, and the droplet size was not affected by temperature variation. The findings contribute to a better understanding of the role of nanocrystals in emulsion stability.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Applied
Guangni Peng, Defeng Wu
Summary: This study investigates the differences in emulsifying properties between chitin nanocrystals (ChNCs) and cellulose nanocrystals (CNCs) in Pickering emulsions. ChNCs demonstrate higher emulsification capacity and can stabilize emulsions with high oil fractions, while CNCs show better stability to centrifugation at low oil fractions. The viscoelasticity and morphology/phase behavior of the two types of Pickering systems are correlated. This work provides valuable information for formulating Pickering emulsions using different types of rod-like polysaccharide nanocrystals.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Physical
Shengfeng Ye, Wenjing Zhang, Zhaolan Zhai, Binglei Song, Shibin Shang, Zhanqian Song
Summary: A CO2-responsive bio-based surfactant, C10MPAN', was successfully synthesized and used to prepare novel CO2-responsive Pickering gel emulsions with cellulose nanocrystals. The emulsions exhibited stable and controllable demulsification properties. The potential application of these emulsions was further validated through the study of microstructure, viscoelastic properties, and stability.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Applied
Hui Dong, Qijun Ding, Yifei Jiang, Xia Li, Wenjia Han
Summary: Spherical cellulose nanocrystals (S-CNCs) prepared by mixed acid hydrolysis under ultrasonic treatment are shown to be promising stabilizers for Pickering emulsions, exhibiting high stability and low viscosity.
CARBOHYDRATE POLYMERS
(2021)
Article
Agricultural Engineering
QiJie Chen, Na You, ChunYan Liang, YiNing Xu, Feng Wang, Bo Zhang, Peng Zhang
Summary: In this study, green composite films were prepared by incorporating ginger essential oil (GEO) Pickering emulsions stabilized by tempo-oxidized cellulose nanocrystals (TOCN) into a starch-based film-forming matrix. The results showed that the composite films exhibited improved antibacterial activity and tensile strength (TS). Moreover, the water vapor permeability of the films decreased by 60.3% and the TS increased by 25.0% when the amount of TOCN was 1.0 wt% and the GEO dosage was 22%.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Chemistry, Applied
Agata Sommer, Hanna Staroszczyk
Summary: This study compared the properties of disintegrated bacterial cellulose before and after freeze-drying, as well as its nanocrystals obtained using H2SO4 under different time and concentration conditions. The results showed that nanocrystals obtained with 30% acid had a similar structure to the parent cellulose, while nanocrystals obtained with 65% acid showed allomorphic transformation and cellulose sulfates formation. Nanocrystals obtained with 30% acid, as well as native bacterial cellulose, ensured the high stability of O/W emulsion containing up to 20% olive oil due to their strong surface charge density from negatively charged sulfate groups.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Applied
Ziang Guo, Zhihua Li, Shaoyi Cen, Nini Liang, Arslan Muhammad, Haroon Elrasheid Tahir, Jiyong Shi, Xiaowei Huang, Xiaobo Zou
Summary: This research looks at using polysaccharide complexes to stabilize Pickering emulsions for food 3D printing. The complexes consisting of beta-cyclodextrin and carboxymethyl cellulose form an interface membrane structure in the emulsion system. By adjusting the hydrophilicity of the complexes, the physical and chemical properties of the emulsion can be optimized for 3D printing. The stable Pickering emulsion showed excellent printing potential under the optimized conditions.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Physical
Veronika Mikulcova, Lucie Urbankova, Vera Kasparkova, Romain Bordes
Summary: Competitive adsorption of cellulose nanofibers at oil-water interface in Pickering emulsion is studied, and the effects of different types of nanocelluloses, particle concentrations, and oil content on the stability and droplet size of emulsions are investigated. Both cellulose nanocrystals (CNC) and cellulose nanofibrils (CNF) can stabilize emulsion droplets, with CNC producing smaller droplets and higher stability. The presence of CNF in the mixture reduces the ability of CNC particles to adsorb at the oil-water interface. The stability of emulsions is mainly influenced by oil content and total particle concentration.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Biochemistry & Molecular Biology
Shumin Wang, Yingxuan Xie, Huanhuan Su, Yanran Luo, Mengting Wang, Teng Li, Yuying Fu
Summary: Curcumin solid dispersions (Cur SDs) were prepared using hydroxypropyl methyl cellulose (HPMC) and sodium carboxymethyl cellulose (CMC) at different dosages. The addition of CMC enhanced the characteristic peak shift of curcumin, reduced contact angle, increased surface free energy, and improved the solubility of Cur SDs. The morphology of Cur SDs changed from needle-like to sheet-like with the addition of CMC. The addition of CMC significantly improved the anti-proliferation effect of Cur SDs, enhancing the bioavailability of curcumin.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Chunling Nie, Xianpan Bu, Sihong Ma, Jiahui Zhang, Qin Ma, Weilong Li, Xiaowan Zhang, Hao Wu, Shuqian Hu, Guangsen Fan, Jianguo Wang
Summary: This study investigated the stability of Pickering emulsions using cellulose nanocrystals (CNCs) and peanut protein isolate (PPI) complexes as emulsifier. The findings showed that Pickering emulsions stabilized by CNCs/PPI complexes exhibited better stability and oxidative stability compared to pure CNCs or PPI. These stable, edible, and surfactant-free Pickering emulsions have the potential for applications in oil-water separation and lipophilic nutrient delivery.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Applied
Hui Wang, Meng Zhang, Jinguang Hu, Haishun Du, Ting Xu, Chuanling Si
Summary: This study reports a highly efficient and sustainable approach to produce functionalized cellulose nanocrystals, which have excellent ability to stabilize oil-water and may serve as stabilizers for emulsions.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Yunwei Niu, Yuchen Gao, Zuobing Xiao, Chengting Mao, Huiting Wang, Yijia Geng, Yuanqing Ye, Xingran Kou
Summary: This study investigates the effects of cellulose nanocrystals on the stability of starch-based Pickering emulsions. The results show that the stability of Pickering emulsions is significantly improved by adding cellulose nanocrystals. Cellulose nanocrystals increase the viscosity, electrostatic repulsion, and steric hindrance of the emulsions, which delays the movement of droplets and obstructs the contact between droplets. This study provides new insights into the preparation and stabilization of starch-based Pickering emulsions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Shaoning Cui, Congli Cui, Shengju Ge, Wei Xie, Mengting Yu, Ying Li, Qingjie Sun, Liu Xiong
Summary: The physical properties of hydrocolloids currently restrict their wide application in the food industry. By adding cellulose nanocrystals (CNCs) to sodium carboxymethyl cellulose (CMC) and sodium alginate (SA) solutions, their viscoelasticity can be improved and the non-Newtonian flow behaviors can be regulated under different conditions.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Pharmacology & Pharmacy
Ruoning Wang, Jiawei Han, Ai Jiang, Rong Huang, Tingming Fu, Lingchong Wang, Qin Zheng, Wen Li, Junsong Li
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2019)
Article
Chemistry, Medicinal
Jiaojiao Jiao, Yuanzhen Yang, Zhenfeng Wu, Bingtao Li, Qin Zheng, Shaofeng Wei, Yaqi Wang, Ming Yang
Article
Integrative & Complementary Medicine
Yu Zhong, Qin Zheng, Pengyi Hu, Xiaoying Huang, Ming Yang, Guilin Ren, Qing Du, Jun Luo, Kenan Zhang, Jing Li, Haixia Wu, Yuanyuan Guo, Shanshan Liu
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2019)
Article
Pharmacology & Pharmacy
Yijing Luo, Yang Liu, Yingchong Chen, Shuyuan Shuai, Qin Zheng, Ming Yang, Pengfei Yue
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2020)
Article
Chemistry, Applied
Yijing Luo, Zengzhu Zhang, Guiting Huang, Huaping Yu, Yueqin Ma, Qin Zheng, Pengfei Yue
CARBOHYDRATE POLYMERS
(2020)
Article
Pharmacology & Pharmacy
Guiting Huang, Jin Xie, Shuyuan Shuai, Shaofeng Wei, Yingchong Chen, Zhiyu Guan, Qin Zheng, Pengfei Yue, Changhong Wang
Summary: This study successfully utilized a carbohydrate polymer deacetylated gellan gum (DGG) as matrix to design nanocrystals-based intranasal in situ gel (IG) for nose-to-brain drug delivery, showing excellent therapeutic efficacy.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Review
Food Science & Technology
Abid Naeem, Yang Ming, Hu Pengyi, Kang Yong Jie, Liu Yali, Haiyan Zhang, Xiao Shuai, Wenjing Li, Wu Ling, Zhang Ming Xia, Liu Shan Shan, Zheng Qin
Summary: Despite advances in synthetic chemistry, nature remains the primary source of drug discovery. Flavonoids have shown significant therapeutic activities, yet they face absorption disorders leading to low bioavailability. Further investigation is needed to understand these interactions and enhance their effectiveness in clinical applications.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Food Science & Technology
Fen Yu, Na Wan, Qin Zheng, Yuanhui Li, Ming Yang, Zhenfeng Wu
Summary: The study revealed that ultrasound pretreatment and microwave pretreatment can reduce extraction time, increase yield, and enhance DPPH radical-scavenging activity of kumquat peel essential oil. Compared to microwave pretreatment, ultrasound pretreatment showed higher essential oil yield and antioxidant activity.
FOOD SCIENCE & NUTRITION
(2021)
Article
Nutrition & Dietetics
Zheng Qin, Qinbo Yang, Ruoxi Liao, Baihai Su
Summary: The study found a positive association between dietary inflammation index and parathyroid hormone levels, as well as an increased risk of hyperparathyroidism. Anti-inflammatory dietary management may be beneficial in reducing the risk of hyperparathyroidism in both CKD and non-CKD populations.
FRONTIERS IN NUTRITION
(2021)
Article
Plant Sciences
Yu Zhong, Qin Zheng, Pengyi Hu, Xiaoying Huang, Ming Yang, Guilin Ren, Jing Li, Qing Du, Shanshan Liu, Kenan Zhang, Ling Wu, Liyun Zhu, Yuanyuan Guo, Wenjing Li, Shuai Xiao, Shuyuan Shuai, Mingxia Zhang
Summary: The inhalation of Perilla frutescens essential oil (PFEO) has sedative and hypnotic effects by reducing autonomic activity, increasing falling asleep rate, shortening latency of sleeping time, and prolonging duration of sleeping time. PFEO increases the content of 5-HT and GABA in the hypothalamus and cerebral cortex, and may exert its sedative and hypnotic effects through the GABAergic pathway.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Food Science & Technology
Na Wan, Hao Xie, Fen Yu, Yuanhui Li, Qin Zheng, Zhenfeng Wu
Summary: Ultrasound-assisted vacuum extraction was applied to improve the efficiency and quality of Kumquat peel essential oil. Results showed that ultrasound-assisted vacuum extraction allowed higher essential oil yield and antioxidant activity, and reduced extraction time compared to traditional methods.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Article
Nutrition & Dietetics
Jiwen Geng, Yuxuan Qiu, Yupei Li, Jiameng Li, Ruoxi Liao, Heyue Du, Luojia Jiang, Liya Wang, Zheng Qin, Qinbo Yang, Qiao Yu, Zhuyun Zhang, Baihai Su
Summary: This study examined the associations between 25(OH)D and kidney function, as well as the associations between both of them and insulin resistance (IR). The results showed that serum 25-hydroxyvitamin D concentrations were negatively associated with kidney function, and IR was present in the early stage of kidney dysfunction.
FRONTIERS IN NUTRITION
(2022)
Article
Integrative & Complementary Medicine
Le-Min Xia, Ai-Ping Zhang, Qin Zheng, Jie Ding, Zhe Jin, Hai Yu, Wan-Hui Wong, He-Ping Yu
Summary: This study reveals that Quercetin-3-O-beta-D-glucuronide (QG) inhibits mitochondrial pathway-mediated platelet apoptosis through the PI3K/AKT pathway, thereby increasing platelet counts in immunological bone marrow failure (BMF). This finding sheds light on exploring the possible regulatory mechanism of traditional Chinese medicine in the treatment of thrombocytopenia induced by BMF.
WORLD JOURNAL OF TRADITIONAL CHINESE MEDICINE
(2022)
Article
Medical Laboratory Technology
Wei Liu, Qin Zheng, Qiong Yu, Xiaoyun Wang, Ying Zhou
Summary: The study explored the effects of isovolumic hemodilution and platelet-rich plasma separation on platelet activation state and function, complications, and inflammation in patients undergoing cardiac surgery. It was found that platelet-rich plasma separation technology effectively maintained platelet function, reduced blood viscosity, ensured stable coagulation function, increased hemoglobin levels, and decreased inflammatory reactions in patients undergoing cardiac surgery under extracorporeal circulation. Additionally, this approach resulted in fewer adverse reactions and facilitated postoperative recovery.
CLINICAL LABORATORY
(2021)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
