The Mycobacterium tuberculosis capsule: a cell structure with key implications in pathogenesis

Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid ofMycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen

(2018) Alok Choudhary et al.   JOURNAL OF IMMUNOLOGY

A novel sensitive immunoassay targeting the MTX-Lipoarabinomannan epitope meets the WHO's performance target for Tuberculosis diagnosis

(2018) George B. Sigal et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Latently and uninfected healthcare workers exposed to TB make protective antibodies againstMycobacterium tuberculosis

(2017) Hao Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS

(2017) David Albesa-Jové et al.   STRUCTURE

Integrating Lung Physiology, Immunology, and Tuberculosis

(2017) Jordi B. Torrelles et al.   TRENDS IN MICROBIOLOGY

M. tuberculosis -Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1

(2017) Murugesan V.S. Rajaram et al.   Cell Reports

Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine

(2017) Rafael Prados-Rosales et al.   PLoS Pathogens

Abundance and co-occurrence of extracellular capsules increase environmental breadth: Implications for the emergence of pathogens

(2017) Olaya Rendueles et al.   PLoS Pathogens

Assembly of α-Glucan by GlgE and GlgB in Mycobacteria and Streptomycetes

(2016) Abdul M. Rashid et al.   BIOCHEMISTRY

Driving the Way to Tuberculosis Elimination: The Essential Role of Fundamental Research

(2016) Christian Lienhardt et al.   CLINICAL INFECTIOUS DISEASES

The conformational plasticity of glycosyltransferases

(2016) David Albesa-Jové et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection

(2016) Kenji Toyonaga et al.   IMMUNITY

Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria

(2016) Robert van de Weerd et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Type of Growth Medium Affects the Presence of a Mycobacterial Capsule and Is Associated With Differences in Protective Efficacy of BCG Vaccination AgainstMycobacterium tuberculosis

(2016) Rafael Prados-Rosales et al.   JOURNAL OF INFECTIOUS DISEASES

Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction

(2016) Tingting Chen et al.   JOURNAL OF INFECTIOUS DISEASES

Structural Basis of Glycogen Biosynthesis Regulation in Bacteria

(2016) Javier O. Cifuente et al.   STRUCTURE

Lipoarabinomannan, and its related glycolipids, induce divergent and opposing immune responses to Mycobacterium tuberculosis depending on structural diversity and experimental variations

(2016) Gunilla Källenius et al.   TUBERCULOSIS

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10

(2016) Louis S. Ates et al.   PLoS Pathogens

Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis

(2016) Hendrik Koliwer-Brandl et al.   PLoS Pathogens

Assembly of the Mycobacterial Cell Wall

(2015) Monika Jankute et al.   Annual Review of Microbiology

Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium tuberculosis

(2015) Matías D. Asención Diez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Release of mycobacterial antigens

(2015) Laleh Majlessi et al.   IMMUNOLOGICAL REVIEWS

Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi

(2015) Lisa Brown et al.   NATURE REVIEWS MICROBIOLOGY

Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

(2015) Ana Maranha et al.   Scientific Reports

Enzymatic modifications of exopolysaccharides enhance bacterial persistence

(2015) Gregory B. Whitfield et al.   Frontiers in Microbiology

Z-100, an Immunomodulatory Extract of Mycobacterium tuberculosis Strain Aoyama B, Prevents Spontaneous Lymphatic Metastasis of B16-BL6 Melanoma

(2014) Takayuki Horii et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The cell envelope glycoconjugates ofMycobacterium tuberculosis

(2014) Shiva Kumar Angala et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria

(2014) Akiko Yonekawa et al.   IMMUNITY

Mutations in the Essential Arabinosyltransferase EmbC Lead to Alterations inMycobacterium tuberculosisLipoarabinomannan

(2014) Aaron Korkegian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LprG-Mediated Surface Expression of Lipoarabinomannan Is Essential for Virulence of Mycobacterium tuberculosis

(2014) Rajiv L. Gaur et al.   PLoS Pathogens

Mycobacterium tuberculosis Lipoprotein LprG Binds Lipoarabinomannan and Determines Its Cell Envelope Localization to Control Phagolysosomal Fusion

(2014) Supriya Shukla et al.   PLoS Pathogens

ESX-1-induced apoptosis is involved in cell-to-cell spread ofMycobacterium tuberculosis

(2013) J. I. Aguilo et al.   CELLULAR MICROBIOLOGY

Changes in the major cell envelope components of Mycobacterium tuberculosis during in vitro growth

(2013) Lanhao Yang et al.   GLYCOBIOLOGY

Mycobacterium tuberculosisMaltosyltransferase GlgE, a Genetically Validated Antituberculosis Target, Is Negatively Regulated by Ser/Thr Phosphorylation

(2013) Jade Leiba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

(2013) C. J. Cambier et al.   NATURE

Divergent Effects of Mycobacterial Cell Wall Glycolipids on Maturation and Function of Human Monocyte-Derived Dendritic Cells

(2012) Jolanta Mazurek et al.   PLoS One

Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice

(2011) Rafael Prados-Rosales et al.   JOURNAL OF CLINICAL INVESTIGATION

Mycobacterium tuberculosis lipoarabinomannan enhances LPS-induced TNF-α production and inhibits NO secretion by engaging scavenger receptors

(2011) Szczepan Józefowski et al.   MICROBIAL PATHOGENESIS

In vitro culture medium influences the vaccine efficacy of Mycobacterium bovis BCG

(2011) Manjunatha M. Venkataswamy et al.   VACCINE

Escherichia coliglycogen genes are organized in a singleglgBXCAPtranscriptional unit possessing an alternative suboperonic promoter withinglgCthat directsglgAPexpression

(2010) Manuel Montero et al.   BIOCHEMICAL JOURNAL

Mycobacterium tuberculosis employs Cpn60.2 as an adhesin that binds CD43 on the macrophage surface

(2010) Tyler B. M. Hickey et al.   CELLULAR MICROBIOLOGY

Molecular Basis of Phosphatidyl-myo-inositol Mannoside Biosynthesis and Regulation in Mycobacteria

(2010) Marcelo E. Guerin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ABC Transporters Involved in Export of Cell Surface Glycoconjugates

(2010) L. Cuthbertson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an α-glucan pathway

(2010) Rainer Kalscheuer et al.   Nature Chemical Biology

Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors

(2010) Clifford V. Harding et al.   NATURE REVIEWS MICROBIOLOGY

Optimisation of Bioluminescent Reporters for Use with Mycobacteria

(2010) Nuria Andreu et al.   PLoS One

A truncated lipoglycan from mycobacteria with altered immunological properties

(2010) H. L. Birch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting

(2010) N. Joller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins

(2010) Musa Sani et al.   PLoS Pathogens

DC-SIGN and mannosylated surface structures of Mycobacterium tuberculosis: a deceptive liaison

(2009) Stefan Ehlers   EUROPEAN JOURNAL OF CELL BIOLOGY

Mycobacterium tuberculosis Cpn60.2 and DnaK Are Located on the Bacterial Surface, Where Cpn60.2 Facilitates Efficient Bacterial Association with Macrophages

(2009) T. B. M. Hickey et al.   INFECTION AND IMMUNITY

Coordinate Regulation of Glycan Degradation and Polysaccharide Capsule Biosynthesis by a Prominent Human Gut Symbiont

(2009) Eric C. Martens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A murine DC-SIGN homologue contributes to early host defense againstMycobacterium tuberculosis

(2009) Antoine Tanne et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of Mycobacterial  -Glucan As a Novel Ligand for DC-SIGN: Involvement of Mycobacterial Capsular Polysaccharides in Host Immune Modulation

(2009) J. Geurtsen et al.   JOURNAL OF IMMUNOLOGY

Preliminary crystallographic analysis of GpgS, a key glucosyltransferase involved in methylglucose lipopolysaccharide biosynthesis inMycobacterium tuberculosis

(2008) Petra Gest et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Role of C-Type Lectins in Mycobacterial Infections

(2008) L. Schlesinger et al.   CURRENT DRUG TARGETS

Comparative structural analyses of the  -glucan and glycogen from Mycobacterium bovis

(2008) P. Dinadayala et al.   GLYCOBIOLOGY

Direct Visualization of the Outer Membrane of Mycobacteria and Corynebacteria in Their Native State

(2008) B. Zuber et al.   JOURNAL OF BACTERIOLOGY

Identification ofMycobacterium tuberculosisClinical Isolates with Altered Phagocytosis by Human Macrophages Due to a Truncated Lipoarabinomannan

(2008) Jordi B. Torrelles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Capsular glucan and intracellular glycogen ofMycobacterium tuberculosis: biosynthesis and impact on the persistence in mice

(2008) Tounkang Sambou et al.   MOLECULAR MICROBIOLOGY

Disclosure of the mycobacterial outer membrane: Cryo-electron tomography and vitreous sections reveal the lipid bilayer structure

(2008) C. Hoffmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of TNF-α-induced Cyclooxygenase-2 Expression byMycobacterium bovisBCG in Human Alveolar Epithelial A549 Cells

(2008) K. Bansal et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The immunomodulatory lipoglycans, lipoarabinomannan and lipomannan, are exposed at the mycobacterial cell surface

(2008) Sylvain Pitarque et al.   TUBERCULOSIS