Article
Engineering, Chemical
Tugba Yarbas, Alime Citak
Summary: Pure and boron-containing B-SBA-15 mesoporous materials were synthesized and characterized. The surface properties of the samples were found to be influenced by the boron content and temperature, with higher boron content resulting in more acidic surface.
INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES
(2022)
Article
Chemistry, Inorganic & Nuclear
Selvakumari Ulagesan, Madhappan Santhamoorthy, Thi Phan Vy Phan, Krishnapandi Alagumalai, Kokila Thirupathi, Seong-Cheol Kim, Taek-Jeong Nam, Youn-Hee Choi
Summary: In this study, a mesoporous silica material containing amidoxime ligand groups was successfully synthesized through surface modification. The resulting SBA-15@AMI NPs exhibited a high concentration of amidoxime ligands on the surface, making them suitable for pH-responsive drug delivery applications in cancer therapy.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Juan Gonzalez, Eduardo Perez, Marzena Pepczynska, Lourdes Calvo, Albertina Cabanas
Summary: Naproxen was impregnated into mesoporous SiO2 SBA-15 using the Supercritical Solution Impregnation (SSI) technique. The percentage of naproxen impregnated decreased with increasing CO2 density and with the addition of ethanol, ethyl acetate or menthol. The impregnated naproxen on SiO2 became amorphous and showed interaction with SiO2 support. Release tests showed a sustained release system with a slower rate compared to pure naproxen due to the interaction and diffusion of the drug.
JOURNAL OF CO2 UTILIZATION
(2023)
Article
Chemistry, Physical
Andrea Huerta, Maria Jose Torralvo, Maria Jose Tenorio, Eduardo Perez, Jonathan Bermudez, Lourdes Calvo, Albertina Cabanas
Summary: In this study, Au/SiO2 SBA-15 materials were prepared using supercritical CO2 and wet impregnation methods. The materials prepared on the highest thiol grafting density support showed a homogeneous distribution of small-sized Au nanoparticles, while the materials prepared on the low thiol grafting density support showed a bimodal particle size distribution.
JOURNAL OF SUPERCRITICAL FLUIDS
(2022)
Article
Chemistry, Multidisciplinary
Qingshuang Wang, Yurui Cui, Wei Ai, Siqi Li, Zhe Zhang, Xiangru Feng
Summary: In this study, ordered mesoporous silica SBA-15 and amino group-decorated SBA-15 (NH2-SBA-15) were synthesized for the delivery of the antibiotic amoxicillin. Both nanocomposites showed high drug loading capacity, continuous drug release, and significant antibacterial activity against E. coli and S. aureus. Subcutaneous injection of amoxicillin-loaded nanocomposites effectively alleviated S. aureus skin infection in mice and improved wound recovery. The SBA-15-based drug carrier reduces the need for frequent administration and offers a promising approach for the controlled and sustained release of antibiotics for skin infections.
NEW JOURNAL OF CHEMISTRY
(2023)
Review
Immunology
Sheikh Mohammad Fazle Akbar, Mamun Al Mahtab, Ferdousi Begum, Shaikh A. Shahed Hossain, Sukumar Sarker, Ananta Shrestha, Md Sakirul Islam Khan, Osamu Yoshida, Yoichi Hiasa
Summary: The article discusses strengthening and expanding the Hepatitis B vaccination program in SEARO countries with an emphasis on HepB and HepB-BD programs.
Review
Microbiology
Nicanor Austriaco
Summary: Currently, orally delivered vaccines have advantages over injected vaccines, but approved oral vaccines are limited to diseases that affect the gastrointestinal tract or crucial life cycle stages in the gut. All approved oral vaccines involve live-attenuated or inactivated pathogens. This mini-review explores the potential and challenges of yeast oral vaccine delivery systems for animal and human infectious diseases.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Engineering, Environmental
Jiantao Liang, Weirui Chen, Gaozu Liao, Jing Wang, Xipeng Wei, Yiming Tang, Xukai Li, Laisheng Li
Summary: A facile hydrothermal method was proposed to regulate the pore structure and introduce Ce-based Lewis sites within Ce-SBA-15, named as Ce-SBA-U. The mesoporous size of Ce-SBA-U could be enlarged by urea dosage, facilitating the mass transfer of ozone and its activation on Ce(III)-based Lewis sites. The Ce-SBA-U/O3 process achieved high removal rates of clofibric acid (CA) and TOC, indicating its superior performance compared to sole ozonation and Ce-SBA-15/O3 processes.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Chemistry, Applied
Ishani Bhat, R. J. Madhura, Murali Badanthadka, Bangera Sheshappa Mamatha
Summary: Cow-ghee enhances the intestinal absorption of lutein and improves its oral bioavailability, potentially serving as a delivery vehicle for the compound. This study is the first to report the influence of saturated fatty acids on the oral bioavailability of lutein in an in-vivo system.
Article
Chemistry, Applied
Silvia Leccese, Thomas Onfroy, Adjele Wilson, Diana Kirilovsky, Sandra Casale, Saremble Guira, Mohamed Selmane, Claude Jolivalt, Alberto Mezzetti
Summary: This study focuses on the immobilization of the photoactive Orange Carotenoid Protein (OCP) on mesoporous silica nanoparticles and investigates its structural characterization. The results highlight the enhanced immobilization of OCP by pre-photoactivation, leading to photochromic nanoparticles. The study also explores the possibility of releasing OCP from the nanoparticles and suggests potential applications in nanoscale optical devices and antioxidant drug delivery.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Immunology
Jing Peng, Xueying Yao, Chunyan Yuan, Xiaoli Liu, Renxiang Xia, Jian He, Rui Li, Yunqing Yao
Summary: This study investigated the potential mechanism and therapeutic potential of hepatitis B vaccine immunotherapy for occult hepatitis B virus infection (OBI) patients. The results showed that hepatitis B vaccine significantly increased the levels of hepatitis B surface antibodies in patients and had a significant impact on the number of peripheral blood B lymphocytes and CD8(+) T lymphocytes.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Pharmacology & Pharmacy
Pedro Gonzalez-Cruz, Harvinder Singh Gill
Summary: Oral vaccination using particles for antigen protection and delivery is a promising field, but faces challenges in formulation characteristics and dosing schedules. Standardizing vaccination parameters and utilizing adjuvants to enhance immune responses are crucial for improving oral vaccines in the future.
EXPERT OPINION ON DRUG DELIVERY
(2021)
Article
Biotechnology & Applied Microbiology
Yang Zhou, Ying Su, Rui Yan, Xuewen Tang, Xuan Deng, Yao Zhu, Xiaoping Xu, Hanqing He
Summary: This study aimed to determine the level of viral hepatitis knowledge and self-awareness among HBsAg positive individuals in Zhejiang Province, China. A cross-sectional survey was conducted among 3,626 participants aged 15-69 years using 10 knowledge questions. The knowledge rate of viral hepatitis among the general population was 52.34% and majority of participants had adequate knowledge.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Huiqing Liu, Lili Li, Yali Li, Minmin Liu, Yarong Song, Feng Ding, Xiaoshu Zhang, Jie Li
Summary: This study aimed to investigate the effects of delivery and feeding mode on infants' immune response to hepatitis B vaccine. The results showed that natural vaginal delivery and breastfeeding contribute to enhancing the infant's immune response to the vaccine.
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY
(2023)
Article
Materials Science, Ceramics
Thomas Cadenbach, Maria J. Benitez, Sofia Andrade Tirado, Valeria Ochoa-Herrera, Alexis Debut, Karla Vizuete
Summary: BiFeO3 nanomaterials have attracted much interest as effective visible-light photocatalysts for water splitting and organic pollutant degradation due to their narrow band gap energies. The use of GdxBi1-xFeO3@SBA-15 nanocomposites can achieve high removal efficiency of the organic dye Rhodamine B, with the 10 vol% Gd0.05Bi0.95FeO3@SBA-15 sample showing the best performance. The synergistic adsorption enhanced photocatalytic degradation process contributes to the superior efficiencies of the nanocomposites over their parent compounds.
CERAMICS INTERNATIONAL
(2021)
Review
Chemistry, Multidisciplinary
Marcia Carvalho de Abreu Fantini, Cristiano Luis Pinto Oliveira, Jose Luiz de Souza Lopes, Tereza da Silva Martins, Milena Apetito Akamatsu, Aryene Goes Trezena, Milene Tino-De-Franco, Viviane Fongaro Botosso, Osvaldo Augusto Brazil Esteves Sant'Anna, Nikolay Kardjilov, Martin Kjaerulf Rasmussen, Heloisa Nunes Bordallo
Summary: This article summarizes the progress made in oral vaccine formulations using porous silica matrices for antigen encapsulation. These vaccine vehicles effectively protect the antigens from stomach acid and enhance immunity. The research conducted at the Butantan Institute in Brazil is highlighted, with a focus on optimizing antigen encapsulation yield and distribution inside the silica matrix. Structural characterization and modeling were performed using various techniques, revealing the efficacy and stability of the proposed oral immunogenic complex.
Article
Physics, Condensed Matter
C. L. P. Oliveira, J. L. S. Lopes, O. A. Sant'Anna, V. F. Botosso, H. N. Bordallo, M. C. A. Fantini
Summary: Ordered mesoporous silica is an efficient oral adjuvant for delivering a variety of antigens. It has shown promising results in inducing immune response for different antigens without toxicity. Physics methods have been used to characterize the material and determine the ideal antigen load and release rate for developing proper oral vaccines.
JOURNAL OF PHYSICS-CONDENSED MATTER
(2022)
Article
Chemistry, Analytical
Karla R. Castro, Grazielle O. Setti, Tassia R. de Oliveira, Monica J. Rodrigues-Jesus, Viviane F. Botosso, Ana P. Perini de Araujo, Edson L. Durigon, Luis C. S. Ferreira, Ronaldo C. Faria
Summary: An electrochemical immunoassay using magnetic beads and enzyme-labeled antibodies was developed for the detection of anti-ZIKV antibodies. The method showed high efficiency in detecting anti-ZIKV antibodies in serum samples, offering promising perspectives for the development of fast, simple, and affordable point-of-care diagnosis devices for ZIKV.
Article
Chemistry, Physical
Hugo Laval, Alexandre Holmes, Matthew A. A. Marcus, Benjamin Watts, Gwenael Bonfante, Marc Schmutz, Elise Deniau, Robin Szymanski, Christine Lartigau-Dagron, Xiaoxue Xu, Julie M. M. Cairney, Kazuhiko Hirakawa, Fumiyasu Awai, Takaya Kubo, Guillaume Wantz, Antoine Bousquet, Natalie P. P. Holmes, Sylvain Chambon
Summary: Efficient organic photovoltaic devices fabricated from water-based colloidal dispersions with donor:acceptor composite nanoparticles achieving up to 9.98% power conversion efficiency (PCE) are reported. The high efficiency is attributed to morphology control by surface energy matching between the donor and the acceptor materials. The narrow gap between water-based inks and organic solvent-based inks is promising for the development of eco-friendly processing and fabrication of organic photovoltaics.
ADVANCED ENERGY MATERIALS
(2023)
Article
Chemistry, Organic
Cecilie Hogfeldt Jessen, Jesper Bendix, Theis Brock Nannestad, Heloisa Bordallo, Martin Jaeger Pedersen, Christian Marcus Pedersen, Mikael Bols
Summary: Carbon dioxide (CO2) emissions from industrial processes, power generation, and transportation contribute significantly to global warming and climate change. Carbon capture and storage (CCS) technologies are essential to reduce these emissions and mitigate the effects of climate change. Cyclodextrins (CDs) are studied as potential CO2 capture agents due to their unique molecular structures and high selectivity towards CO2. The binding efficiency of several cyclodextrins towards CO2 was investigated, and it was found that α-cyclodextrin with CO2 has a 1:1 stoichiometry. Additionally, per-O-methyl α-cyclodextrin showed the highest CO2 affinity with a binding constant (Kg) of 0.18-1.2 bar-1 (7-35 M-1).
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Nicolas P. L. Magnard, Andrea Kirsch, Mads R. V. Jorgensen, Innokenty Kantor, Daniel R. Sorensen, Simo Huotari, Svemir Rudic, Heloisa N. Bordallo, Kirsten M. O. Jensen
Summary: Manganesedioxide is a promising material for energy storage and conversion due to its rich electrochemistry and wide polymorphism. This study investigates the influence of hydrothermal synthesis parameters on the amount and type of H-related defects in γ-MnO2 nanoparticles. The results show that synthesis temperature and time independently affect the two types of defects, and the defect density varies from particle core to surface.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Xiangyin Tan, Barbara Bianca Gerbelli, Marcia Carvalho de Abreu Fantini, Cristiano Luis Pinto Oliveira, Heloisa Nunes Bordallo, Pedro Leonidas Oseliero Filho
Summary: A Monte Carlo method was used in analyzing SAXS data of SBA-15, resulting in the development of a new model called SBA-15+MC. This model allows for the retrieval of mesopore size distribution and shows improved performance compared to existing models. The strategies presented in this study can be applied to the analysis of other mesoporous materials as well.
JOURNAL OF APPLIED CRYSTALLOGRAPHY
(2023)
Article
Chemistry, Multidisciplinary
C. R. R. C. Lima, R. J. S. Lima, A. C. C. Bandeira, R. A. A. Couto, M. V. R. Velasco, H. N. Bordallo, C. L. P. Oliveira
Summary: This study investigated the effect of acid straightening on the morphology and ultrastructure of Caucasian hair using complementary experimental methods. The results showed that acid straightening changed the structure of the hair and modified its physicochemical and mechanical properties. The findings of this study are important for evaluating the action mode and efficiency of cosmetic treatments.
JOURNAL OF APPLIED CRYSTALLOGRAPHY
(2023)
Article
Materials Science, Multidisciplinary
Marwa Faisal, Marija Zmiric, Ngoc Quynh Nhu Kim, Sander Bruun, Loredana Mariniello, Michela Famiglietti, Heloisa N. Bordallo, Jacob Judas Kain Kirkensgaard, Bodil Jorgensen, Peter Ulvskov, Kim Henrik Hebelstrup, Andreas Blennow
Summary: Starch-based bioplastics show promise as an alternative to conventional plastics, but their mechanical strength and barrier properties have limitations. This study explores the use of nanocellulose as a reinforcing agent to address these challenges. The results demonstrate that both cellulose nanofibers (CNF) and cellulose nanocrystals (CNC) enhance the properties of the bioplastic films, with CNF having a more pronounced effect. The incorporation of nanocellulose also improves the transparency and thermal stability of the films.
Article
Chemistry, Multidisciplinary
Vera Tchakalova, Cristiano Luis Pinto Oliveira, Antonio Martins Figueiredo Neto
Summary: A new lyotropic, fragranced, viscoelastic fluid with a complex structure is obtained from fragranced microemulsions by adding a fatty acid. The formation of anisotropically shaped and highly oriented micelles in aqueous solution is achieved by nonhomogeneous mixing of an appropriate nonionic surfactant, a fatty acid, and a fragrance oil. The viscosity and nano- and microstructures of the fluid are controlled by the balance of fatty acids and fragrance molecules, which behave as a cosurfactant and segregate in the micelles. X-ray scattering and rheological methods characterize the transition from isotropic microemulsion to a more structured viscoelastic solution. With the ability to solubilize and retain fragrance, this complex structured fluid can be used as a 2-in-1 fragrance-solubilizing liquid product compatible with various consumer products for home and body care.
Article
Chemistry, Multidisciplinary
Cecilie Hogfeldt Jessen, Jesper Bendix, Theis Brock Nannestad, Heloisa N. N. Bordallo, Martin Jaeger Pedersen, Christian Marcus Pedersen, Mikael Bols
Summary: α-cyclodextrin dissolved in water forms a 1:1 complex with methane, yielding crystals with a maximum yield of 57%. The binding constant is K-a=21 (±1.0) M-1. 3(A),6(A),3(D),6(D)-dianhydro-α-cyclodextrin, which has a smaller cavity than α-cyclodextrin, binds methane three times better with a binding constant of K-a=75 (±25) M-1.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Ingemar Persson, Hugo Laval, Sylvain Chambon, Gwenael Bonfante, Kazuhiko Hirakawa, Guillaume Wantz, Benjamin Watts, Matthew A. A. Marcus, Xiaoxue Xu, Lei Ying, Girish Lakhwani, Mats R. R. Andersson, Julie M. M. Cairney, Natalie P. P. Holmes
Summary: In this study, we achieved sub-4 nm mapping of donor : acceptor nanoparticle composition in eco-friendly colloidal dispersions for organic electronics using low energy scanning transmission electron microscopy (STEM) energy dispersive X-ray spectroscopy (EDX) mapping. We utilized unique fingerprint elements (Si and S) to differentiate donor from acceptor material in each blend system. Synchrotron-based scanning transmission X-ray microscopy (STXM) was also demonstrated as a superior chemical contrast technique for mapping organic donor : acceptor morphology. The sub-4 nm mapping technology holds great promise for optimizing organic semiconductor blends in various applications.
Article
Chemistry, Multidisciplinary
Raphael F. Moral, Antonio A. Malfatti-Gasperini, Luiz G. Bonato, Brener R. C. Vale, Andre F. V. Fonseca, Lazaro A. Padilha, Cristiano L. P. Oliveira, Ana F. Nogueira
Summary: Perovskite nanocrystal superlattices and nanoplate self-assembly in solvents have significant impact on optical properties. The formation of nanoplate stacks can be induced by adjusting the nanoplate concentration and colloidal suspension viscosity. The degree of aggregation of perovskite nanoplates shows a positive correlation with the solvent viscosity. This self-assembly has important implications for Forster resonant energy transfer (FRET) in perovskite nanoplates.
MATERIALS HORIZONS
(2023)
Review
Medicine, General & Internal
Murillo L. Martins, Heloisa N. Bordallo, Eugene Mamontov
Summary: The severity of cancer statistics worldwide and the complexity of cancer cell behavior necessitate contributions from multidisciplinary research. Materials science has become a powerful tool in supporting biological research and understanding the behavior of cancer cells. In recent years, experimental works using Quasielastic neutron scattering (QENS) have shed new light on the role of water molecules in tumor cells and their response to external factors, particularly chemotherapy drugs.
MEDICINA-LITHUANIA
(2022)