期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 60, 期 8, 页码 5059-5063出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00928-16
关键词
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资金
- NIH [R01AI091787]
- University of Florida Foundation and departmental funds
The apicomplexan parasites that cause malaria and babesiosis invade and proliferate within erythrocytes. To assess the potential for common antiparasitic treatments, we measured the sensitivities of multiple species of Plasmodium and Babesia parasites to the chemically diverse collection of antimalarial compounds in the Malaria Box library. We observed that these parasites share sensitivities to a large fraction of the same inhibitors and we identified compounds with strong babesiacidal activity.
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