Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation

The therapeutic window of opportunity in rheumatoid arthritis: does it ever close?

(2015) Karim Raza et al.   ANNALS OF THE RHEUMATIC DISEASES

Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis

(2015) L Yeo et al.   ANNALS OF THE RHEUMATIC DISEASES

Mechanisms, impact and management of pain in rheumatoid arthritis

(2014) David A. Walsh et al.   Nature Reviews Rheumatology

The multifactorial role of neutrophils in rheumatoid arthritis

(2014) Helen L. Wright et al.   Nature Reviews Rheumatology

TRPA1 is essential for the vascular response to environmental cold exposure

(2014) Aisah A. Aubdool et al.   Nature Communications

Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse

(2013) Ine Vandewauw et al.   BMC NEUROSCIENCE

In pursuit of small molecule chemistry for calcium-permeable non-selective TRPC channels - mirage or pot of gold?

(2013) Robin S Bon et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood–brain barrier disruption and neurological deficits in stroke

(2013) Alessio Alfieri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of the TRPC5 ion channel protects the kidney filter

(2013) Thomas Schaldecker et al.   JOURNAL OF CLINICAL INVESTIGATION

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis

(2011) Sadaf Ashraf et al.   ARTHRITIS AND RHEUMATISM

Identification of ML204, a Novel Potent Antagonist That Selectively Modulates Native TRPC4/C5 Ion Channels

(2011) Melissa Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical Evaluation and Power Doppler Sonography in Rheumatoid Arthritis: Evidence for Ongoing Synovial Inflammation in Clinical Remission

(2011) Salih Ozgocmen et al.   SOUTHERN MEDICAL JOURNAL

Increased vascular penetration and nerve growth in the meniscus: a potential source of pain in osteoarthritis

(2010) S. Ashraf et al.   ANNALS OF THE RHEUMATIC DISEASES

2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) D. Aletaha et al.   ANNALS OF THE RHEUMATIC DISEASES

A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis

(2010) Elizabeth S. Fernandes et al.   ARTHRITIS AND RHEUMATISM

Essential Role for TRPC5 in Amygdala Function and Fear-Related Behavior

(2009) Antonio Riccio et al.   CELL

Tumour necrosis factor α mediates transient receptor potential vanilloid 1-dependent bilateral thermal hyperalgesia with distinct peripheral roles of interleukin-1β, protein kinase C and cyclooxygenase-2 signalling

(2009) Fiona A. Russell et al.   PAIN

Differential regulation of TRP channels in a rat model of neuropathic pain

(2009) Susanne Staaf et al.   PAIN

TRPC channel activation by extracellular thioredoxin

(2008) Shang-Zhong Xu et al.   NATURE

Contralateral hyperalgesia and allodynia following intradermal capsaicin injection in man

(2008) N. G. Shenker et al.   RHEUMATOLOGY