Article
Medicine, General & Internal
Janine Wirkner, Matthias Scheuch, Thomas Dabers, Sabrina Freiin von Rheinbaben, Beate Fiene, Simone Aymanns, Karlhans Endlich, Nicole Endlich, Uwe Lendeckel, Rainer Rettig, Hans Joergen Grabe, Sylvia Stracke
Summary: This study examined various factors influencing health-related quality of life (HRQOL) in chronic kidney disease (CKD) patients, with a focus on the impact of dialysis, depression, and diabetes. The results highlighted the importance of recognizing and treating depression to improve HRQOL and potentially enhance patient outcomes and reduce hospitalization rates.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Urology & Nephrology
Chandana Guha, Anita van Zwieten, Rabia Khalid, Siah Kim, Amanda Walker, Anna Francis, Madeleine Didsbury, Armando Teixeira-Pinto, Belinda Barton, Chanel Prestidge, Emily Lancsar, Fiona Mackie, Joseph Kwon, Kirsten Howard, Kylie-Ann Mallitt, Martin Howell, Allison Jaure, Alison Hayes, Rakhee Raghunandan, Stavros Petrou, Suncica Lah, Steven McTaggart, Jonathan C. Craig, Germaine Wong
Summary: This multi-center longitudinal cohort study aimed to assess the trajectories of health-related quality of life (HRQoL) in children with chronic kidney disease (CKD) over time. The results showed that the HRQoL scores differed between children with different CKD stages, and the transition from dialysis to transplantation was significantly associated with the improvement in HRQoL. Children with CKD stage 1-5 and transplant recipients at baseline had stable HRQoL over time.
KIDNEY INTERNATIONAL
(2023)
Article
Medicine, General & Internal
Yun Soo Hong, Hoon Kim, Di Zhao, Ajin Cho
Summary: This study using KNHANES data found that HRQoL in patients with DM worsened with the severity of CKD stages, with pain/discomfort being the most common problem among DM patients. As CKD advanced, patients were more likely to experience problems in all dimensions of EQ-5D, except for the anxiety/depression dimension.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nursing
Harith Eranga Yapa, Louise Purtell, Shirley Chambers, Ann Bonner
Summary: The study aimed to test the revised Wilson and Cleary model's ability to identify factors contributing to health-related quality of life in chronic kidney disease patients. The results showed that biological function, symptoms, general health perceptions, and environmental characteristics directly or indirectly influenced health-related quality of life. This model can help nurses identify these factors early and implement effective management strategies to improve patients' quality of life.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Dermatology
Monica Hernandez Alava, Alessandro Sasso, Pann Ei Hnynn Si, Matthew Gittus, Richard Powell, Louese Dunn, Praveen Thokala, James Fotheringham
Summary: This study investigated the impact of chronic kidney disease-associated pruritus on patients' quality of life. The findings suggest that in addition to the severity of itching, it is important to consider how the individual is affected physically, mentally, and socially by the itching, which is more closely related to generic quality of life measurement.
ACTA DERMATO-VENEREOLOGICA
(2023)
Review
Medicine, General & Internal
Natalia Dryjanska, Katarzyna Kilis-Pstrusinska
Summary: Depression is a significant health problem, especially among children and adolescents, and it is more prevalent in patients with chronic diseases such as chronic kidney disease (CKD). This review discusses the high risk of developing depression in adolescents and females, and the impact of depression on the quality of life of children and adolescents with CKD. The stage of the disease, age of CKD diagnosis, and type of treatment significantly affect the health-related quality of life (HRQoL) and caregiver burden. Screening for depression is recommended for CKD patients, and transdiagnostic tools should be used for symptom alleviation. Preventative strategies should be considered for children at risk of developing depression.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Davide Maria Cammisuli, Gabriele Cipriani, Emanuele Maria Giusti, Gianluca Castelnuovo
Summary: Reminiscence therapy (RT) has the potential to be an effective non-pharmacological therapy for elderly patients with Alzheimer's disease (AD). It can improve cognitive function, ameliorate depression, and enhance the quality of life of individuals with dementia. However, more research with long-term follow-up is needed to confirm these findings.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Urology & Nephrology
Kendra E. Wulczyn, Sophia H. Zhao, Eugene P. Rhee, Sahir Kalim, Tariq Shafi
Summary: This study found an association between decline in kidney function and worsening of uremic symptom severity in patients with chronic kidney disease. However, the magnitude of these changes is small and of uncertain clinical significance.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Transplantation
Murilo Guedes, Daniel Muenz, Jarcy Zee, Marcelo Barreto Lopes, Sandra Waechter, Benedicte Stengel, Ziad A. Massy, Elodie Speyer, Carole Ayav, Fredric Finkelstein, Ricardo Sesso, Ronald L. Pisoni, Bruce M. Robinson, Roberto Pecoits-Filho
Summary: The study found that low TSAT levels, as well as both low TSAT with low ferritin and low TSAT with high ferritin, are associated with worse physical HRQoL in NDD-CKD patients, even after accounting for Hb level. Interventional studies of iron therapy on HRQoL among NDD-CKD individuals are needed to confirm these findings.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Pediatrics
Peace D. Imani, Judith Aujo, Sarah Kiguli, Poyyapakkam Srivaths, Eileen D. Brewer
Summary: Limited data exist about causes of chronic kidney disease (CKD) and impact on health-related quality of life (HRQoL) in African children. Our study in Ugandan children aged 0-18 years found that congenital anomalies of the urinary tract (CAKUT) were the main cause of CKD, with most children presenting at late CKD stages 3b-5, resulting in significantly lower HRQoL compared to children with non-CKD. Advanced CKD stages, non-parent caregiver, vitamin D deficiency, and anemia were identified as predictors of lower HRQoL.
PEDIATRIC NEPHROLOGY
(2021)
Article
Nursing
Harith Eranga Yapa, Louise Purtell, Shirley Chambers, Ann Bonner
Summary: This study aimed to compare symptoms and health-related quality of life in chronic kidney disease patients and found that as kidney function deteriorated, symptoms worsened and health-related quality of life decreased. Early identification and proactive management by nurses are crucial for reducing symptom burden and improving quality of life in these patients.
JOURNAL OF CLINICAL NURSING
(2021)
Article
Gastroenterology & Hepatology
Marlen I. Castellanos-Fernandez, Susana A. Borges-Gonzalez, Maria Stepanova, Mirtha E. Infante-Velazquez, Caridad Ruenes-Domech, Sila M. Gonzalez-Suero, Zaily Dorta-Guridi, Enrique R. Arus-Soler, Andrei Racila, Zobair M. Younossi
Summary: This study assessed health-related quality of life (HRQL) in Cuban patients with compensated chronic liver disease (CLD). The results showed that patients with HCV and autoimmune liver diseases (AILD) had the worst PRO scores, likely due to severe underlying liver disease and/or extrahepatic manifestations. Male gender and regular exercise were predictors of better HRQL, while fatigue, abdominal pain, anxiety, and depression were strong independent predictors of HRQL impairment.
ANNALS OF HEPATOLOGY
(2021)
Review
Urology & Nephrology
Eva Segura-Orti, Pelagia Koufaki, Evangelia Kouidi
Summary: Improving the health status of people with chronic kidney disease through physical activity or exercise interventions is challenging due to the lack of systematic recording and monitoring of physical activity and physical function attributes. Evaluating physical activity, physical function, and health-related quality of life is important to enhance overall health outcomes for CKD patients, as physical inactivity and impaired function can lead to lower quality of life.
CLINICAL KIDNEY JOURNAL
(2021)
Article
Public, Environmental & Occupational Health
Pengfei Zhou, Shuai Wang, Ya Yan, Qiang Lu, Jiaxing Pei, Wang Guo, Xiaoguang Yang, Yunming Li
Summary: With the aging of the Chinese population, the prevalence of depression and chronic diseases is increasing among middle-aged and older adults. This study examined the association between chronic diseases and depression in this population. The findings showed that having chronic diseases increased the risk of depression, and the risk further increased with the number of chronic diseases. Diabetes, kidney disease, digestive diseases, and arthritis significantly increased the risk of depression in middle-aged and older adults.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Urology & Nephrology
Nicholas C. Chesnaye, Yvette Meuleman, Esther N. M. de Rooij, Ellen K. Hoogeveen, Friedo W. Dekker, Marie Evans, Agneta A. Pagels, Fergus J. Caskey, Claudia Torino, Gaetana Porto, Maciej Szymczak, Christiane Drechsler, Christoph Wanner, Kitty J. Jager
Summary: This study found that among older men and women with advanced CKD, women had lower health-related quality of life at baseline, but men experienced a more rapid decline in health-related quality of life over time. This difference was partly explained by adjusting for important covariates, such as eGFR decline. Higher serum phosphate, lower hemoglobin, and the presence of preexisting diabetes were also associated with lower health-related quality of life in men but to a lesser extent in women.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)