Intracellular Notch1 Signaling in Cancer-Associated Fibroblasts Dictates the Plasticity and Stemness of Melanoma Stem/Initiating Cells

Notch1-WISP-1 axis determines the regulatory role of mesenchymal stem cell-derived stromal fibroblasts in melanoma metastasis

(2016) Hongwei Shao et al.   Oncotarget

Melanoma Cancer Stem Cells: Markers and Functions

(2016) Giorgio Parmiani   Cancers

Cancer stem cells and the tumor microenvironment: interplay in tumor heterogeneity

(2015) Adriana Albini et al.   CONNECTIVE TISSUE RESEARCH

Melanoma

(2015) Dirk Schadendorf et al.   Nature Reviews Disease Primers

Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion

(2015) Hongwei Shao et al.   PLoS One

Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling

(2014) Wan-Jiun Chen et al.   Nature Communications

Testing the cancer stem cell hypothesis in melanoma: The clinics will tell

(2012) Olga Shakhova et al.   CANCER LETTERS

CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells

(2012) A. Tsuyada et al.   CANCER RESEARCH

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

(2012) Valbona Luga et al.   CELL

Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterization

(2012) Virginia Tirino et al.   FASEB JOURNAL

Inhibition of Fibroblast Growth by Notch1 Signaling Is Mediated by Induction of Wnt11-Dependent WISP-1

(2012) Zhao-Jun Liu et al.   PLoS One

Human CD271-Positive Melanoma Stem Cells Associated with Metastasis Establish Tumor Heterogeneity and Long-term Growth

(2011) G. Civenni et al.   CANCER RESEARCH

Activation of Notch1 signaling in stromal fibroblasts inhibits melanoma growth by upregulating WISP-1

(2011) H Shao et al.   ONCOGENE

Isolation of tumorigenic circulating melanoma cells

(2010) Jie Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification and validation of Notch pathway activating compounds through a novel high-throughput screening method

(2010) Scott N. Pinchot et al.   CANCER

Reciprocal Activation of Prostate Cancer Cells and Cancer-Associated Fibroblasts Stimulates Epithelial-Mesenchymal Transition and Cancer Stemness

(2010) E. Giannoni et al.   CANCER RESEARCH

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

(2010) Alexander D. Boiko et al.   NATURE

Active Notch1 Confers a Transformed Phenotype to Primary Human Melanocytes

(2009) Chelsea C. Pinnix et al.   CANCER RESEARCH

Melanoma-initiating cells: a compass needed

(2009) Yosef Refaeli et al.   EMBO REPORTS

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

(2009) Erika L. Spaeth et al.   PLoS One

Direct Evidence of Mesenchymal Stem Cell Tropism for Tumor and Wounding Microenvironments Using In Vivo Bioluminescent Imaging

(2009) Shannon Kidd et al.   STEM CELLS

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE

Molecular Basis of Metastasis

(2008) Anne C. Chiang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7

(2008) Y Ishikawa et al.   ONCOGENE