Article
Neurosciences
Wei Cui, Li Xu, Lin Huang, Yang Tian, Yan Yang, Yamei Li, Qian Yu
Summary: The study aims to explore the characteristics of gut microbiota changes over time after stroke. The researchers compared the clinical data and gut microbiota of stroke patients and healthy subjects in two phases. The results showed that gut dysbiosis still existed in patients in the subacute phase and convalescent phase of stroke, and gradually improved with the recovery of stroke. There is a strong correlation between gut microbiota and cognitive function after stroke.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Environmental Sciences
Aoyun Li, Yajing Wang, Yuanyuan He, Bingxian Liu, Mudassar Iqbal, Khalid Mehmood, Tariq Jamil, Yung-Fu Chang, Lianmei Hu, Ying Li, Jianying Guo, Jiaqiang Pan, Zhaoxin Tang, Hui Zhang
Summary: Fluorine and its compounds from industrial production and coal combustion can cause contamination of air, water, and soil, posing a threat to public health through accumulation in animals, plants, and humans via food chain. Exposure to fluoride resulted in damaged intestinal structure and altered gut microbial composition in ducks.
Article
Microbiology
Virginie Lemieux-Labonte, Chloe Vigliotti, Zoran Tadic, Beck Wehrle, Philippe Lopez, Eric Bapteste, Francois-Joseph Lapointe, Donovan P. German, Anthony Herrel
Summary: Dietary changes are important factors driving variation in mammalian gut microbiota composition, but other factors such as insularity and population of origin also contribute to differences in microbial composition.
Article
Biotechnology & Applied Microbiology
Shuangshuang Wang, Feng Song, Haoyu Gu, Zhilong Shu, Xiaowen Wei, Ke Zhang, Yuxiang Zhou, Lanrui Jiang, Zefei Wang, Jienan Li, Haibo Luo, Weibo Liang
Summary: This study investigated the gut microbiota of healthy adults with different traits. The results showed differences in gut microbiota composition between male and female subjects. Additionally, the gut microbiota composition was able to distinguish between different BMI groups. At the phylum level, specific phyla were found to be increased in different BMI groups for both males and females. At the genus level, several distinct genera were identified across BMI groups. The accuracy of predicting body type using a linear regression model was 74%.
MICROBIAL CELL FACTORIES
(2022)
Article
Biotechnology & Applied Microbiology
Shoichiro Kameoka, Daisuke Motooka, Satoshi Watanabe, Ryuichi Kubo, Nicolas Jung, Yuki Midorikawa, Natsuko O. Shinozaki, Yu Sawai, Aya K. Takeda, Shota Nakamura
Summary: The study compared 192 Japanese volunteers' fecal 16S analysis data using modified V1-V2 and standard V3-V4 primers. Results showed that the bacterial composition derived from the V34 region might differ from the actual abundance, suggesting that the modified V12 primer set is more desirable for analyzing the Japanese gut microbiota.
Article
Biotechnology & Applied Microbiology
Rongrong Liao, Xinhua Xie, Yuhua LV, Jianjun Dai, Yuexia Lin, Lihui Zhu
Summary: The study revealed that gut microbiota diversity significantly increased in lambs after weaning, with a notable increase in butyrate-producing bacteria and fiber degradation-associated bacteria. Correlation analysis also showed associations between certain gut bacteria and serum lipid metabolites in weaned lambs.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Jingjing Liu, Wei Dong, Jian Zhao, Jing Wu, Jinqiang Xia, Shaofei Xie, Xiaofeng Song
Summary: Through statistical analysis and correlation analysis, the study found that the intestinal flora of mice with colorectal inflammation or colorectal cancer significantly changed compared with healthy mice, with Muribaculaceae and Bacteroidaceae showing strong excluding interactions. The functional changes of the gut microbiota include the up-regulation of the cancers pathway and the down-regulation of the replication and repair pathways.
Article
Oncology
Areej A. Alhhazmi, Yahya A. Almutawif, Walaa A. Mumena, Shaima M. Alhazmi, Turki S. Abujamel, Ruba M. Alhusayni, Raghad Aloufi, Razan R. Al-Hejaili, Rahaf Alhujaily, Lama M. Alrehaili, Ruya A. Alsaedy, Rahaf H. Khoja, Wassal Ahmed, Mohamed F. Abdelmohsen, Waleed Mohammed-Saeid
Summary: This study analyzed the gut microbiota composition and enriched metabolic pathways in patients with late-stage colorectal cancer (CRC). The results showed significant differences in fecal microbiota between CRC patients and healthy individuals. Enriched populations of specific bacteria and metabolic pathways were found in CRC patients, suggesting their potential role in the development of advanced CRC tumors.
Article
Environmental Sciences
Zhibo Zeng, Wen Yue, Cermon Kined, PengPeng Wang, Ran Liu, Jing Liu, Xinzhu Chen
Summary: This study found that Bacillus licheniformis could effectively restore gut microbial dysbiosis and inflammation levels induced by ceftriaxone sodium treatment, which is important for maintaining intestinal health.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Microbiology
Qingyi Zhu, Xu Yang, Yingying Zhang, Chunjian Shan, Zhonghua Shi
Summary: This study demonstrated that dysbiosis of the gut microbiome induced by maternal gestational diabetes mellitus (GDM) might play an important role in increased infant BMI during the first 12 months of life. Specific genera were found to be negatively associated with infant BMI. Furthermore, the changes in meconium microbiota acted as a mediator between GDM and infant BMI. Therefore, gut microbiome interventions may be a novel technique to decrease the risk of GDM-induced childhood obesity.
Article
Immunology
Yanyan Que, Man Cao, Jianquan He, Qiang Zhang, Qiongyun Chen, Changsheng Yan, Aiqiang Lin, Luxi Yang, Zezhen Wu, Dan Zhu, Fengwu Chen, Zhangran Chen, Chuanxing Xiao, Kaijian Hou, Bangzhou Zhang
Summary: Research shows significant differences in microbial diversity between individuals with type 2 diabetes mellitus (T2DM) and controls, but not in microbial alpha diversity. Various operational taxonomic units (OTUs) and bacterial genera with significant odds ratios for T2DM were identified. The microbial characteristics of T2DM can be applied to other studies, improving detection accuracy and disease specificity for T2DM through training on multiple research studies.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Veterinary Sciences
Li Xi, Yumin Song, Xinxi Qin, Jincheng Han, Yung-Fu Chang
Summary: By comparing the gut microbial composition of healthy and diarrheic giraffes, this study found that diarrhea significantly impacts the diversity and composition of the gut microbiota by increasing the proportion of pathogenic bacteria and decreasing beneficial bacteria. It also identified specific changes in bacterial phyla and genera, providing insights for establishing prevention and treatment strategies for diarrhea in giraffes.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Microbiology
Limin Wei, Bo Zeng, Siyuan Zhang, Wei Guo, Feng Li, Jiangchao Zhao, Ying Li
Summary: This study compared and analyzed the gut microbiota of wild boar and its offspring using multi-omics technologies. The results showed that the gut microbiota of F4 exhibited host-like dominance with increased abundance of Lactobacillus and Bifidobacterium. Additionally, F4 showed similar metabolic pathways as Duroc. The findings provide reference data for the genetics and evolution of microbiota and microbial-assisted breeding theory.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Zijie Jin, Andy Ng, Corinne F. Maurice, David Juncker
Summary: MiCoMo is a low-cost, benchtop multi-bioreactor system that simulates the human colon environment, allowing for the study of gut microbial communities with high throughput and multiplexing capabilities.
Article
Infectious Diseases
Qi-Feng Gui, Hui-Lin Jin, Feng Zhu, Hai-Feng Lu, Qin Zhang, Jia Xu, Yun-Mei Yang, Chi Xiao
Summary: The study found that the gut microbiota of S. japonicum infection-induced liver cirrhosis patients is similar to that of healthy individuals, indicating that bacterial taxa cannot be used as non-invasive biomarkers for S. japonicum infection-induced liver cirrhosis.
INFECTIOUS DISEASES OF POVERTY
(2021)
Article
Endocrinology & Metabolism
Natalia I. Faccinetti, Luciano L. Guerra, Alberto Penas Steinhardt, Ruben F. Iacono, Gustavo D. Frechtel, Liliana Trifone, Edgardo Poskus, Aldana Trabucchi, Silvina N. Valdez
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2016)
Article
Multidisciplinary Sciences
Andrea Elena Iglesias Molli, Alberto Penas Steinhardt, Ariel Pablo Lopez, Claudio Daniel Gonzalez, Jorge Vilarino, Gustavo Daniel Frechtel, Gloria Edith Cerrone
Article
Genetics & Heredity
Alberto Penas-Steinhardt, Mariana L. Tellechea, Leonardo Gomez-Rosso, Fernando Brites, Gustavo D. Frechtel, Edgardo Poskus
BMC MEDICAL GENETICS
(2011)
Article
Cell Biology
Jimena Giudice, Lucia Soledad Barcos, Francisco F. Guaimas, Alberto Penas-Steinhardt, Luciana Giordano, Elizabeth A. Jares-Erijman, Federico Coluccio Leskow
CELL COMMUNICATION AND SIGNALING
(2013)
Article
Endocrinology & Metabolism
Alberto Penas Steinhardt, Florencia Aranguren, Mariana L. Tellechea, Leonardo A. Gomez Rosso, Fernando D. Brites, Maria T. Martinez-Larrad, Manuel Serrano-Rios, Gustavo D. Frechtel, Mariano J. Taverna
METABOLISM-CLINICAL AND EXPERIMENTAL
(2010)
Article
Biochemistry & Molecular Biology
F. S. Belforte, F. Coluccio Leskow, E. Poskus, A. Penas Steinhardt
MOLECULAR BIOLOGY REPORTS
(2013)
Article
Cardiac & Cardiovascular Systems
M. L. Tellechea, A. Penas Steinhardt, G. Rodriguez, M. J. Taverna, E. Poskus, G. Frechtel
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2013)
Article
Multidisciplinary Sciences
Alberto Penas-Steinhardt, Lucia Soledad Barcos, Fiorella Sabrina Belforte, Martha de Sereday, Jorge Vilarino, Claudio Daniel Gonzalez, Maria Teresa Martinez-Larrad, Mariana Lorena Tellechea, Manuel Serrano-Rios, Edgardo Poskus, Gustavo Daniel Frechtel, Federico Coluccio Leskow
Article
Paleontology
Roberto R. Pujana, Leandro C. A. Martinez, Juan L. Garcia Massini, Osvaldo Di Iorio, Alberto Penas Steinhardt
REVISTA BRASILEIRA DE PALEONTOLOGIA
(2014)
Article
Endocrinology & Metabolism
Silvina Yohena, Alberto Penas-Steinhardt, Clara Muller, Natalia Faccinett, Gloria E. Cerrone, Silvia Lovecchio, Edgardo Ridner, Silvina Valdez, Gustavo Frechtel
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2019)
Article
Multidisciplinary Sciences
Ignacio Dei-Cas, Florencia Giliberto, Leonela Luce, Hernan Dopazo, Alberto Penas-Steinhardt
SCIENTIFIC REPORTS
(2020)
Article
Microbiology
Pablo Aguilera, Maria Florencia Mascardi, Fiorella Sabrina Belforte, Ayelen Daiana Rosso, Sofia Quesada, Ignacio Llovet, Gregorio Iraola, Julieta Trinks, Alberto Penas-Steinhardt
Summary: The COVID-19 pandemic has had a significant impact on global public health, affecting the composition and diversity of the gut microbiota. This study compared the fecal microbiota of individuals in Buenos Aires before and during the pandemic and found significant differences in microbial diversity and community structure. These findings suggest that the microbiome of individuals has changed during the social isolation measures, and provide valuable insights for the development of interventions to improve public health in the post-pandemic era.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Ayelen D. Rosso, Pablo Aguilera, Sofia Quesada, Florencia Mascardi, Sebastian N. Mascuka, Maria C. Cimolai, Jimena Cerezo, Renata Spiazzi, Carolina Conlon, Claudia Milano, Gregorio M. Iraola, Alberto Penas-Steinhardt, Fiorella S. Belforte
Summary: Inflammatory bowel disease (IBD) presents a notable diagnostic challenge due to its clinical heterogeneity and treatment responses, especially in underdeveloped countries. This study characterized epigenetic biomarkers and gut microbial profiles in UC and CD patients in the Buenos Aires Metropolitan area for the first time, revealing differences between non-IBD controls and IBD patients.