Review
Chemistry, Inorganic & Nuclear
Xi Yang, Di Yuan, Jinhong Hou, Adam C. Sedgwick, Suying Xu, Tony D. James, Leyu Wang
Summary: The field of supramolecular chemistry has rapidly expanded and become highly influential in various areas like biomedicine, energy materials, catalysis, and sensing. The combination of host/guest chemistry with functional inorganic nanoparticles has led to many new applications in drug delivery, bioimaging, and sensing. Recent progress in the development of organic/inorganic supramolecular nano-systems incorporating host/guest chemistry has been summarized, highlighting their applications in drug delivery, biological imaging, and sensing.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Hugh P. Ryan, Cally J. E. Haynes, Alyssa Smith, Angela B. Grommet, Jonathan R. Nitschke
Summary: A method for immobilizing coordination cages on alumina has been reported, allowing for the encapsulation and separation of guest and non-guest molecules. Quantification of cage loadings and guest displacement assays demonstrate the retained ability of the adsorbed cages.
ADVANCED MATERIALS
(2021)
Editorial Material
Chemistry, Multidisciplinary
Paulina Hernandez-Pacheco, Gustavo A. Zelada-Guillen, Margarita Romero-Avila, Roberto Carlos Canas-Alonso, Marcos Flores-Alamo, Martha V. Escarcega-Bobadilla
Summary: We synthesized and characterized a new Cu-Salphen compound, which acted as a Lewis acid to host guest anions in two different forms: a) free molecule, and b) copolymerized with protective co-monomers. Higher amounts of Cu-Salphen resulted in larger and more homogeneous polymer sizes. The polymer size, along with other factors such as glass transitions, heat capacity, thermal degradation, and host-guest species distribution, explained significant enhancements in the host's binding site.
Article
Chemistry, Multidisciplinary
Paulina Hernandez-Pacheco, Gustavo A. Zelada-Guillen, Margarita Romero-Avila, Roberto Carlos Canas-Alonso, Marcos Flores-Alamo, Martha Escarcega-Bobadilla
Summary: In this study, the synthesis and crystallographic characterization of a new Cu-Salphen compound and its use as a Lewis acid against guest anions were described. It was found that higher contents of Cu-Salphen resulted in larger and more homogeneous polymer sizes. The growth of the host's binding site was explained by factors such as polymer size, glass transitions, heat capacity, thermal degradation, guest-saturation degrees, and host-guest species distribution profiles. Spectrofluorimetry measurements showed that Cu-Salphen had larger blue-shifted luminescence in the polymers compared to the non-polymerized counterpart, and enhanced fluorescence upon guest association. A cooperative incorporation of the guests into the internally protected binding site pockets in the random coil polymer conformations was proposed.
Article
Polymer Science
Amy C. Madl, David Myung
Summary: Over 6.2 million people worldwide suffer from moderate to severe vision loss due to corneal disease. While transplantation with allogenic donor tissue is sight-restoring for many patients with corneal blindness, this treatment modality is limited by long waiting lists and high rejection rates. Host-guest interactions have emerged as an important crosslinking strategy for cytocompatible, minimally invasive, injectable tissue substitutes.
Article
Chemistry, Multidisciplinary
Alejandro Lopez-Moreno, Susana Ibanez, Sara Moreno-Da Silva, Luisa Ruiz-Gonzalez, Natalia Martin Sabanes, Eduardo Peris, Emilio M. Perez
Summary: Mechanically interlocked derivatives of carbon nanotubes (MINTs) are interesting and stable nanotube products. This study explores the encapsulation of single-walled carbon nanotubes within a palladium-based metallosquare, revealing the sensitivity of MINT formation to structural variations of the metallo-assemblies. The study also demonstrates the potential application expansion of MINTs through supramolecular coordination complexes.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Roelof Steeno, Andrea Minoia, Roberto Lazzaroni, Kunal S. Mali, Steven De Feyter
Summary: Nanoscopic lateral confinement on a graphite surface allows for the study of embryonic stages of molecular self-assembly on solid surfaces using scanning tunneling microscopy at the solution/solid interface.
CHEMICAL COMMUNICATIONS
(2022)
Review
Chemistry, Inorganic & Nuclear
Shunsuke Ohtani, Kenichi Kato, Shixin Fa, Tomoki Ogoshi
Summary: Pillar[n]arenes, a new type of pillar-shaped host molecule, exhibit versatile and unique host-guest behaviors in host-guest chemistry. Solid-state host-guest complexation offers advantages such as cavity-size dependency, efficient complexation, and easy isolation and reuse. This review discusses recent developments in solid-state host-guest complexation using crystalline pillar[n]arenes, networks containing pillar[n]arenes, pillar[n]arene-assembled surfaces, and solid-state organic polymers.
COORDINATION CHEMISTRY REVIEWS
(2022)
Review
Agriculture, Multidisciplinary
Wenjie Li, Weiwei Xu, Siyun Zhang, Jia Li, Juan Zhou, Demei Tian, Jing Cheng, Haibing Li
Summary: Significant progress has been made in the research on drug encapsulation and release based on supramolecular macrocycles, laying a solid foundation for the development of novel nanopesticide preparations.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Xiaoqin Cui, Fu-Qiang Zhang, Xin Li, Juan-Juan Hou, Huan Li, Xian-Ming Zhang
Summary: The research describes a new type of inorganic host material, titanium-oxide or polyoxotitanate clusters, which can encapsulate inorganic molecules or ions. A specific molecular cage, Ti-18, was found to encapsulate an entire organic ethylenediamine ion and demonstrate exceptional versatility in balancing charges and facilitating reactions. Ti-18 exhibits strong light absorption due to ethylenediamine coordination and shows superior photocatalytic activity compared to anatase TiO2.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Guotai Li, Fanny Trausel, Michelle P. van Der Helm, Benjamin Klemm, Tobias G. Breve, Susan A. P. van Rossum, Muhamad Hartono, Harm H. P. J. Gerlings, Matija Lovrak, Jan H. van Esch, Rienk Eelkema
Summary: The study explores the use of cucurbit[7]uril molecular container to modulate the activity of synthetic organocatalysts, successfully changing the activity of four different organocatalysts and one initiator, with the potential to regulate chemical reaction rates.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Mingyang Zhang, Hao Zhang, Lunqiang Jin, Hao Li, Simin Liu, Shuai Chang, Feng Liang
Summary: Enhanced guest-pair interactions in the CB[8] cavity were quantitatively determined using SMFS, showing how dynamic conformational changes can affect the rupture force of CB[8]-mediated heteroternary complexation. SMFS was also utilized for detecting methyl viologen based on competitive host-guest interactions in CB[8] or CB[7.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Natsumi Nitta, Shin-ichi Kihara, Takeharu Haino
Summary: We developed a new synthetic method to construct supramolecular A(8)B(n) (n=1, 2, 4) miktoarm star copolymers through host-guest complexation. The formation of these copolymers was confirmed by various analytical techniques. The miktoarm copolymers exhibited phase separation in bulk, and the micro-Brownian motion of the A(8)B(4) structure was enhanced due to weak segregation interaction between immiscible arms.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Physical
Jaemin Kim, Jewon Choi, Kiho Park, Sungchan Kim, Kwan Woo Nam, Kookheon Char, Jang Wook Choi
Summary: Increasing the silicon content in the silicon-graphite composite anode to maximize the energy density of a lithium-ion battery cell is a challenging task due to the contradictory surface characteristics of silicon and graphite. This study presents an amphiphilic host-guest complex binder composed of pyrene-conjugated poly(acrylic acid) and a hyperbranched gamma-cyclodextrin polymer, which effectively maintains the integrity of the electrode and improves the cycling performance and rate capability of Si-Gr electrodes.
ADVANCED ENERGY MATERIALS
(2022)
Article
Polymer Science
Hui Guo, Gaelle Le Fer, Thi Nga Tran, Aurelie Malfait, Dominique Hourdet, Alba Marcellan, Francois Stoffelbach, Joel Lyskawa, Richard Hoogenboom, Patrice Woisel
Summary: The combination of thermo-responsive polymers with supramolecular chemistry has led to the development of adaptive materials based on reversible regulation of host-guest complexation. The study found that the phase separation mechanism of thermoresponsive polymers is a key factor that dominates the host-guest complexation behavior.
Article
Chemistry, Inorganic & Nuclear
Seulgi Kim, In-Hyeok Park, Huiyeong Ju, Yelim Lee, Joon Rae Kim, Jong Hwa Jung, Shim Sung Lee, Eunji Lee
Summary: In the field of supramolecules, the fabrication of polyrotaxanes or poly-pseudo-rotaxanes remains a challenge. This study reports the formation of a poly-pseudo-rotaxane in which a single salt-type guest acts as both a linking and a threading agent. The use of A1/A2-thiopyridyl pillar[5]arene (L) and silver(I) trifluoroacetate in CHCl3/CH3OH produced a one-dimensional (1D) poly-pseudo-rotaxane. Surprisingly, the AgCF3CO2 guest not only linked the di-armed L ligands but also threaded into the pillar[5]arene cavity. However, a simple 1D coordination polymer was obtained in a different solvent due to the presence of a CH2Cl2 molecule in the pillar[5]arene cavity.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Seulgi Kim, Jihye Oh, Ki-Min Park, Shim Sung Lee, In-Hyeok Park
Summary: The formation of pseudocapsule type homo- and heteromultinuclear complexes of calix[6]-mono-crown-5 (H-4 L) encapsulating from 4 to 6 alkali metal ions is reported. The complexes are formed through interligand interactions and C-H center dot center dot center dot pi interactions. The preference for metal ions and their positions in forming the pseudocapsules are demonstrated. Solution studies support the superior binding affinity of Rb+ over K+ toward the crown loop.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Hiroki Horita, Izumi Sato, Huiyeong Ju, Eunji Lee, Mari Ikeda, Shunsuke Kuwahara, Yoichi Habata
Summary: A 14-membered cyclic compound (3) containing amide, amino, and carbamate groups was obtained by serendipity in the oily residue after the separation of two different compounds (2a and 2b). The structure of compound 3 was found to involve a CO2 insertion between positions 3 and 4 of compound 2a. The selectivity and kinetic behavior of compound 3 and another compound (5) were also reported.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Review
Chemistry, Physical
Goeun Lee, Sang Eon Jun, Yujin Kim, In-Hyeok Park, Ho Won Jang, Sun Hwa Park, Ki Chang Kwon
Summary: Developing cost-effective, highly catalytic active, and stable electrocatalysts in alkaline electrolytes is crucial for efficient anion-exchange membrane water electrolysis (AEMWE). Metal oxides/hydroxides have emerged as promising electrocatalysts for water splitting due to their abundance and tunable electronic properties. However, achieving efficient catalytic performance with single metal oxide/hydroxide-based electrocatalysts is challenging. This review focuses on advanced strategies such as nanostructure engineering, heterointerface engineering, single-atom catalysts, and chemical modification to synthesize multicomponent metal oxide/hydroxide-based materials. The challenges and future prospects of these electrocatalysts are discussed.
Article
Chemistry, Multidisciplinary
Hiroki Horita, Fumika Nemoto, Izumi Sato, Mari Ikeda, Shunsuke Kuwahara, Yoichi Habata
Summary: The ligands of tris(tetra-armed cyclen) and pentakis(tetra-armed cyclen) were synthesized and their structures were confirmed by various analytical techniques. Upon addition of Ag+ ions, the ligands formed complexes with stoichiometries of 1:1 to 1:3 and 1:1 to 1:5 for the tris and pentakis ligands, respectively. The association constants between the ligands and Ag+ ions were estimated using UV-vis spectroscopy.
JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Hiroki Horita, Ki-Min Park, Mari Ikeda, Shunsuke Kuwahara, Yoichi Habata
Summary: Bis- and tris(tetra-armed cyclen)s with electron-rich or electron-deficient aromatic side arms were synthesized for regioselective coordination with Ag+ ions. The coordination behavior was determined by the electron density variation in the aromatic side arms. Different complexes were formed depending on the substituents and locations of the cyclen units. The results demonstrated the possibility of achieving regioselective coordination with Ag+ ions by tuning the electron density on the aromatic side arms in bis- or tris(tetra-armed cyclen)s.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Seulgi Kim, Jaewook An, Heekyoung Choi, Sung Ho Jung, Shim Sung Lee, In-Hyeok Park
Summary: In this study, an enantiopure pair of metal-organic frameworks (MOFs) capable of [2 + 2] cycloaddition reaction was synthesized by self-assembly of a bipyridyl olefin ligand and either d-cam or l-cam. These chiral MOFs (CMOFs) underwent a [2 + 2] photocycloaddition reaction, which is reported for the first time. The photoreactive homochiral network materials with diverse topologies and applications presented a new perspective.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Jaewook An, Jihye Oh, Uma Kurakula, Dong Hee Lee, Aditya Choudhury, Eunji Lee, Raghavender Medishetty, In-Hyeok Park
Summary: In this study, two novel photoreactive Zn(II) MOFs were synthesized and showed structural transformations upon UV irradiation, resulting in the formation of higher dimensional materials.
Article
Crystallography
Huiyeong Ju, Dong Hee Lee, Seulgi Kim, Joon Rae Kim, Yunji Kang, Eunji Lee, In-Hyeok Park
Summary: Two Hg(II) complexes of a NO2S2-macrocycle and its oxidized ligand with different stoichiometries were prepared using different crystallization methods. The structures and binding characteristics of these complexes were studied using NMR titration in solution.
Article
Crystallography
Dong Hee Lee, In-Hyeok Park
Summary: The preparations and structural characteristics of three-dimensional Zn(II) metal-organic frameworks (MOFs) with dipyridyl-olefin and tricarboxylate are reported. Depending on the temperature or mole-ratio variations, self-interpenetrated, noninterpenetrated, and fourfold interpenetrated structures were generated with different molecular building blocks. Interestingly, although all three MOFs contain the same metal cation, anion, and spacer ligand, they show different emissions due to structure and connectivity.
Article
Crystallography
Dong Hee Lee, Jaewook An, Jihye Oh, In-Hyeok Park
Summary: The combination of 4-styrylpyridine (spy) and 1-adamantanecarboxylic acid (Hadc) was used to react with Zn(II) and Cu(II) nitrates, and the photoreactivity of the resulting products was compared and discussed. The zinc(II) complex was found to be photoinert, while the copper(II) complex exhibited photoreactivity and formed a cyclobutene ring via [2+2] photodimerization. The crystal structures of the products also supported their photoreactivity.
Article
Chemistry, Multidisciplinary
Hyeong-Hwan Lee, Jihye Oh, Shim Sung Lee, In-Hyeok Park
Summary: A novel flexible tripyridyl disulfide ligand (L) was synthesized and used to form different types of one-dimensional coordination polymers with copper and silver salts. The silver complexes showed enhanced emissions, while the copper complex did not emit light.
Article
Chemistry, Multidisciplinary
Yoichi Habata, Ayumi Wada, Eunji Lee, Huieyong Ju, Yuki Yoshiba, Hiroki Horita, Jun-ichi Ishii, Mari Ikeda, Shunsuke Kuwahara
Summary: In this study, we describe the formation of tetra-armed cyclen (L) inclusion crystals, capable of selectively binding acetonitrile, from acetonitrile-organic mixed solvents. We observed that L acts as an acetonitrile selective molecular sponge.
