Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, and Clinical Effect of Danirixin in Adults With Acute, Uncomplicated Influenza

Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2

(2017) Jakob Busch-Petersen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Influenza in the Asia-Pacific region: Findings and recommendations from the Global Influenza Initiative

(2017) Benjamin J. Cowling et al.   VACCINE

Rates of neutropenia in adults with influenza A or B: a retrospective analysis of hospitalised patients in South East Queensland during 2015

(2016) P. Higgins et al.   INTERNAL MEDICINE JOURNAL

The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756) − a selective CXCR2 antagonist − in healthy adult subjects

(2015) Bruce E. Miller et al.   BMC Pharmacology & Toxicology

Association of interleukin-8 and neutrophils with nasal symptom severity during acute respiratory infection

(2014) Kelsey M. Henriquez et al.   JOURNAL OF MEDICAL VIROLOGY

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

Humoral immunity and delayed-type hypersensitivity in healthy subjects treated for 30days with MK-7123, a selective CXCR2 antagonist

(2013) Michael Seiberling et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pathogenesis of influenza-induced acute respiratory distress syndrome

(2013) Kirsty R Short et al.   LANCET INFECTIOUS DISEASES

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans

(2011) Aili L. Lazaar et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Development and Validation of the Influenza Intensity and Impact Questionnaire (FluiiQ™)

(2011) Richard H. Osborne et al.   VALUE IN HEALTH

Platelet-Activating Factor Receptor Plays a Role in Lung Injury and Death Caused by Influenza A in Mice

(2010) Cristiana C. Garcia et al.   PLoS Pathogens

Lung Pathology in Fatal Novel Human Influenza A (H1N1) Infection

(2009) Thais Mauad et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Seasonal Influenza in Adults and Children—Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management: Clinical Practice Guidelines of the Infectious Diseases Society of America

(2009) Scott A. Harper et al.   CLINICAL INFECTIOUS DISEASES