Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrads of controls with subjects diagnosed with schizophrenia, bipolar or major depressive disorder

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Increased stereotypy in conditional Cxcr4 knockout mice

(2016) Tyler Cash-Padgett et al.   NEUROSCIENCE RESEARCH

Transcriptome-wide mega-analyses reveal joint dysregulation of immunologic genes and transcription regulators in brain and blood in schizophrenia

(2016) Jonathan L. Hess et al.   SCHIZOPHRENIA RESEARCH

Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A “central hub” in schizophrenia pathophysiology?

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Molecular Mechanisms and Timing of Cortical Immune Activation in Schizophrenia

(2015) David W. Volk et al.   AMERICAN JOURNAL OF PSYCHIATRY

Lower Glutamic Acid Decarboxylase 65-kDa Isoform Messenger RNA and Protein Levels in the Prefrontal Cortex in Schizoaffective Disorder but Not Schizophrenia

(2015) Jill R. Glausier et al.   BIOLOGICAL PSYCHIATRY

Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes

(2015) J A Brown et al.   MOLECULAR PSYCHIATRY

Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder

(2015) D Arion et al.   MOLECULAR PSYCHIATRY

Evaluation of TrkB and BDNF transcripts in prefrontal cortex, hippocampus, and striatum from subjects with schizophrenia, bipolar disorder, and major depressive disorder

(2015) Veronica Reinhart et al.   NEUROBIOLOGY OF DISEASE

Effects of psychotropic drugs on inflammation: consequence or mediator of therapeutic effects in psychiatric treatment?

(2015) David Baumeister et al.   PSYCHOPHARMACOLOGY

Chemokine receptors and cortical interneuron dysfunction in schizophrenia

(2015) David W. Volk et al.   SCHIZOPHRENIA RESEARCH

Psychiatric Disorders From Childhood to Adulthood in 22q11.2 Deletion Syndrome: Results From the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome

(2014) Maude Schneider et al.   AMERICAN JOURNAL OF PSYCHIATRY

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

Deficits in microRNA-mediated Cxcr4/Cxcl12 signaling in neurodevelopmental deficits in a 22q11 deletion syndrome mouse model

(2013) M. Toritsuka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress in Puberty Unmasks Latent Neuropathological Consequences of Prenatal Immune Activation in Mice

(2013) S. Giovanoli et al.   SCIENCE

Cortico-basal ganglia networks subserving goal-directed behavior mediated by conditional visuo-goal association

(2013) Eiji Hoshi   Frontiers in Neural Circuits

Gene expression profiling by mRNA sequencing reveals increased expression of immune/inflammation-related genes in the hippocampus of individuals with schizophrenia

(2013) Y Hwang et al.   Translational Psychiatry

Maternal immune activation causes age- and region-specific changes in brain cytokines in offspring throughout development

(2012) Paula A. Garay et al.   BRAIN BEHAVIOR AND IMMUNITY

A review of anti-inflammatory agents for symptoms of schizophrenia

(2012) William R Keller et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia

(2012) S G Fillman et al.   MOLECULAR PSYCHIATRY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Cxcr4 regulation of interneuron migration is disrupted in 22q11.2 deletion syndrome

(2012) D. W. Meechan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for sustained elevation of IL-6 in the CNS as a key contributor of depressive-like phenotypes

(2012) S J Sukoff Rizzo et al.   Translational Psychiatry

Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia

(2011) Michael R. Barnes et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The first decade and beyond of transcriptional profiling in schizophrenia

(2011) P. Adolfo Sequeira et al.   NEUROBIOLOGY OF DISEASE

CXCR4 and CXCR7 Have Distinct Functions in Regulating Interneuron Migration

(2011) Yanling Wang et al.   NEURON

High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia

(2011) Dheeraj Malhotra et al.   NEURON

Glutamate signaling in the pathophysiology and therapy of schizophrenia

(2011) Chieh-Hsin Lin et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

GABA Neuron Alterations, Cortical Circuit Dysfunction and Cognitive Deficits in Schizophrenia

(2011) Guillermo Gonzalez-Burgos et al.   NEURAL PLASTICITY

Expression of Interneuron Markers in the Dorsolateral Prefrontal Cortex of the Developing Human and in Schizophrenia

(2010) Samantha J. Fung et al.   AMERICAN JOURNAL OF PSYCHIATRY

Maternal Infection and Schizophrenia: Implications for Prevention

(2010) A. S. Brown et al.   SCHIZOPHRENIA BULLETIN

Molecular Determinants of Dysregulated GABAergic Gene Expression in the Prefrontal Cortex of Subjects with Schizophrenia

(2009) Nikolaos Mellios et al.   BIOLOGICAL PSYCHIATRY

Functional integration between the posterior hippocampus and prefrontal cortex is impaired in both first episode schizophrenia and the at risk mental state

(2009) S. Benetti et al.   BRAIN

Disturbed functional connectivity within brain networks subserving domain-specific subcomponents of working memory in schizophrenia: Relation to performance and clinical symptoms

(2009) Ilona Henseler et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function

(2009) P R Maycox et al.   MOLECULAR PSYCHIATRY

The Reward Circuit: Linking Primate Anatomy and Human Imaging

(2009) Suzanne N Haber et al.   NEUROPSYCHOPHARMACOLOGY

IL-6 Mediated Degeneration of Forebrain GABAergic Interneurons and Cognitive Impairment in Aged Mice through Activation of Neuronal NADPH Oxidase

(2009) Laura L. Dugan et al.   PLoS One

Alterations in Somatostatin mRNA Expression in the Dorsolateral Prefrontal Cortex of Subjects with Schizophrenia or Schizoaffective Disorder

(2008) Harvey M. Morris et al.   CEREBRAL CORTEX

Interleukin-6 Mediates the Increase in NADPH-Oxidase in the Ketamine Model of Schizophrenia

(2008) M. M. Behrens et al.   JOURNAL OF NEUROSCIENCE

Systems Biology and Complex Neurobehavioral Traits

(2008) I. Giegling et al.   PHARMACOPSYCHIATRY