What is mutation? A chapter in the series: How microbes “jeopardize” the modern synthesis

Periodic Variation of Mutation Rates in Bacterial Genomes Associated with Replication Timing

(2018) Marcus M. Dillon et al.   mBio

R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters

(2017) Liang Chen et al.   MOLECULAR CELL

Driving cancer evolution

(2017) Devon M Fitzgerald et al.   eLife

S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation

(2016) Lamia Wahba et al.   GENES & DEVELOPMENT

Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment

(2015) Susan E. Scanlon et al.   DNA REPAIR

The Spontaneous Mutation Rate in the Fission YeastSchizosaccharomyces pombe

(2015) Ashley Farlow et al.   GENETICS

Translesion Polymerases Drive Microhomology-Mediated Break-Induced Replication Leading to Complex Chromosomal Rearrangements

(2015) Cynthia J. Sakofsky et al.   MOLECULAR CELL

R loops: new modulators of genome dynamics and function

(2015) José M. Santos-Pereira et al.   NATURE REVIEWS GENETICS

The Spontaneous Mutation Rate in the Fission YeastSchizosaccharomyces pombe

(2015) Ashley Farlow et al.   GENETICS

Bursts of transposable elements as an evolutionary driving force

(2014) A. Belyayev   JOURNAL OF EVOLUTIONARY BIOLOGY

Mutational Signatures Indicative of Environmental Stress in Bacteria

(2014) Ram Maharjan et al.   MOLECULAR BIOLOGY AND EVOLUTION

Combating Evolution to Fight Disease

(2014) S. M. Rosenberg et al.   SCIENCE

Break-Induced Replication Is a Source of Mutation Clusters Underlying Kataegis

(2014) Cynthia J. Sakofsky et al.   Cell Reports

β-lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity

(2013) A. Gutierrez et al.   Nature Communications

R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli

(2013) Hallie Wimberly et al.   Nature Communications

Deciphering Signatures of Mutational Processes Operative in Human Cancer

(2013) Ludmil B. Alexandrov et al.   Cell Reports

On the Mutational Topology of the Bacterial Genome

(2013) Patricia L. Foster et al.   G3-Genes Genomes Genetics

The Yeast Environmental Stress Response Regulates Mutagenesis Induced by Proteotoxic Stress

(2013) Erika Shor et al.   PLoS Genetics

Engineered proteins detect spontaneous DNA breakage in human and bacterial cells

(2013) Chandan Shee et al.   eLife

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

THE EVOLUTION OF STRESS-INDUCED HYPERMUTATION IN ASEXUAL POPULATIONS

(2012) Yoav Ram et al.   EVOLUTION

Transcriptional De-Repression and Mfd Are Mutagenic in Stressed Bacillus subtilis Cells

(2012) Holly Anne Martin et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions

(2012) Steven A. Roberts et al.   MOLECULAR CELL

Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy

(2012) Guangbo Chen et al.   NATURE

Evidence of non-random mutation rates suggests an evolutionary risk management strategy

(2012) Iñigo Martincorena et al.   NATURE

Rho-dependent transcription termination is essential to prevent excessive genome-wide R-loops in Escherichia coli

(2012) J. Krishna Leela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Mechanisms Produce Mutation Hotspots at DNA Breaks in Escherichia coli

(2012) Chandan Shee et al.   Cell Reports

Redox-Responsive Zinc Finger Fidelity Switch in Homing Endonuclease and Intron Promiscuity in Oxidative Stress

(2011) Justin B. Robbins et al.   CURRENT BIOLOGY

Variation in the mutation rate across mammalian genomes

(2011) Alan Hodgkinson et al.   NATURE REVIEWS GENETICS

Impact of a stress-inducible switch to mutagenic repair of DNA breaks on mutation in Escherichia coli

(2011) C. Shee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Chromosomal Structural Instability in a Subpopulation of Starving Escherichia coli Cells

(2011) Dongxu Lin et al.   PLoS Genetics

The RpoS-Mediated General Stress Response inEscherichia coli

(2010) Aurelia Battesti et al.   Annual Review of Microbiology

Separate DNA Pol II- and Pol IV-Dependent Pathways of Stress-Induced Mutation during Double-Strand-Break Repair in Escherichia coli Are Controlled by RpoS

(2010) R. L. Frisch et al.   JOURNAL OF BACTERIOLOGY

Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis

(2010) Michael A. Kohanski et al.   MOLECULAR CELL

The σE stress response is required for stress-induced mutation and amplification in Escherichia coli

(2010) Janet L. Gibson et al.   MOLECULAR MICROBIOLOGY

Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons

(2010) Valeria Specchia et al.   NATURE

DinB Upregulation Is the Sole Role of the SOS Response in Stress-Induced Mutagenesis in Escherichia coli

(2009) R. S. Galhardo et al.   GENETICS

Stress-Induced  -Lactam Antibiotic Resistance Mutation and Sequences of Stationary-Phase Mutations in the Escherichia coli Chromosome

(2009) J. F. Petrosino et al.   JOURNAL OF BACTERIOLOGY

Global Regulators Orchestrate Group II Intron Retromobility

(2009) Colin J. Coros et al.   MOLECULAR CELL

Mechanisms of change in gene copy number

(2009) P. J. Hastings et al.   NATURE REVIEWS GENETICS

A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation

(2009) P. J. Hastings et al.   PLoS Genetics