Article
Chemistry, Analytical
Yaxing Xie, Guoming Xie, Jinshan Yuan, Jianhong Zhang, Yujun Yang, Yuan Yao, You Wu, Dan Bai, Kena Chen, Baiying Li, Lin Song, Hui Chen
Summary: A novel fluorescence biosensor based on double-stranded DNA branch migration-induced hybridization chain reaction (HCR) and DNAzyme feedback circuit was constructed for sensitive detection of Pseudomonas aeruginosa (P. aeruginosa). The biosensor showed promising clinical application potential with a wide linearity range of detection and a low limit of detection, without the need for protein enzymes and complex signal amplification procedures.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Na Ying, Yuan Wang, Xuefeng Song, Liguo Yang, Bo Qin, Yanqing Wu, Wenhong Fang
Summary: A new detection assay for Vibrio parahaemolyticus was introduced, utilizing aptamer combined with magnetic nanoparticles, hybridization chain reaction, and lateral flow nucleotide biosensor. It showed high specificity and fast detection time, making it suitable for low-resource laboratories or districts.
Article
Chemistry, Analytical
Yongjun Bian, Mengwei Li, Zhaojie Wu, Jian Weng, Ru Zeng, Liping Sun
Summary: Researchers have developed an ultrasensitive fluorescent biosensor using sporopollenin capsules as a substrate for isothermal amplification. This biosensor can detect miRNA with a low detection limit and a wide linear range, and it shows high selectivity and minimal interference from serum proteins.
Article
Chemistry, Analytical
Zheng Wei Wong, Siu Yee New
Summary: A fluorescence biosensor based on hybridisation chain reaction amplification coupled with silver nanoclusters has been developed for nucleic acid detection, providing a reliable and low risk method for detecting target DNA.
Article
Food Science & Technology
Jorge Garcia-Hernandez, Manuel Hernandez, Yolanda Moreno
Summary: Vibrio parahaemolyticus is a human food-borne pathogen capable of entering the food chain and acquiring a viable but non-cultivable state undetectable by traditional methods. The DVC-FISH technique can detect microorganisms presenting VBNC forms in complex samples. Results showed a significant logarithmic decrease of V. parahaemolyticus at low temperatures, while rapid proliferation occurred at 22 degrees Celsius.
Article
Food Science & Technology
Yuan-qing Hu, Wan-ying Wang, Turmidzi Fath, Feng-xia Li, Lin-fang Fang, Zan-hu Zhou, Dan-feng Zhang
Summary: In this study, a PMA-mPCR assay was developed for accurately screening viable vibrios in aquatic foods. The assay exhibited 100% specificity and maintained its sensitivity after PMA treatment. The results showed that the assay could detect viable V. parahaemolyticus, V. alginolyticus, and V. cholerae as low as 1.0 x 102 CFU/mL after 10 hours of enrichment. The practical application of the assay using 453 actual samples also demonstrated its accuracy in screening target vibrios in seafood.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Jinshan Yuan, Guoming Xie, Junjie Li, Yaxing Xie, Yuan Yao, Jianhong Zhang, Yulei Hou, Hui Chen
Summary: A fluorescent sensing platform was developed for the simple and sensitive monitoring of vancomycin, using an allosteric probe that undergoes a conformational change in the presence of vancomycin. This platform has the potential to support therapeutic drug monitoring of vancomycin, promoting the rational use of antibiotics in clinics.
ANALYTICA CHIMICA ACTA
(2023)
Article
Food Science & Technology
Monica Campas, Sandra Leonardo, Ainoa Ferre-Gode, Asif A. Chowdhury, Anna Toldra, Karl B. Andree, Ana Roque
Summary: Vibrio parahaemolyticus is a dominant cause of foodborne infections and can accumulate in shellfish. A duplex electrochemical biosensor was developed to detect the tdh and trh genes of V. parahaemolyticus in oysters, providing a quick and specific method for monitoring this pathogen.
Article
Chemistry, Analytical
Riham Zayani, Amal Rabti, Sami Ben Aoun, Noureddine Raouafi
Summary: The study introduces a novel method for sensitive detection of miRNAs levels using a dual signal readout system involving competitive hybridization of miR-21 target and its biotinylated analog. The bioplatform demonstrates low detection limits, wide linear calibration range, excellent selectivity towards non-complementary miRs, and acceptable distinction with single nucleotide mismatched sequences. Furthermore, the method was successfully used to determine miR-21 expression levels in blood sera from breast cancer patients.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Food Science & Technology
Xinrui Lv, Weiwei Cao, Huang Zhang, Yilin Zhang, Lei Shi, Lei Ye
Summary: A system combining chemically enhanced CRISPR and RAA technologies was established for detecting V. parahaemolyticus in seafood, showing rapid, accurate detection with no cross-reactivity.
Article
Chemistry, Analytical
Wenhai Wang, Shu Xiao, Mengli Zeng, Hongzhen Xie, Ning Gan
Summary: Rapid and accurate detection of Vibrio parahaemolyticus (VP) is crucial for preventing the spread of foodborne illnesses. A dual-mode colorimetric-electrochemical biosensor was developed for the rapid and sensitive detection of VP. The biosensor achieved an accuracy of 88.7%, higher than that of single-mode assays (81.1%). It has the potential to facilitate effective on-site detection of pathogens in shrimp samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Review
Chemistry, Analytical
Hang Li, Xuechen Wang, Shengnan Wei, Chao Zhao, Xiuling Song, Kun Xu, Juan Li, Bo Pang, Juan Wang
Summary: This article discusses the importance of hybridization chain reaction (HCR) in signal amplification and the latest research progress in its combined application with nanomaterials. Various new strategies in optical detection and their challenges are also explored.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Kuiyu Wang, Liebang Du, Liren Zhang, Xiliang Luo, Tao Yang, Hui Zeng
Summary: In this study, a modified-free microbial visual sensing platform was developed, which utilized a rapid sensing strategy and specific aptamers to achieve fast detection and analysis of target objects. It holds great potential in the fields of food pollutants detection, medical diagnosis, and environmental monitoring.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Dongyu Zhang, Han Lin, Le Chen, Yangbo Wu, Jianjun Xie, Xizhi Shi, Zhiyong Guo
Summary: A novel cluster-bomb type signal sensing and amplification strategy was proposed for low field nuclear magnetic resonance, and a magnetic biosensor was developed for ultrasensitive detection of Vibrio parahaemolyticus (VP). The biosensor utilized magnetic graphene oxide (MGO) and polystyrene (PS) pellets as capture and signal units, respectively, to capture and recognize VP. The dual signal amplification was achieved by increasing the amount and dispersity of signal labels. The biosensor showed satisfactory performance in terms of sensitivity, selectivity, stability, and reliability.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Dedi Futra, Ling Ling Tan, Su Yin Lee, Benchaporn Lertanantawong, Lee Yook Heng
Summary: An ultrasensitive electrochemical DNA biosensor was developed for rapid detection of Vibrio cholerae DNA in environmental samples. The biosensor utilized silica nanospheres functionalized with 3-aminopropyltriethoxysilane and gold nanoparticles for effective immobilization of the capture probe and acceleration of electron transfer. The targeted DNA sequence of V. cholerae was detected using a sandwich hybridization strategy with a pair of DNA probes and evaluated by differential pulse voltammetry.
Review
Chemistry, Analytical
Yongxin Li, Zewei Luo, Chuyan Zhang, Rui Sun, Chen Zhou, Chengjun Sun
Summary: Nucleic acids serve as genetic information carriers and powerful building blocks for signal amplification. Entropy-driven circuit (EDC) is considered a milestone in DNA circuits, featuring advantages of rapidness, simplicity, robustness, and modularity.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Yuting Li, Yuhan Yang, Zhijun Huang, Zewei Luo, Cheng Qian, Yinjun Li, Yixiang Duan
Summary: This study demonstrated the use of MIPDI for the first time to prepare low molecular weight chitosan, showing that the method is fast, efficient, and improves the antimicrobial properties of chitosan.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Chemistry, Multidisciplinary
Na Song, Yonghui Tian, Zewei Luo, Jianxiong Dai, Yan Liu, Yixiang Duan
Summary: This article summarizes the latest extraction techniques and analysis methods for the determination of BTEX and PAHs in soil, focusing on the potential and limitations of each method for different aromatic hydrocarbons.
Article
Chemistry, Analytical
Zhuanzhuan Wang, Haijing Guo, Zewei Luo, Yixiang Duan, Yaqiang Feng
Summary: In recent years, semiconducting polymer dots (Pdots) have attracted intense attention in ECL biosensing and imaging as environmentally friendly and high-brightness nanoemitters. However, the high ECL excitation potential of most available Pdots in the aqueous phase leads to poor selectivity in sample detection. This work demonstrates a simple and universal strategy to lower the trigger potential of Pdots based on electrochemiluminescence resonance energy transfer (ERET). The low potential Pdots showed excellent performance in glucose imaging detection.
ANALYTICAL CHEMISTRY
(2022)
Article
Biophysics
Yu Li, Xu Wang, Wei Ning, Enlai Yang, Yongxin Li, Zewei Luo, Yixiang Duan
Summary: The development of rapid and sensitive detection methods for pathogenic bacteria is crucial for disease therapy and prevention. In this study, a sandwich method based on omega-FOLSPR was constructed, demonstrating excellent selectivity and performance in detecting bacteria.
BIOSENSORS & BIOELECTRONICS
(2022)
Review
Chemistry, Analytical
Zewei Luo, Yongxin Li, Pei Zhang, Lu He, Yanting Feng, Yaqiang Feng, Cheng Qian, Yonghui Tian, Yixiang Duan
Summary: Catalytic hairpin assembly (CHA) is a promising molecular amplifier with advantages of high efficiency, flexible design, and mild reaction condition. In recent years, CHA has been coupled with multiple signal generation and signal transduction techniques to develop diversified fluorescent biosensors. The integration of emerging signal amplification techniques and other advanced technologies has further enhanced the application of CHA-based biosensors.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Zewei Luo, Yue Cheng, Lu He, Yanting Fen, Yonghui Tian, Zhenhua Chen, Yaqiang Feng, Yongxin Li, Wenjun Xie, Weiwei Huang, Jiantong Meng, Yu Li, Fan He, Xu Wang, Yixiang Duan
Summary: In this study, a localized surface plasmonic resonance (LSPR) biosensor based on omega-shaped fiber optic (omega-FO) was developed for dual assays of SARS-CoV-2 monitoring. The biosensor demonstrated real-time analysis and the ability to rapidly detect SARS-CoV-2 in both direct and sandwich assays. It achieved high accuracy in identifying healthy volunteers and COVID-19 patients, and also showed potential for detecting the virus on the surface of cold-chain foods.
ANALYTICAL CHEMISTRY
(2022)
Article
Medical Laboratory Technology
Xian Li, Xinxin Wen, Zewei Luo, Yonghui Tian, Cheng Qian, Jing Zhang, Rui Ling, Yixiang Duan
Summary: In this study, the urinary volatile organic compounds (VOCs) pattern of breast cancer patients was analyzed. Eight potential VOC biomarkers were identified and validated using the random forest algorithm, showing promising predictive ability for breast cancer diagnosis.
CLINICA CHIMICA ACTA
(2023)
Article
Optics
Fan He, Zewei Luo, Zhixi Wen, Haojie Huangfu, Yanting Feng, Xinyuan Qi, Yixiang Duan
Summary: The study demonstrates the use of a gold nanoparticle-decorated silver film (AuNPs-AgFM) as a coating in bent fiber optic surface plasmonic resonance (SPR) for integrated cytosensor and phototherapy. Optimization of parameters results in a high amplification sensitivity, wavelength sensitivity, and surface temperature for the designed SPR biosensor. This research holds significant importance for advancing the clinical application of fiber optics.
Article
Chemistry, Analytical
Yanting Feng, Zewei Luo, Juan Wu, Zhijun Huang, Lu He, Yaqiang Feng, Xian Li, Xudong Zhang, Yonghui Tian, Yongxin Li, Yixiang Duan
Summary: A new DNA logic platform coupled with multivariate statistical analysis was developed to classify seven different types of cancer cells. The platform demonstrated high specificity and sensitivity, generating strong dual fluorescent output signals in living cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Biophysics
Wei Ning, Chuyan Zhang, Ziyi Tian, Mengfan Wu, Zewei Luo, Shunming Hu, Hongzhi Pan, Yongxin Li
Summary: In this study, an omega-shaped fiber optic localized surface plasmon resonance (FO-LSPR) biosensor based on hybridization chain reaction (HCR) coupled with gold nanoparticles (AuNPs) was developed for simple and sensitive detection of cfDNA. The biosensor exhibited high sensitivity with a detection limit of 14.0 pM, making it a potential strategy for biomedical analysis and disease diagnosis.
BIOSENSORS & BIOELECTRONICS
(2023)
Review
Food Science & Technology
Ruonan Meng, Qiujin Zhu, Tingyu Long, Xuli He, Zewei Luo, Ronghui Gu, Wenzhong Wang, Ping Xiang
Summary: Food safety is a major global concern, especially in terms of heavy metal contamination in foods. Electrochemical sensors have emerged as a promising strategy for detecting heavy metals due to their flexibility, selectivity, and accuracy. This review highlights the advances in electrochemical sensors for heavy metal detection in foods, including the use of various modified electrodes. The review also discusses the challenges, applications, and prospects of electrochemical sensors in ensuring food safety.
Article
Engineering, Electrical & Electronic
Lingwei Zeng, Weiheng Kong, Sha Chen, Yu Rao, Mengfan Wu, Yixiang Duan, Qingwen Fan, Xu Wang, Zewei Luo
Summary: In this study, a hybrid deep learning model consisting of convolutional block attention module, convolutional neural network, and long short-term memory (CBAM-CNN-LSTM) was used for quantitative analysis in a portable LIBS system. The results showed that the CBAM-CNN-LSTM model outperformed the LR model, CNN model, and CNN-LSTM model, achieving higher accuracy and stability.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2023)
Article
Chemistry, Analytical
Xiaoyong Lu, Dan Li, Zewei Luo, Yixiang Duan
Summary: A fluorescent biosensor based on enzyme-involved catalytic hairpin assembly (CHA) was developed to detect both APE1 and miRNA-21, improving the accuracy of early-phase cancer diagnosis. The biosensor achieved a low limit of detection (LOD) and exhibited good selectivity and stability for the two biomarkers. Additionally, it acted as an AND logic gate.
Article
Chemistry, Analytical
Chuyan Zhang, Zewei Luo, Mengfan Wu, Wei Ning, Ziyi Tian, Yixiang Duan, Yongxin Li
Summary: A novel biosensor combining HCR and 3WJ-NEASA was developed for sensitive detection of food-borne bacteria, demonstrating broad application prospects in the field of food safety and environmental monitoring.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)