ERK/Nrf2 pathway activation by caffeic acid in HepG2 cells alleviates its hepatocellular damage caused by t-butylhydroperoxide-induced oxidative stress
出版年份 2019 全文链接
标题
ERK/Nrf2 pathway activation by caffeic acid in HepG2 cells alleviates its hepatocellular damage caused by t-butylhydroperoxide-induced oxidative stress
作者
关键词
Caffeic acid, <em class="EmphasisTypeItalic ">tert</em>-butyl hydroperoxide, Glutamate-cysteine ligase, ERK/Nrf2 pathway, Antioxidant response element
出版物
BMC Complementary and Alternative Medicine
Volume 19, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-06-20
DOI
10.1186/s12906-019-2551-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Possible involvement of transcriptional activation of nuclear factor erythroid 2-related factor 2 (Nrf2) in the protective effect of caffeic acid on paraquat-induced oxidative damage in Drosophila melanogaster
- (2019) Ricardo Gomes dos Santos Nunes et al. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
- Caffeic acid prevents acetaminophen-induced liver injury by activating the Keap1-Nrf2 antioxidative defense system
- (2016) Chun Pang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Caffeic acid induces glutathione synthesis through JNK/AP-1-mediated γ-glutamylcysteine ligase catalytic subunit induction in HepG2 and primary hepatocytes
- (2015) Sung-Yong Yang et al. FOOD SCIENCE AND BIOTECHNOLOGY
- Perilla frutescens modulates CYP1A1/2 and HO-1 and activates Nrf2 in oxidative stress-induced hepatotoxicity
- (2015) Jeong Han Kang et al. Journal of the Korean Society for Applied Biological Chemistry
- Lico A Enhances Nrf2-Mediated Defense Mechanisms againstt-BHP-Induced Oxidative Stress and Cell Death via Akt and ERK Activation in RAW 264.7 Cells
- (2015) Hongming Lv et al. Oxidative Medicine and Cellular Longevity
- The hepatoprotection of caffeic acid and rosmarinic acid, major compounds of Perilla frutescens, against t-BHP-induced oxidative liver damage
- (2013) Sung-Yong Yang et al. FOOD AND CHEMICAL TOXICOLOGY
- Role of the Nrf2-ARE Pathway in Liver Diseases
- (2013) Sang Mi Shin et al. Oxidative Medicine and Cellular Longevity
- Protection by chrysin, apigenin, and luteolin against oxidative stress is mediated by the Nrf2-dependent up-regulation of heme oxygenase 1 and glutamate cysteine ligase in rat primary hepatocytes
- (2012) Chin-Shiu Huang et al. ARCHIVES OF TOXICOLOGY
- Protective effect of extracts of Perilla frutescens treated with sucrose on tert-butyl hydroperoxide-induced oxidative hepatotoxicity in vitro and in vivo
- (2012) Sung-Yong Yang et al. FOOD CHEMISTRY
- Caffeic Acid, A Versatile Pharmacophore: An Overview
- (2012) M. Touaibia et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress
- (2011) Ya-Chen Yang et al. FREE RADICAL BIOLOGY AND MEDICINE
- PI3K and ERK/Nrf2 pathways are involved in oleanolic acid-induced heme oxygenase-1 expression in rat vascular smooth muscle cells
- (2011) Jian Feng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Isolation of caffeic acid from Perilla frutescens and its role in enhancing γ-glutamylcysteine synthetase activity and glutathione level
- (2009) Ho-Young Park et al. FOOD CHEMISTRY
- Efficacy of caffeic acid in preventing nickel induced oxidative damage in liver of rats
- (2008) L. Pari et al. CHEMICO-BIOLOGICAL INTERACTIONS
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