Vaccination of hamsters with Opisthorchis viverrini extracellular vesicles and vesicle-derived recombinant tetraspanins induces antibodies that block vesicle uptake by cholangiocytes and reduce parasite burden after challenge infection

Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells

(2019) Eduardo de la Torre-Escudero et al.   PLoS Neglected Tropical Diseases

Extracellular vesicles from parasitic helminths and their potential utility as vaccines

(2018) Gebeyaw Getnet Mekonnen et al.   Expert Review of Vaccines

Extracellular vesicles induce protective immunity against Trichuris muris

(2018) R. K. Shears et al.   PARASITE IMMUNOLOGY

Hookworm Secreted Extracellular Vesicles Interact With Host Cells and Prevent Inducible Colitis in Mice

(2018) Ramon M. Eichenberger et al.   Frontiers in Immunology

Proteomic characterization of the internalization of Opisthorchis viverrini excretory/secretory products in human cells

(2017) Sujittra Chaiyadet et al.   PARASITOLOGY INTERNATIONAL

Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

(2017) Gillian Coakley et al.   Cell Reports

First report and molecular identification of Opisthorchis viverrini infection in human communities from Lower Myanmar

(2017) Win Pa Pa Aung et al.   PLoS One

Suppression of mRNAs encoding CD63 family tetraspanins from the carcinogenic liver fluke Opisthorchis viverrini results in distinct tegument phenotypes

(2017) Sujittra Chaiyadet et al.   Scientific Reports

Subcutaneous injection of exosomes reduces symptom severity and mortality induced by Echinostoma caproni infection in BALB/c mice

(2016) Maria Trelis et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Extracellular vesicles secreted by Schistosoma mansoni contain protein vaccine candidates

(2016) Javier Sotillo et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Advancing a vaccine to prevent human schistosomiasis

(2016) Maureen Merrifield et al.   VACCINE

Molecular characterization of S. japonicum exosome-like vesicles reveals their regulatory roles in parasite-host interactions

(2016) Lihui Zhu et al.   Scientific Reports

Excretory/secretory products of the carcinogenic liver fluke are endocytosed by human cholangiocytes and drive cell proliferation and IL6 production

(2015) Sujittra Chaiyadet et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Carcinogenic Liver Fluke Secretes Extracellular Vesicles That Promote Cholangiocytes to Adopt a Tumorigenic Phenotype

(2015) Sujittra Chaiyadet et al.   JOURNAL OF INFECTIOUS DISEASES

The Extracellular Vesicles of the Helminth Pathogen,Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis

(2015) Krystyna Cwiklinski et al.   MOLECULAR & CELLULAR PROTEOMICS

Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia

(2015) Michael J. Smout et al.   PLoS Pathogens

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

(2014) Amy H. Buck et al.   Nature Communications

Tetraspanins in Extracellular Vesicle Formation and Function

(2014) Zoraida Andreu et al.   Frontiers in Immunology

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma

(2013) Hina Kalra et al.   PROTEOMICS

Protective immunization of hamsters against Opisthorchis viverrini infection is associated with the reduction of TGF-β expression

(2012) Jutharat Jittimanee et al.   ACTA TROPICA

Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells

(2012) Antonio Marcilla et al.   PLoS One

The tumorigenic liver fluke Opisthorchis viverrini – multiple pathways to cancer

(2012) Banchob Sripa et al.   TRENDS IN PARASITOLOGY

Molecular Characterization of a Tetraspanin from the Human Liver Fluke, Opisthorchis viverrini

(2012) Supawadee Piratae et al.   PLoS Neglected Tropical Diseases

The current status of opisthorchiasis and clonorchiasis in the Mekong Basin

(2011) Paiboon Sithithaworn et al.   PARASITOLOGY INTERNATIONAL

Immune responsiveness and parasite-specific antibody levels in human hepatobiliary disease associated with Opisthorchis viverrini infection

(2010) M. R. HASWELL-ELKINS et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Efficacy and safety of mefloquine, artesunate, mefloquine–artesunate, tribendimidine, and praziquantel in patients with Opisthorchis viverrini: a randomised, exploratory, open-label, phase 2 trial

(2010) Phonepasong Soukhathammavong et al.   LANCET INFECTIOUS DISEASES

Pharmacotherapy of helminth infection

(2009) Erwin van den Enden   EXPERT OPINION ON PHARMACOTHERAPY

A Granulin-Like Growth Factor Secreted by the Carcinogenic Liver Fluke, Opisthorchis viverrini, Promotes Proliferation of Host Cells

(2009) Michael J. Smout et al.   PLoS Pathogens