Single-Cell RNA-Sequencing and Metabolomics Analyses Reveal the Contribution of Perivascular Adipose Tissue Stem Cells to Vascular Remodeling

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

(2019) David Merrick et al.   SCIENCE

Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing

(2019) Wenduo Gu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of Resident Stem Cells in Vessel Formation and Arteriosclerosis

(2018) Li Zhang et al.   CIRCULATION RESEARCH

Smooth muscle cells differentiated from mesenchymal stem cells are regulated by microRNAs and suitable for vascular tissue grafts

(2018) Wenduo Gu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

A stromal cell population that inhibits adipogenesis in mammalian fat depots

(2018) Petra C. Schwalie et al.   NATURE

RUNX1 Plays an Important Role in Mediating BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells Line C3H10T1/2, Murine Multi-Lineage Cells Lines C2C12 and MEFs

(2017) Caixia Ji et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CD34+mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury

(2017) Igor Stzepourginski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Networks in Single Perivascular Cells Sorted from Human Adipose Tissue Reveal a Hierarchy of Mesenchymal Stem Cells

(2017) W. Reef Hardy et al.   STEM CELLS

Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation

(2017) Emily L. Goldberg et al.   Molecular Metabolism

Adipose-derived stromal cell in regenerative medicine: A review

(2017) Reza Tabatabaei Qomi et al.   World Journal of Stem Cells

Adventitial Sca1+ Cells Transduced With ETV2 Are Committed to the Endothelial Fate and Improve Vascular Remodeling After Injury

(2017) Alexandra Le Bras et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Perivascular adipose tissue as a regulator of vascular disease pathogenesis: identifying novel therapeutic targets

(2016) Ioannis Akoumianakis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State

(2016) Wen Gu et al.   Cell Stem Cell

Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing

(2016) Navdeep S. Chandel et al.   NATURE CELL BIOLOGY

Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown

(2016) Mihaela Pertea et al.   Nature Protocols

Brown adipose tissue as a secretory organ

(2016) Francesc Villarroya et al.   Nature Reviews Endocrinology

Metabolic profiling of hematopoietic stem and progenitor cells during proliferation and differentiation into red blood cells

(2016) Hasbullah Daud et al.   New Biotechnology

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

(2015) Nicola K. Wilson et al.   Cell Stem Cell

Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells

(2015) Florian Buettner et al.   NATURE BIOTECHNOLOGY

MetaboAnalyst 3.0—making metabolomics more meaningful

(2015) Jianguo Xia et al.   NUCLEIC ACIDS RESEARCH

The Role of miR-378a in Metabolism, Angiogenesis, and Muscle Biology

(2015) Bart Krist et al.   International Journal of Endocrinology

Transplanted Perivascular Adipose Tissue Accelerates Injury-Induced Neointimal Hyperplasia

(2014) David Manka et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proinflammatory Phenotype of Perivascular Adipocytes

(2014) Abdullah Omar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications

(2014) Ying Wang et al.   NATURE IMMUNOLOGY

Adventitial Stem Cells in Vein Grafts Display Multilineage Potential That Contributes to Neointimal Formation

(2013) Yikuan Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitochondrial Regulation in Pluripotent Stem Cells

(2013) Xiuling Xu et al.   Cell Metabolism

Loss of Perivascular Adipose Tissue on Peroxisome Proliferator–Activated Receptor-γ Deletion in Smooth Muscle Cells Impairs Intravascular Thermoregulation and Enhances Atherosclerosis

(2012) Lin Chang et al.   CIRCULATION

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

(2012) Keisuke Ito et al.   NATURE MEDICINE

Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α

(2012) Diarmaid D Houlihan et al.   Nature Protocols

Metabolite profiling of recombinant CHO cells: Designing tailored feeding regimes that enhance recombinant antibody production

(2011) Christopher A. Sellick et al.   BIOTECHNOLOGY AND BIOENGINEERING

The Origins of Mesenchymal Stromal Cell Heterogeneity

(2011) Meirav Pevsner-Fischer et al.   Stem Cell Reviews and Reports

Tissue-Resident Adult Stem Cell Populations of Rapidly Self-Renewing Organs

(2010) Nick Barker et al.   Cell Stem Cell

Crosstalk between perivascular adipose tissue and blood vessels

(2010) Srinivas Rajsheker et al.   CURRENT OPINION IN PHARMACOLOGY

Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos

(2010) Slobodan Beronja et al.   NATURE MEDICINE

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

Defining Stem and Progenitor Cells within Adipose Tissue

(2008) Guiting Lin et al.   STEM CELLS AND DEVELOPMENT