Composition of TWIST1 dimers regulates fibroblast activation and tissue fibrosis

Activating transcription factor 3 regulates canonical TGFβ signalling in systemic sclerosis

(2015) Tatjana Mallano et al.   ANNALS OF THE RHEUMATIC DISEASES

Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis

(2015) Michal Tomcik et al.   ANNALS OF THE RHEUMATIC DISEASES

Stimulators of soluble guanylate cyclase (sGC) inhibit experimental skin fibrosis of different aetiologies

(2015) Clara Dees et al.   ANNALS OF THE RHEUMATIC DISEASES

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

(2015) M Teresa Grande et al.   NATURE MEDICINE

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis

(2015) Katrin Palumbo-Zerr et al.   NATURE MEDICINE

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis

(2015) Sara Lovisa et al.   NATURE MEDICINE

From pathogenesis to therapy – Perspective on treatment strategies in fibrotic diseases

(2015) Andreas Ramming et al.   PHARMACOLOGICAL RESEARCH

S100A4 amplifies TGF-β-induced fibroblast activation in systemic sclerosis

(2014) Michal Tomcik et al.   ANNALS OF THE RHEUMATIC DISEASES

Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages

(2014) Christian Beyer et al.   ANNALS OF THE RHEUMATIC DISEASES

Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis

(2013) Michal Tomcik et al.   ANNALS OF THE RHEUMATIC DISEASES

Inactivation of evenness interrupted (EVI) reduces experimental fibrosis by combined inhibition of canonical and non-canonical Wnt signalling

(2013) Alfiya Distler et al.   ANNALS OF THE RHEUMATIC DISEASES

The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis

(2013) Clara Dees et al.   ANNALS OF THE RHEUMATIC DISEASES

2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative

(2013) Frank van den Hoogen et al.   ANNALS OF THE RHEUMATIC DISEASES

STAT3 mediates TGF-β1-induced TWIST1 expression and prostate cancer invasion

(2013) Kyung Hwa Cho et al.   CANCER LETTERS

Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis

(2012) Nicole Reich et al.   ANNALS OF THE RHEUMATIC DISEASES

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

(2012) Christian Beyer et al.   ANNALS OF THE RHEUMATIC DISEASES

JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis

(2012) Clara Dees et al.   ARTHRITIS AND RHEUMATISM

Clusterin Mediates TGF- -Induced Epithelial-Mesenchymal Transition and Metastasis via Twist1 in Prostate Cancer Cells

(2012) M. Shiota et al.   CANCER RESEARCH

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

The transcription factor JunD mediates transforming growth factor  -induced fibroblast activation and fibrosis in systemic sclerosis

(2011) K. Palumbo et al.   ANNALS OF THE RHEUMATIC DISEASES

Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms

(2011) Qian Qin et al.   CELL RESEARCH

HIF-1  Mediates Tumor Hypoxia to Confer a Perpetual Mesenchymal Phenotype for Malignant Progression

(2011) Y.-G. Yoo et al.   Science Signaling

Redundant or separate entities?--roles of Twist1 and Twist2 as molecular switches during gene transcription

(2010) H. L. Franco et al.   NUCLEIC ACIDS RESEARCH

Requirement of transforming growth factor β-activated kinase 1 for transforming growth factor β-induced α-smooth muscle actin expression and extracellular matrix contraction in fibroblasts

(2009) Xu Shi-Wen et al.   ARTHRITIS AND RHEUMATISM

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Twist: A Regulator of Epithelial-Mesenchymal Transition in Lung Fibrosis

(2009) Veronika Pozharskaya et al.   PLoS One

Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis

(2009) Christian Beyer et al.   ARTHRITIS RESEARCH & THERAPY

Twist1 homodimers enhance FGF responsiveness of the cranial sutures and promote suture closure

(2008) Jeannette Connerney et al.   DEVELOPMENTAL BIOLOGY