MiR-7-5p-mediated downregulation of PARP1 impacts DNA homologous recombination repair and resistance to doxorubicin in small cell lung cancer

MiR-7-5p functions as a tumor suppressor by targeting SOX18 in pancreatic ductal adenocarcinoma

(2018) Weihua Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

miR-7-5p overexpression suppresses cell proliferation and promotes apoptosis through inhibiting the ability of DNA damage repair of PARP-1 and BRCA1 in TK6 cells exposed to hydroquinone

(2018) Hao Luo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

MiR-7-5p suppresses stemness and enhances temozolomide sensitivity of drug-resistant glioblastoma cells by targeting Yin Yang 1

(2018) Bo Jia et al.   EXPERIMENTAL CELL RESEARCH

AN-7, a butyric acid prodrug, sensitizes cutaneous T-cell lymphoma cell lines to doxorubicin via inhibition of DNA double strand breaks repair

(2017) Lilach Moyal et al.   INVESTIGATIONAL NEW DRUGS

The multifaceted roles of PARP1 in DNA repair and chromatin remodelling

(2017) Arnab Ray Chaudhuri et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Let-7e sensitizes epithelial ovarian cancer to cisplatin through repressing DNA double strand break repair

(2017) Man Xiao et al.   Journal of Ovarian Research

DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme

(2016) Zachary D. Nagel et al.   CANCER RESEARCH

Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress

(2016) Yao Zhang et al.   Oncotarget

miR-7 modulates chemoresistance of small cell lung cancer by repressing MRP1/ABCC1

(2015) Huanxin Liu et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Upregulation of the inwardly rectifying potassium channel Kir2.1 (KCNJ2) modulates multidrug resistance of small-cell lung cancer under the regulation of miR-7 and the Ras/MAPK pathway

(2015) Huanxin Liu et al.   Molecular Cancer

Readers of poly(ADP-ribose): designed to be fit for purpose

(2015) Federico Teloni et al.   NUCLEIC ACIDS RESEARCH

CD133+ Cancer Stem-like Cells in Small Cell Lung Cancer Are Highly Tumorigenic and Chemoresistant but Sensitive to a Novel Neuropeptide Antagonist

(2014) S. Sarvi et al.   CANCER RESEARCH

Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair

(2014) A. Mehta et al.   Cold Spring Harbor Perspectives in Biology

PARP1-Driven Poly-ADP-Ribosylation Regulates BRCA1 Function in Homologous Recombination-Mediated DNA Repair

(2014) Y. Hu et al.   Cancer Discovery

Function of BRCA1 in the DNA Damage Response Is Mediated by ADP-Ribosylation

(2013) Mo Li et al.   CANCER CELL

Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining

(2013) Angela Helfricht et al.   CELL CYCLE

MicroRNA and signal transduction pathways in tumor radiation response

(2013) Luqing Zhao et al.   CELLULAR SIGNALLING

DNA-Damaging Agents in Cancer Chemotherapy: Serendipity and Chemical Biology

(2013) Kahlin Cheung-Ong et al.   CHEMISTRY & BIOLOGY

miR-9 Regulation of BRCA1 and Ovarian Cancer Sensitivity to Cisplatin and PARP Inhibition

(2013) Chaoyang Sun et al.   JNCI-Journal of the National Cancer Institute

miRNA-7-5p inhibits melanoma cell migration and invasion

(2012) Keith M. Giles et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Small-cell lung cancer

(2011) Jan P van Meerbeeck et al.   LANCET

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors

(2010) Patryk Moskwa et al.   MOLECULAR CELL

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNAs: new players in the DNA damage response

(2010) H. Hu et al.   Journal of Molecular Cell Biology

Analysis of DNA Double-strand Break (DSB) Repair in Mammalian Cells

(2010) Andrei Seluanov et al.   Jove-Journal of Visualized Experiments

Regulation of Epidermal Growth Factor Receptor Signaling in Human Cancer Cells by MicroRNA-7

(2008) Rebecca J. Webster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY