Article
Critical Care Medicine
Amanullah Haidary, Jason S. Hoellwarth, Kevin Tetsworth, Atiya Oomatia, Munjed Al Muderis
Summary: Transcutaneous osseointegration for amputees (TOFA) is a surgical method that provides improved quality of life and mobility for amputees. This study investigates the safety and compatibility of TOFA for patients with a history of burns, and finds that it is a safe and viable option.
Article
Medicine, General & Internal
Thomas Krauskopf, Torben Lauck, Britta Meyer, Lukas Klein, Marc Mueller, Johanna Kubosch, Georg Herget, Vinzenz von Tscharner, Jennifer Ernst, Thomas Stieglitz, Cristian Pasluosta
Summary: This observational study explored how bone anchoring affects neuromuscular parameters in a patient with a unilateral transfemoral amputation. The results showed that after the bone anchoring surgery, muscle co-activation and electromyography (EMG) intensity approached the levels of able-bodied individuals, suggesting a shift in the patient's neuromuscular profile towards that of healthy individuals.
ANNALS OF MEDICINE
(2023)
Article
Neurosciences
Vera Kooiman, Lisanne Haket, Nico Verdonschot, Ruud Leijendekkers, Vivian Weerdesteyn
Summary: Comparative analysis between satisfied transfemoral socket-suspended prosthesis (SSP) users, satisfied transfemoral bone-anchored prosthesis (BAP) users, and able-bodied individuals (AB) revealed that SSP users had higher oxygen consumption and trunk dynamics compared to AB during walking. BAP users had intermediate results between SSP users and AB, but no significant differences were found. Greater trunk excursions were associated with higher oxygen consumption, while a higher degree of pistoning in SSP users was related to larger trunk dynamics. These findings suggest that evaluating CoM and trunk dynamics, as well as pistoning, could help determine the suitability of BAP for SSP users and potentially benefit a larger population.
Article
Psychiatry
Daniel Dyball, Alexander N. Bennett, Susie Schofield, Paul Cullinan, Christopher J. Boos, Anthony M. J. Bull, Simon Wessely, Sharon A. M. Stevelink, Nicola T. Fear
Summary: This study aimed to evaluate the long-term psychosocial outcomes of UK armed forces personnel who sustained combat injuries in Afghanistan. The findings showed that combat-injured personnel had higher rates of probable post-traumatic stress disorder (PTSD), depression, anxiety, and mental health-associated multimorbidity compared to uninjured personnel. The type of injury sustained also influenced the mental health outcomes.
Review
Orthopedics
Norbert Kang, Yazan Al-Ajam, Phyllis Keen, Alexander Woollard, Hannah Steinitz, Joanna Farrant, Geoffrey Chow
Summary: This article discusses the radiological evaluation of osseointegrated implants as an alternative to traditional prostheses. Radiologists are guided on providing the necessary information for surgeons and prosthetists and are also informed about potential complications and their radiological appearances.
SKELETAL RADIOLOGY
(2023)
Article
Chemistry, Analytical
Dylan den Hartog, Jaap Harlaar, Gerwin Smit
Summary: This study investigated the detection and classification of stumbling events using a single IMU and machine learning algorithms, with SVM algorithms achieving high accuracy rates and leading to the development of a stumble detection app named Stumblemeter.
Article
Materials Science, Multidisciplinary
Hongyan Tang, Qing Li, Min Li, Xuenan Gu, Chengkung Cheng, Yubo Fan
Summary: This study investigated the potential of a magnesium alloy with low combined addition of strontium and lanthanum for alveolar bone fixation screws. The alloy exhibited good mechanical properties, moderate degradation rate, and promoted osteogenesis. In addition, the alloy showed promising biocompatibility and osseointegration in the subgingival environment. These findings highlight the great potential of the Mg-Sr-La alloy for dental clinical applications.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Biomedical
Per Kjellin, Karin Danielsson, Joakim Hakansson, Karin Agrenius, Therese Andersson, Patrik Stenlund
Summary: A biomechanical method was developed and evaluated to study the integration of implants into porcine skin in an ex vivo model. Results showed that using nanosized hydroxyapatite (HA) on titanium and PEEK could increase pullout force, while using nanosized zirconium phosphate (ZrP) did not have the same effect. Pullout force was inversely proportional to epidermal downgrowth (ED) and tissue to implant contact (TIC) was significantly higher for PEEK compared to titanium.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2022)
Article
Materials Science, Multidisciplinary
Zhuocheng Lyu, Yaochao Zhao, Shicheng Huo, Fan Wang, Xiangchao Meng, Zhiguo Yuan, Teng Long, You Wang
Summary: Implant-associated infection and insufficient implant osseointegration are common causes of implant failure. In this study, a multi-functional bioactive ion, copper (Cu), was incorporated into the polydopamine (PDA) coating on polyetheretherketone (PEEK) surfaces. The DA-Cu-II coated PEEK surfaces showed superior abilities of osteogenesis, angiogenesis, and antibiosis, as well as immunomodulatory effects. The coating also induced a mild and necessary inflammatory response, exhibiting excellent antibacterial activity and osseointegration. The findings suggest that the DA-Cu-II coated PEEK has great potential for orthopedic implants and provides new insights into novel modification strategies for PEEK materials.
MATERIALS & DESIGN
(2022)
Article
Surgery
Michael K. Dalton, Kyle N. Remick, Michael Mathias, Quoc-Dien Trinh, Zara Cooper, Eric A. Elster, Joel S. Weissman
Summary: Low surgical volume in the US Military Health System has been identified as a challenge to military surgeon readiness. The study found that since 2015, the number of surgical procedures and KSA metric points in military hospitals has decreased, while increasing in civilian facilities. The proportion of military general surgeons meeting the KSA metric readiness threshold has also decreased.
Article
Biotechnology & Applied Microbiology
Siyi Huang, Tao Ji, Xiaodong Tang, Wei Guo
Summary: This study proposes a 3D-printed axial compressive endoprosthesis for improving metaphyseal fixation after bone tumor resection. Biomechanical analysis shows that the endoprosthesis provides good initial stability and facilitates osseointegration.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Nupur Kohli, Konstantinos Theodoridis, Thomas A. G. Hall, Inigo Sanz-Pena, David C. A. Gaboriau, Richard J. van Arkel
Summary: This study aimed to evaluate a lab-based bioreactor model for assessing bone remodelling onto, into or around new implant technologies. The results showed that the samples cultured in the bioreactor exhibited greater tissue ongrowth, ingrowth and remodelling compared to those in static culture conditions. In addition, the mechanically tested samples from the bioreactor had approximately three times greater fixation strength.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Surgery
Matthew Vuoncino, Justin Scheidt, David S. Kauvar
Summary: This study aimed to investigate the relationship between treatment time and amputation risk in military femoropopliteal arterial injuries. The results showed that a longer time from injury to initial revascularization was associated with an increased risk of limb loss. Revascularization within 3 hours of injury resulted in a lower amputation rate, while treatment after 9 hours had a higher amputation rate.
JOURNAL OF VASCULAR SURGERY
(2023)
Review
Biotechnology & Applied Microbiology
Zhanqi Wei, Ze Zhang, Wei Zhu, Xisheng Weng
Summary: Polyetheretherketone (PEEK) has been widely used in the medical field as an implant material, especially in bone tissue engineering and orthopedic surgery, recently. Many approaches have been applied to improve its performance, including the modulation of physical morphology, chemical composition and antimicrobial agents. PEEK implants have shown better outcomes than traditional metal implants in studies on spine surgery, joint surgery, and trauma repair.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Carly Sullivan, Joshua Zuckerman, Daniel James, Karl Maritato, Emily Morrison, Riccarda Schuenemann, Ron Ben-Amotz
Summary: The purpose of this study was to report the surgical and medical management approaches for proximal tibial metaphyseal fractures (PTMF) and their short-term outcomes. The study reviewed medical records of immature dogs with PTMF and collected data on their treatments and complications. The results showed that surgical management had a more predictable outcome compared to conservative management, although conservative treatment could lead to complications.