Nrf2 signaling and autophagy are complementary in protecting lipopolysaccharide/d-galactosamine-induced acute liver injury by licochalcone A

NF-κB and Nrf2 pathways contribute to the protective effect of Licochalcone A on dextran sulphate sodium-induced ulcerative colitis in mice

(2018) Dongyu Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Glycycoumarin protects mice against acetaminophen-induced liver injury predominantly via activating sustained autophagy

(2018) Mingzhu Yan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Oxyresveratrol prevents lipopolysaccharide/ d -galactosamine-induced acute liver injury in mice

(2018) Ya-Nan Jia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

AMP-activated protein kinase agonist N6-(3-hydroxyphenyl)adenosine protects against fulminant hepatitis by suppressing inflammation and apoptosis

(2018) Jin Li et al.   Cell Death & Disease

Licochalcone A Upregulates Nrf2 Antioxidant Pathway and Thereby Alleviates Acetaminophen-Induced Hepatotoxicity

(2018) Hongming Lv et al.   Frontiers in Pharmacology

AMPK-dependent and independent actions of P2X7 in regulation of mitochondrial and lysosomal functions in microglia

(2018) Ponarulselvam Sekar et al.   Cell Communication and Signaling

Asiatic Acid Exhibits Anti-inflammatory and Antioxidant Activities against Lipopolysaccharide and d-Galactosamine-Induced Fulminant Hepatic Failure

(2017) Hongming Lv et al.   Frontiers in Immunology

Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis

(2017) Hongming Lv et al.   Redox Biology

Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice

(2016) Jihye Han et al.   Autophagy

Knockdown of FSTL1 inhibits oxLDL-induced inflammation responses through the TLR4/MyD88/NF-κB and MAPK pathway

(2016) Junxia Guo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway

(2016) Hong Yao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury in mice by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation

(2016) Xingkai Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice

(2016) Hong-Min Ni et al.   JOURNAL OF HEPATOLOGY

Nobiletin attenuates lipopolysaccharide/D-galactosamine-induced liver injury in mice by activating the Nrf2 antioxidant pathway and subsequently inhibiting NF-κB-mediated cytokine production

(2016) Zhenxing He et al.   Molecular Medicine Reports

Inhibition of glycogen synthase kinase 3β promotes autophagy to protect mice from acute liver failure mediated by peroxisome proliferator-activated receptor α

(2016) F Ren et al.   Cell Death & Disease

Sesamin ameliorates lipopolysaccharide/d-galactosamine-induced fulminant hepatic failure by suppression of Toll-like receptor 4 signaling in mice

(2015) Li Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neohesperidin dihydrochalcone down-regulates MyD88-dependent and -independent signaling by inhibiting endotoxin-induced trafficking of TLR4 to lipid rafts

(2015) Xiaomin Xia et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lico A Enhances Nrf2-Mediated Defense Mechanisms againstt-BHP-Induced Oxidative Stress and Cell Death via Akt and ERK Activation in RAW 264.7 Cells

(2015) Hongming Lv et al.   Oxidative Medicine and Cellular Longevity

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

CK2 Is Acting Upstream of MEK3/6 as a Part of the Signal Control of ERK1/2 and p38 MAPK during Keratinocytes Autocrine Differentiation

(2015) Antonia R. Isaeva et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES

TRPM2 channels mediate acetaminophen-induced liver damage

(2014) E. Kheradpezhouh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peroxisome proliferator-activated receptor α activation attenuates the inflammatory response to protect the liver from acute failure by promoting the autophagy pathway

(2014) M Jiao et al.   Cell Death & Disease

Cystathionine γ-Lyase Deficiency Protects Mice from Galactosamine/Lipopolysaccharide-Induced Acute Liver Failure

(2013) Kazuhiro Shirozu et al.   ANTIOXIDANTS & REDOX SIGNALING

NLRP3 inflammasome activation in d-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1

(2013) Seok-Joo Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Induction of autophagy, a promising approach for treating liver injury

(2013) Wen-Xing Ding   HEPATOLOGY

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

(2013) Amina A. Negash et al.   PLoS Pathogens

Licochalcone A Inhibits Lipopolysaccharide-Induced Inflammatory Response in Vitro and in Vivo

(2012) Xiao Chu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts

(2011) Hartmut Jaeschke   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Resolution of inflammation-related apoptotic processes by the synthetic tellurium compound, AS101 following liver injury

(2009) Miri Brodsky et al.   JOURNAL OF HEPATOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY