Vitexin alleviates interleukin‐1β‐induced inflammatory responses in chondrocytes from osteoarthritis patients: Involvement of HIF‐1α pathway

Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway

(2018) Jin Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

Baicalin suppresses IL-1β-induced expression of inflammatory cytokines via blocking NF-κB in human osteoarthritis chondrocytes and shows protective effect in mice osteoarthritis models

(2017) Chunhui Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Baicalin Inhibits Inflammatory Responses to Interleukin-1β Stimulation in Human Chondrocytes

(2017) Deguo Xing et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

TheBDKRB2 +9/-9 Polymorphisms Influence Pro-Inflammatory Cytokine Levels in Knee Osteoarthritis by Altering TLR-2 Expression: Clinical and in Vitro Studies

(2016) Shuo Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Tenuigenin Prevents IL-1β-induced Inflammation in Human Osteoarthritis Chondrocytes by Suppressing PI3K/AKT/NF-κB Signaling Pathway

(2016) Chunlei Wang et al.   INFLAMMATION

Neuroprotective effects of vitexin against isoflurane-induced neurotoxicity by targeting the TRPV1 and NR2B signaling pathways

(2016) Linlin Chen et al.   Molecular Medicine Reports

Expression of hypoxia-inducible factor-1α in synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis

(2016) Liming Qing et al.   Experimental and Therapeutic Medicine

Vitexin attenuates acute doxorubicin cardiotoxicity in rats via the suppression of oxidative stress, inflammation and apoptosis and the activation of FOXO3a

(2016) Zhan Sun et al.   Experimental and Therapeutic Medicine

Vitexin reduces hypoxia–ischemia neonatal brain injury by the inhibition of HIF-1alpha in a rat pup model

(2015) Jia-Wei Min et al.   NEUROPHARMACOLOGY

Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis

(2015) V. Silverwood et al.   OSTEOARTHRITIS AND CARTILAGE

Protective effect of vitexin compound B-1 against hypoxia/reoxygenation-induced injury in differentiated PC12 cells via NADPH oxidase inhibition

(2014) Zhong-Bao Yang et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Effects of hypoxia/ischemia on catabolic mediators of cartilage in a human chondrocyte, SW1353

(2013) Young Hoon Hong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ginsenoside Rb1 prevents interleukin-1 beta induced inflammation and apoptosis in human articular chondrocytes

(2013) Wendan Cheng et al.   INTERNATIONAL ORTHOPAEDICS

Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering

(2012) Elise Duval et al.   BIOMATERIALS

Regulation of hypoxia-inducible factor-1α (HIF-1α) expression by interleukin-1β (IL-1β), insulin-like growth factors I (IGF-I) and II (IGF-II) in human osteoarthritic chondrocytes

(2012) AR Sartori-Cintra et al.   Clinics

Interleukin-17A promotes rheumatoid arthritis synoviocytes migration and invasion under hypoxia by increasing MMP2 and MMP9 expression through NF-κB/HIF-1α pathway

(2012) Guoqing Li et al.   MOLECULAR IMMUNOLOGY

Chondrogenic differentiation of growth factor-stimulated precursor cells in cartilage repair tissue is associated with increased HIF-1α activity

(2008) K. Gelse et al.   OSTEOARTHRITIS AND CARTILAGE