Inhibition of the mTOR pathway: A new mechanism of β cell toxicity induced by Tacrolimus

Raptor regulates functional maturation of murine beta cells

(2017) Qicheng Ni et al.   Nature Communications

Rapamycin-induced G1 cell cycle arrest employs both TGF-β and Rb pathways

(2015) Amrita Chatterjee et al.   CANCER LETTERS

Calcium release channel RyR2 regulates insulin release and glucose homeostasis

(2015) Gaetano Santulli et al.   JOURNAL OF CLINICAL INVESTIGATION

Cambios en la homeostasis de la glucosa y la proliferación de la célula beta pancreática tras el cambio a ciclosporina en la diabetes inducida por tacrolimus

(2015) Ana Elena Rodríguez-Rodríguez et al.   NEFROLOGIA

Risk of Metabolic Complications in Kidney Transplantation After Conversion to mTOR Inhibitor: A Systematic Review and Meta-Analysis

(2014) N. Murakami et al.   AMERICAN JOURNAL OF TRANSPLANTATION

MafA is critical for maintenance of the mature beta cell phenotype in mice

(2014) Wataru Nishimura et al.   DIABETOLOGIA

The Higher Diabetogenic Risk of Tacrolimus Depends on Pre-Existing Insulin Resistance. A Study in Obese and Lean Zucker Rats

(2013) A. E. Rodriguez-Rodriguez et al.   AMERICAN JOURNAL OF TRANSPLANTATION

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

The ORION Study: Comparison of Two Sirolimus-Based Regimens versus Tacrolimus and Mycophenolate Mofetil in Renal Allograft Recipients

(2011) S. M. Flechner et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Effect of different immunosuppressive regimens on the evolution of distinct metabolic parameters: evidence from the Symphony study

(2011) K. Claes et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Cyclosporine, tacrolimus and sirolimus retain their distinct toxicity profiles despite low doses in the Symphony study

(2010) H. Ekberg et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Sirolimus Is Associated with New-Onset Diabetes in Kidney Transplant Recipients

(2008) O. Johnston et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY