Article
Pediatrics
Joanna Yuet-ling Tung, Frederick Ka-wing Ho, Keith Tsz-suen Tung, Rosa Sze-man Wong, Wilfred Hing-sang Wong, Bik-chu Chow, Patrick Ip
Summary: The study found that one-third of obese students in junior primary school remained obese into adolescence. Baseline physical fitness level did not improve the predictive value for future obesity. Further research should investigate prognostic factors influencing the natural course of childhood obesity.
Article
Multidisciplinary Sciences
Yushu Wu, Chunyu Kit
Summary: This article introduces the features and establishment process of the Hong Kong Corpus of Chinese Sentence and Passage Reading (HKC), and shares eye movement data obtained through eye tracking measurements. The study found that factors such as visual complexity, word frequency, and reading scenario have significant impacts on eye movements, providing valuable resources for exploring eye movement control. By contrasting the different scenarios of single-sentence and passage reading, the research hopes to shed new light on the universal nature of reading and the unique characteristics of Chinese reading.
Article
Education & Educational Research
Daphnee Hui Lin Lee
Summary: This article examines the impact of social demographics and school culture on school collaborative culture. The results show that different school bandings have different school cultures, which have a negative impact on school collaborative culture. Likewise, individuals with different family backgrounds also have an influence on school culture. Therefore, school leaders can promote collaborative culture by developing leadership relations and professional development.
EDUCATIONAL MANAGEMENT ADMINISTRATION & LEADERSHIP
(2023)
Article
Public, Environmental & Occupational Health
Angela Chang, Peter Johannes Schulz, Wen Jiao, Matthew Tingchi Liu
Summary: This study examines the coverage of obesity and related diseases in digital news in Mainland China, Hong Kong, and Taiwan from 2010 to 2019. It finds an increasing attention to obesity-related news since 2016, with a focus on stress and tobacco as shared causative attributes. The study also reveals a strong link between obesity and cardiovascular diseases, indicating a higher link between cancer and obesity despite the focus on personal afflictions in the discourse.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2021)
Article
Clinical Neurology
Qiu-Ye Lan, Kate Ching-Ching Chan, Chun-Ting Au, Peggy Hiu-Ying Chan, Ngan Yin Chan, Yun Kwok Wing, Albert Martin Li, Hugh Simon Lam
Summary: This study aimed to evaluate the secular trends of sleep-wake patterns of preschool children in Hong Kong. It found a significant downward trend in sleep duration and a positive correlation between parental and children's sleep duration.
Article
Environmental Sciences
Jinjian Chen, Yiqian Zeng, Alexis K. H. Lau, Cui Guo, Xianglin Wei, Changqing Lin, Bo Huang, Xiang Qian Lao
Summary: A prospective cohort study in Hong Kong reveals that air pollution has detrimental effects on respiratory health, particularly in older male schoolchildren.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Public, Environmental & Occupational Health
Doris Y. P. Leung, Sau Fong Leung, Xue-Lin Zhang, Jia-Yin Ruan, Wing-Fai Yeung, Yim-Wah Mak
Summary: This study aimed to understand the prevalence of severe depressive symptoms and its association with factors at four levels (individual, relationship, school, and society) in a large sample of Hong Kong Chinese secondary school students. The study found that 7.4% of students had severe depressive symptoms, and 22 factors were significantly associated with these symptoms. The identification of these factors provides a knowledge basis for developing comprehensive preventive intervention programs.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Genetics & Heredity
Mullin Ho Chung Yu, Marcus Chun Yin Chan, Claudia Ching Yan Chung, Andrew Wang Tat Li, Chara Yin Wa Yip, Christopher Chun Yu Mak, Jeffrey Fong Ting Chau, Mianne Lee, Jasmine Lee Fong Fung, Mandy Ho Yin Tsang, Joshua Chun Ki Chan, Wilfred Hing Sang Wong, Jing Yang, William Chun Ming Chui, Patrick Ho Yu Chung, Wanling Yang, So Lun Lee, Godfrey Chi Fung Chan, Paul Kwong Hang Tam, Yu Lung Lau, Clara Sze Man Tang, Kit San Yeung, Brian Hon Yin Chung
Summary: This study examined pharmacogenomics in 1116 Hong Kong Chinese using exome sequencing data to identify actionable pharmacogenetic variants. Nearly all subjects carried at least one actionable pharmacogenetic variant, while a majority also harbored at least one rare, deleterious pharmacogenetic variant. Prescription data analysis revealed that 13.4% of the Hong Kong population were prescribed drugs with pharmacogenetic clinical guideline recommendations. The study demonstrates the feasibility of using exome sequencing for pharmacogenetic analysis and the potential of preemptive pharmacogenetic testing to support prescription decisions in the Hong Kong Chinese population.
Article
Pediatrics
Diya Dou, Daniel T. L. Shek
Summary: This study examined students' perceptions of the New Senior Secondary curriculum in Hong Kong, with a focus on their noncognitive development. The results showed that most students liked the curriculum and acknowledged its benefits in promoting their noncognitive skills. However, there were also substantial proportions of students who had relatively negative responses to some aspects of the curriculum.
FRONTIERS IN PEDIATRICS
(2022)
Article
Business, Finance
Shuangqi Li, Qi-an Chen
Summary: This study examines the effects of the Shanghai-Hong Kong Stock Connect and Shenzhen-Hong Kong Stock Connect on the relationships between the Mainland Chinese, Hong Kong, and U.S. stock markets. It finds that while the programs do not substantially enhance daily price co-movements, they significantly increase weekly price co-movements after the Shenzhen-Hong Kong Stock Connect.
INTERNATIONAL JOURNAL OF FINANCE & ECONOMICS
(2021)
Article
Public, Environmental & Occupational Health
Katherine Y. P. Sze, Eric K. P. Lee, Rufina H. W. Chan, Jean H. Kim
Summary: This study found that negative emotional eating is prevalent among female Chinese university students and not uncommon among male students. Management of negative emotional eating should be included as a component of university mental health promotion programmes in the region.
Article
Health Care Sciences & Services
Hang-Long Li, Jasper Tromp, Kanako Teramoto, Yi-Kei Tse, Si-Yeung Yu, Lok-Yee Lam, Kwan-Yu Li, Mei-zhen Wu, Qing-wen Ren, Pui-Fai Wong, Ching-Lung Cheung, Kelvin Kai-Wang To, Hung-Fat Tse, Carolyn S. P. Lam, Kai-Hang Yiu
Summary: This study examines the epidemiological trends and clinical features of infective endocarditis (IE) in Hong Kong. The incidence of IE remained unchanged between 2002 and 2019, but patients in 2019 were older and had more comorbidities. Surgery was associated with a significant reduction in 1-year all-cause mortality. Advanced age and comorbidities were identified as significant contributors to death.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2022)
Article
Multidisciplinary Sciences
Yetta Kwailing Wong, Christine Kong-Yan Tong, Ming Lui, Alan C-N Wong
Summary: This study found that perceptual expertise with words plays a crucial role in Chinese reading performance in developmental dyslexia, and suggests that perceptual training could be a potential remediation direction.
Article
Public, Environmental & Occupational Health
Zhengxing Xu, Min Chen, Yuntong Yao, Lisha Yu, Peijing Yan, Huijie Cui, Ping Li, Jiaqiang Liao, Ben Zhang, Yuqin Yao, Zhenmi Liu, Xia Jiang, Tao Liu, Chenghan Xiao
Summary: This study aimed to explore the relationship between sleep duration and obesity among Chinese Han people and Chinese ethnic minorities. The results showed that there was a significant association between sleep duration and BMI and waist circumference in Han people, but no association in ethnic minorities.
Article
Endocrinology & Metabolism
Juan Wen, Lijun Zhu, Chenbo Ji
Summary: During the COVID-19 school closures, childhood obesity prevalence increased while overweight prevalence decreased. The average increase in height was about 1 cm less compared to the same period in previous years, with no noteworthy difference in weight change observed.
INTERNATIONAL JOURNAL OF OBESITY
(2021)
Letter
Health Care Sciences & Services
Joshua Heng Tang, Yun Kwok Wing, Joey W. Y. Chan, Raymond S. K. Lo
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2023)
Article
Medicine, General & Internal
Sankar D. Navaneethan, Sophia Zoungas, M. Luiza Caramori, Juliana C. N. Chan, Hiddo J. L. Heerspink, Clint Hurst, Adrian Liew, Erin D. Michos, Wasiu A. Olowu, Tami Sadusky, Nikhil Tandon, Katherine R. Tuttle, Christoph Wanner, Katy G. Wilkens, Jonathan C. Craig, David J. Tunnicliffe, Marcello Tonelli, Michael Cheung, Amy Earley, Peter Rossing, Ian H. de Boer, Kamlesh Khunti
Summary: The KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease is an update of the 2020 guideline. The guideline was updated based on reviewing new evidence and using the GRADE approach to assess evidence and develop consensus practice points. The recommendations were updated in the areas of comprehensive care and glucose-lowering therapies, while recommendations in the areas of glycemic monitoring, lifestyle interventions, and management approaches remained unchanged.
ANNALS OF INTERNAL MEDICINE
(2023)
Letter
Medicine, General & Internal
Raymond Ngai Chiu Chan, Robert Ngai Fung Chan, Oscar Hou In Chou, Gary Tse, Sharen Lee
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2023)
Review
Cell Biology
Daiqi Liu, Xuyao Han, Zhiwei Zhang, Gary Tse, Qingmiao Shao, Tong Liu
Summary: Heat shock proteins (HSPs) are protective proteins that play a role in cell stress response. They have been found to protect cells and organs, especially the cardiovascular system, against harmful conditions. Recent research has focused on the role of HSPs in the remodeling of atrial fibrillation (AF), a common arrhythmia that can be life-threatening.
Article
Nutrition & Dietetics
Yingzhao Jin, Ho So, Ester Cerin, Anthony Barnett, Sumaira Mubarik, Kamal Hezam, Xiaoqi Feng, Ziyue Wang, Junjie Huang, Chenwen Zhong, Khezar Hayat, Fang Wang, Ai-Min Wu, Suowen Xu, Zhiyong Zou, Lee-Ling Lim, Jiao Cai, Yimeng Song, Lai-shan Tam, Dongze Wu
Summary: The disease burden attributable to metabolic risk factors is rapidly increasing in China, especially in older people. This study estimated the pattern and trend of six metabolic risk factors in China from 1990 to 2019, and compared the disease burden among G20 countries. The results showed that population aging continuously accelerates the metabolic risk factor driven disease burden in China.
FRONTIERS IN NUTRITION
(2023)
Article
Endocrinology & Metabolism
Carlin Chang, Jiandong Zhou, Oscar Hou In Chou, Justin Chan, Keith Sai Kit Leung, Teddy Tai Loy Lee, Wing Tak Wong, Abraham Ka Chung Wai, Tong Liu, Qingpeng Zhang, Sharen Lee, Gary Tse
Summary: This study evaluated the predictive value of neutrophil-to-lymphocyte ratio (NLR) for ischemic stroke and atrial fibrillation (AF) in patients with type 2 diabetes mellitus. The results showed that NLR was significantly associated with an increased risk of new-onset ischemic stroke and AF. NLR had predictive value for ischemic stroke but lower predictive value for AF in Chinese type 2 diabetes patients.
ENDOCRINOLOGY DIABETES & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Baoqi Fan, Cadmon K. P. Lim, Emily W. M. Poon, Eric S. H. Lau, Hongjiang Wu, Aimin Yang, Mai Shi, Claudia H. T. Tam, Samuel Y. S. Wong, Eric Kam-Pui Lee, Maggie H. T. Wang, Natural H. S. Chu, Risa Ozaki, Alice P. S. Kong, Elaine Chow, Ronald C. W. Ma, Andrea O. Y. Luk, Juliana C. N. Chan
Summary: This study examined the associations of GAD antibodies (GADA) and C-peptide (CP) with insulin initiation, glycemic responses, and severe hypoglycemia in Chinese patients with type 2 diabetes (T2D). The results showed that GADA+ and high CP were associated with early insulin initiation, while GADA+ and low CP increased the risk of severe hypoglycemia.
Article
Nutrition & Dietetics
Natural Chu, Tsz Yeung Chan, Yuen Kiu Chu, James Ling, Jie He, Kathy Leung, Ronald C. W. Ma, Juliana C. N. Chan, Elaine Chow
Summary: This study found that the dietary intake of minerals was negatively correlated with body fat in people with impaired glucose tolerance (IGT). People with obesity had lower daily consumption of iron, magnesium, and potassium compared to overweight and normal weight individuals. Higher dietary magnesium and potassium intake were associated with lower body fat in people with IGT. Inadequate dietary mineral intake may contribute to obesity and metabolic disorders independent of macronutrients and fiber consumption.
FRONTIERS IN NUTRITION
(2023)
Review
Cardiac & Cardiovascular Systems
Gary Tse, Quinncy Lee, Oscar Hou In Chou, Cheuk To Chung, Sharen Lee, Jeffrey Shi Kai Chan, Guoliang Li, Narinder Kaur, Leonardo Roever, Haipeng Liu, Tong Liu, Jiandong Zhou
Summary: Routinely collected electronic health records (EHRs) data provide valuable information for epidemiological studies, and the use of big data and artificial intelligence (AI) has rapidly increased in Hong Kong since 2015. The advantages of big data include generalizability, simultaneous determination of multiple outcomes, ease of cross-validation, analysis of numerous variables, analysis of static and dynamic variables, capturing non-linear and latent interactions, and enhancing prediction models with AI approaches.
CURRENT PROBLEMS IN CARDIOLOGY
(2024)
Article
Endocrinology & Metabolism
Johnny T. K. Cheung, Aimin Yang, Hongjiang Wu, Eric S. H. Lau, Alice P. S. Kong, Ronald C. W. Ma, Andrea O. Y. Luk, Juliana C. N. Chan, Elaine Chow
Summary: This study aimed to investigate whether early treatment intensification using dipeptidylpeptidase 4 inhibitors (DPP4i) delays insulin initiation in Chinese patients diagnosed with type 2 diabetes for less than 5 years. The results showed that early DPP4i intensification and low glycated haemoglobin (HbA1c) variability score (HVS) were associated with delayed insulin initiation.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Review
Biochemistry & Molecular Biology
Bonn Lee, Charlotte Edling, Shiraz Ahmad, Fiona E. N. Lebeau, Gary Tse, Kamalan Jeevaratnam
Summary: This study reviewed clinical and non-clinical literature on cardiovascular disease risks, electrocardiograms, neurocardiac lesions in Parkinson's disease, and fundamental electrophysiological studies. Pathological evidence suggests that the hearts of Parkinson's disease patients may undergo alpha-synucleinopathy. Future research is needed to integrate cardiac electrophysiology and pathological alterations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Endocrinology & Metabolism
Richard David Leslie, Ronald Ching Wan Ma, Paul W. Franks, Kristen J. Nadeau, Ewan R. Pearson, Maria Jose Redondo
Summary: This article discusses the heterogeneity of diabetes and proposes different models for disease management. It emphasizes the importance of precision medicine in defining disease risk and complications risk, which can lead to improved health outcomes and new therapeutic approaches.
LANCET DIABETES & ENDOCRINOLOGY
(2023)
Article
Health Care Sciences & Services
Si-Jing Chen, Shirley Xin Li, Ji-Hui Zhang, Siu Ping Lam, Mandy Wai Man Yu, Chi Ching Tsang, Alice Pik Shan Kong, Kate Ching Ching Chan, Albert Martin Li, Yun Kwok Wing, Ngan Yin Chan
Summary: Insufficient sleep negatively affects child development and neurocognitive abilities, highlighting the importance of interventions to promote sleep health in children. This study evaluated the effectiveness of a school-based sleep education program and found that while it improved parental sleep knowledge and behavioral outcomes in children, it did not significantly impact sleep-wake patterns and sleep problems.
Article
Endocrinology & Metabolism
Jonathan V. V. Mui, Lifang Li, Oscar Hou In Chou, Nida Azfar, Athena Lee, Jeremy Hui, Sharen Lee, Gary Tse, Jiandong Zhou
Summary: This study investigated the risk of new onset depression in patients with type 2 diabetes mellitus using sodium-glucose co-transporter 2 inhibitors (SGLT2Is) compared to dipeptidyl peptidase 4 inhibitors (DPP4Is). The findings suggest that SGLT2I use is associated with a significantly lower risk of depression compared to DPP4I use in these patients.
ACTA DIABETOLOGICA
(2023)
Review
Medicine, Research & Experimental
Laura M. Jacobsen, Jennifer L. Sherr, Elizabeth Considine, Angela Chen, Sarah M. Peeling, Margo Hulsmans, Sara Charleer, Marzhan Urazbayeva, Mustafa Tosur, Selma Alamarie, Maria J. Redondo, Korey K. Hood, Peter A. Gottlieb, Pieter Gillard, Jessie J. Wong, Irl B. Hirsch, Richard E. Pratley, Lori M. Laffel, Chantal Mathieu, I ADA EASD PMD
Summary: Jacobsen, Sherr et al. evaluate the utility of novel technologies in the treatment of type 1 diabetes. Their systematic review finds technologies such as continuous glucose monitoring, insulin pumps, and decision support tools improve important measures (e.g., HbA1c, time in range, quality of life) allowing precision-directed uptake of technology.
COMMUNICATIONS MEDICINE
(2023)